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johncearls

166 karma · joined November 28, 2018

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johncearls··on We're going to need a lot of solar panels
But this way is carbon neutral. Every CO2 molecule you pump out, started out as a CO2 molecule you took from the air. There is no reason to dislike fossil fuels, if they no longer come from fossils. It's the releasing of carbon from millions of years ago that's creating the excess.
johncearls··on News engagement plummets as Americans tune out
I think you mean bias, not conspiracy.
johncearls··on Found: The 'holy grail of catalysis'– turning methane into methanol
This is a pretty basic chemistry question, but I thought someone her might be able to give a simple explanation why it seems most of these amazing catalysts are always made from precious metals. Why is it that super expensive things like gold and silver and platinum are always the backbone of these catalysts?
johncearls··on SpaceX launches three Falcon 9 rockets in 36 hours
I want to know too. I would like to buy some shares, put them in a box and save them for my grandchildren. Seems the very definition of a long play to me.
johncearls··on SpaceX firings likely violate US labor law, experts say
Depends on the roles of the people who were fired.

> the NLRA is restricted to nonsupervisory employees, said Kate Bischoff,

And whether the statements themselves qualify.

According to WSJ , https://www.wsj.com/articles/spacex-fires-employees-involved....

johncearls··on US Army deploys its first floating solar array
I love Friday and just reread it last weekend. Often I think that Elon Musk believes he is a character in a Heinlein novel. Tesla is Shipstone, the cars are just a mechanism to build better batteries. SpaceX, that's just DD Harriman from the man who sold the moon/sail beyond the sunset. The Boring company is how you build Luna City ala The moon is a harsh mistress. Or maybe a space catapult. Or maybe, I'm just hoping for Heinleinian hero.
johncearls··on Gasoline Prices Reach $5 a Gallon Nationwide for the First Time
The democrats told us they wanted to get rid of carbon based fuels. This is what that looks like. There is no way to get to that without going through this.
johncearls··on Research may reveal why people can suddenly become frail in their 70s
Telomeres get a lot of press, but they are only one Hallmark of aging. Other possible related hallmarks I see in this include stem cell exhaustion, epigenetic disregulation, genomic instability and altered cell signaling. Note I have not read the paper and they may have identified other novel mechanisms. If this is a topic you find interesting, I recommend you Google hallmarks of aging. Morgan Levine also has a new book out that gives a nice overview of all the different ways the body messes up as it ages.
johncearls··on Oral administration of NMN is safe and efficiently increases blood NAD levels
I have to disagree with you on that. There are a great many mechanisms we evolved, most long before we were human, that appear to be anticancer mechanisms. Off the top of my head senescence, apoptosis, and telomeres. The fact we don't all die of cancer earlier is a result of this.
johncearls··on Cholesterol and mortality: Evidence of a U-shape Relationship
Your skin turns read and feels hot, like a sunburn. It's the number one side effect of high dose niacin. There are some prescription extended release prescription niacins to reduce that effect, but it still happens. It's very uncomfortable, which is a real problem for something you take daily.
johncearls··on Facebook, Google other tech firms must verify identities under proposed UK law
> The only reason it's not a total nightmare here is I'm sure the police are so underfunded that they couldn't take advantage of all this bullsh!t, even if they wanted to.

This actually makes it worse because this means it will selectively be used against "enemies" of the establishment. That and for select and well-publicized chilling effects.

johncearls··on Antiplatelet and anticoagulant therapy resolves long covid in 24 patients
It could also simply be time. To me this is obviously a small study that should be followed up (quickly) with a double blind, randomized trial. Until then, I'd be hesitant to put a bunch of ppl on anticoagulants.
johncearls··on Starlink Is Quietly Expanding, but Speeds Are Getting Worse
There was no mention of latency, which is the real game changer for Starlink vs other satellite providers. Seems like FUD.
johncearls··on Six dead after tornadoes destroy Amazon warehouse near St Louis
Fwiw, bathrooms are usually a good place to ride out a tornado. No windows and they are usually in a central location.
johncearls··on T-Wand: beating Lucene in less than 600 lines of code
Exactly this. I have a PHD in CS and am a world class expert in multi-omic data integration and analysis. I'm happy to throw my weight around in that area, but I'd never point to my PhD to pontificate on Neural nets or systems or queuing theory or 99 percent of CS. If getting a PhD doesn't teach you how much you don't know and how hard it is to develop real expertise in any area, I think you wasted your PhD. Note, my PhD isn't on the value of PhDs so take it as you will.
johncearls··on California legalized weed 5 years ago, but illicit market still thrives
I believe the enforcement is federal (ATF). I'd imagine until the fed legalizes it, the process will be messy. You would have to recreate the ATF in each state. ATF also has some pretty sweeping powers that may be tough to replicate (legally) on a state by state basis.
johncearls··on Too many new papers may mean novel ideas rarely rack up citations
While your parents have been flying in the same planes, they payed twice as much (inflation adjusted) and a lot less often.

I too wish I was vacationing in Luna City tovarich, but things have gotten better by quite a bit.

https://www.theatlantic.com/business/archive/2013/02/how-air...

johncearls··on Beyond Smart
I like this idea. Makes me think of nondeterministic v deterministic Turing Machines. It is easy to confirm that the magician is correct, but hard to see how they were able to get there.
johncearls··on A new biography of John von Neumann
My least favorite example of this is statistical "significance" which gives the impression of importance. I can't think of a word that has caused more trouble in science than that.
johncearls··on What Does Evergrande Meltdown Mean for China?
Thanks for pointing this out. FWIW, it appears China's number is actually 66.8%, vs the US's 108%. Your point still stands.

1 https://tradingeconomics.com/country-list/government-debt-to...

johncearls··on Biomarkers of dairy fat intake, cardiovascular disease, and all-cause mortality
I believe it is always cheaper to feed cows grass. The grain is more expensive, but fattens the cow up and produces better marbling, and most would say better taste. That is why it is done.
johncearls··on Turing Oversold?
I think the attraction to the Turing story is that it is a classical tragedy. If what happened to him happened to any gay man, it would be wrong. But since it happened to one of the greatest geniuses of the 20th century, who may have had other breakthroughs that could have pushed mankind forward, it is a tragedy. A tragedy for all mankind. Mankind suffered a huge loss due to its own moral failures.
johncearls··on YouTube deletes “lawsuit against vaccine passport” press conference video
The smart way to keep people passive and obedient is to strictly limit the spectrum of acceptable opinion, but allow very lively debate within that spectrum.... - Noam Chomsky, The Common Good
johncearls··on Does the Tuskegee experiment explain black vaccination rates?
In case you're interested, here's a recent preprint that breaks down the demographics of vaccine hesitancy: https://www.medrxiv.org/content/10.1101/2021.07.20.21260795v...
johncearls··on NYC to mandate proof of vaccination for many indoor settings
> Herd immunity is a form of indirect protection from infectious disease that can occur with some diseases when a sufficient percentage of a population has become immune to an infection, whether through vaccination or previous infections, thereby reducing the likelihood of infection for individuals who lack immunity.

Right from wikipedia.

johncearls··on NYC to mandate proof of vaccination for many indoor settings
> CDC Director Rochelle Walensky said recent studies had shown that those vaccinated individuals who do become infected with Covid have just as much viral load as the unvaccinated, making it possible for them to spread the virus to others.

This is why the CDC started recommending masks again.

https://www.nbcnews.com/politics/white-house/biden-administr...

johncearls··on NYC to mandate proof of vaccination for many indoor settings
Only the vaccinated will preferentially evolve variants that are resistant to the vaccine. The vaccines are leaky, as evidenced by the recent outbreak in the Northeast. A saner strategy with leaky vaccines is to vaccinate the small population that is vulnerable and let the rest of the population of develop a natural herd immunity. Otherwise you are creating a fitness advantage to resistant strains.
johncearls··on A blood marker predicts who gets ‘breakthrough’ Covid
Yeah. I did a lot of work with blood measures and every disease had some characteristic spike in n immune function. I worked in a lab with a ton of immunologists and we never knew what was going on. All we could say was activation of complement or strong TNF response or something else descriptive but not really helpful. Just too much dark matter in the immune system. My big hope is that the silver lining of COVID will be a much deeper understanding of the immune system. Certainly a ton of money is being poured into it. Fingers crossed, we could be entering a golden age for immuno-therapeutics.
johncearls··on What's Inside the EU Green Pass QR Code?
That's crazy. Governments always return the freedoms the take once emergencies are over. I'd find a citation but I am almost to the front of the line and need to remove my shoes.
johncearls··on My multi-decade quest for rural broadband
You've just invented the Republic. At least that's the way it is supposed to work. My opinion is that the House should be increased by a factor of 100. Hard to bribe that many people.
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