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rdruxn

204 karma · joined January 7, 2017

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rdruxn··on Efficient method to capture carbon dioxide from the atmosphere
It’s also the metabolic changes in pH. CO2 is a proxy for ph as carbon dioxide acidifies the blood as it dissolves.
rdruxn··on Developing a cancer drug without Big Pharma: this hospital shows it can be done
To quote xkcd, "So does a handgun" https://xkcd.com/1217/
rdruxn··on Boeing Starliner launches first crewed mission
Starship (including the Super Heavy) weighs about 10x as much as the Starliner (including the Atlas V)
rdruxn··on Study shows dementia more common in older adults with vision issues
Do you have any evidence to support any of these claims
rdruxn··on Heavy marijuana use increases schizophrenia in men, study finds
I would counter that by pointing out that if your aim is to achieve a certain degree of bioavailability of TCH, you'd have to smoke a larger quantity of a lower-potency product, thus exposing yourself to more of the combustion by-products than necessary.
rdruxn··on Scientists found a 'leak' in photosynthesis that could be tapped into energy
Yes thank you. Midnight brain fart. It was Farxiga & Jardiance I was thinking of
rdruxn··on Scientists found a 'leak' in photosynthesis that could be tapped into energy
> 2. Glucose is transported in intestines via a glucose-sodium antiporter protein. Maybe we can find a drug that blocks this and you can eat as much sugar as you want! (Turns out you’ll have uncontrolled diarrhea if you do).

It's very cool! It's the SGLT protein. It's actually a sodium-glucose co-transporter and is why gatorade is so effective! It's the perfect mix of salt, sugar, and water to take advantage of that very protein (where salt goes, water follows).

And yes there is a drug that targets these - it's the SGLT inhibitors and they're very in vogue right now. Ozempic and Mounjaro are the two big ones in the news right now. They act on the SGLT I (found only in the kidney) so that you urinate more sugar. They don't act on the SGLT 2 (only found in the gut) but other medications in that class act on both.

But congratulations and alas! You nearly invented gatorade and a multi-billion dollar diabetes and weight-loss drug. Hardly bone-headed ideas.

rdruxn··on Billion-dollar airline routes
Deep vein thromboses are real. It is very much recommended particularly on long haul flights
rdruxn··on Are daily standups hurting your team?
>But teams behave in an infinite combination of size, members, companies, and time

Slightly off topic, but I realize this is a subject I'd be interested in reading more about. Would be interested in suggestions in the same vein as Creativity, Inc. by Edwin Catmull?

rdruxn··on Greek Delivery Giant Efood Faces Major Backlash over Worker’s Rights
I think they were trying to make a joke and meant “redundant” instead of “oxymoron”
rdruxn··on America has a drinking problem
Unfortunately, it isn’t outlier behavior
rdruxn··on How fit can you get from just walking?
> I’m pretty sure being thing helps you with your sugar.

Yes, adipose tissue contributes to insulin resistance and impaired glucose metabolism. Why? Not exactly sure. https://doi.org/10.1016/j.molmet.2019.12.014

rdruxn··on List of Proposed Etymologies of OK
Funny, I misread the comment the exact same way. He was not suggesting that “ok” is derived from “poppycock”
rdruxn··on Most statin problems caused by mysterious 'nocebo effect', study suggests
They didn’t say all side effects were attributable to nocebo effects.
rdruxn··on macOS Big Sur
Same, yet Apple's System Status still has marked the software update issue as resolved
rdruxn··on ‘Altered Carbon’ Canceled After Two Seasons at Netflix
Great, now they have time to make a Greg Egan tv show instead.
rdruxn··on Electrons May Well Be Conscious
https://en.wikipedia.org/wiki/Determinism
rdruxn··on OnlyFans, influencers, and the politics of selling nudes during a pandemic
How can you claim that porn is safe? You're completely sweeping porn addiction under the rug. Viewing porn itself is not inherently unhealthy, but to make a claim that it's safe is at minimum misleading.
rdruxn··on A synthetic control causal analysis of Musk's tweet on Tesla stock price
This is remarkable. I would love to see this in black mirror
rdruxn··on New York Governor announces 100% workforce reduction for non-essential services
Why are the subways still open? Seems like low hanging fruit to close those.
rdruxn··on iPhone 11 Pro and iPhone 11 Pro Max
The iPhone 8 is still included in their line up
rdruxn··on [dead]
Clickbait hyperbole and not news. Mods please remove this.
rdruxn··on Electric cars grab almost half of sales in Norway
http://www.laalmanac.com/transport/tr02.php

Looks a lot higher than that. Though 2016-2017 took a slow turn.

rdruxn··on Electric cars grab almost half of sales in Norway
>Doesn’t this negate a lot of the benefits of de-ICEing vehicles?

Sure some of the benefits, but the context is in the discussion of incentives and the attractiveness for the average buyer. 10km/day drivers have their needs sufficiently met with cheaper, shorter-range EVs.

rdruxn··on Suicide Rates Among Adolescents and Young Adults in the United States, 2000-2017
An argument / possible explanation that I've heard is that the increased risk for suicide can be attributed to the beneficial effect of reducing lethargy and fatigue, effectively removing one major barrier between suicidal ideation and carrying out the act.
rdruxn··on NASA Has Been Hacked
Wow what a horrible website - the entire article was nearly completely covered with popover ads
rdruxn··on Nasa Rover on Mars Detects Puff of Gas That Hints at Possibility of Life
One "dreadful"consequence could be quarantine lest we violate the prime directive
rdruxn··on Four Mars missions are launching next year
If it’s accelerating along the longitudinal axis, then the slant doesn’t matter. It’ll never experience more than 1g orthogonal to the axis.

The problem is getting out of the thickness of the lower atmosphere. That’s why rockets go up before they go sideways.

rdruxn··on Bees can link symbols to numbers, study finds
This really reminds me of the intelligent AI bees in Permutation City by Greg Egan
rdruxn··on A smartphone app that can hear ear infections in children
You're correct. They included a link to the actual paper: https://stm.sciencemag.org/content/11/492/eaav1102

According to the paper, they achieved 85% sensitivity and 82% specificity (N=98)

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