484 karma · joined April 22, 2022
To put it concretely, if the chance of a random gene mutation is 10^-4 to 10^-6 per gene per generation, and there are 37 trillion cells in a human body, each cell containing about 20k genes, (all numbers from quick google searches) then the odds of having NO genetic mutations occur in your body in one day would be (forgive my back of the envelope math, assuming a generation is 20 years): (1 - 10^-6)**(37 trillion * 20000 / 365 / 20). My calculator can't keep enough precision to make this nonzero. i.e., everyone has genetic mutations constantly which makes the title of the article completely uninformative.
I'm also not criticizing the study, I'm criticizing the article and your defense of it. If "you have to use the citations given to understand the broader context of the study" - then if the point of a pop sci article is to effectively communicate the salience of the paper to lay audience, then that broader context needs to be communicated too.
And I would argue that the article (not paper) does _not_ convey the qualitative conclusion of elevated rates of nonstandard mutations, because it doesn't reference the baseline at all! It doesn't even present it as a comparison, like "We found MORE mutations in astronauts than would be expected of non-astronauts" - it literally just phrases it as "We found mutations in astronauts", which, considering that non-astronauts are exposed to radiation and get cancer + epigenetic mutations as well, doesn't differentiate it from the normal expected observation.
Therefore - no more discussion of any hobbies at work or meetups!