HNHacker News
TopNewBestAskShowJobs

gehwartzen

1,647 karma · joined July 25, 2016

Full Spectrum Human
submissionscomments
gehwartzen··on The protein Reelin keeps popping up in brains that resist aging and Alzheimer’s
My thinking as well. I’m fine with the FDA not giving drug approval to a substance as long as they don’t ban it. There are a few drugs I take regularly that are not FDA approved in the US (I.e Moclobemide as there are no approved reversible MAOIs in the US) but I’m still legally allowed to import them and usually it’s pretty cheap.
gehwartzen··on Philips Hue bulbs are randomly turning brightness to 100%
AFAIR the behavior of bulbs following a power failure can be defined in the app/hub. It doesn't necessarily have to come back at 100% brightness but that is the default behavior.
gehwartzen··on How I've Learned to Live with a Nonexistent Working Memory
Is there a good App that anyone can recommend to do this with speech to text? Something simple; just a searchable daily log that records bullets and timestamps with whatever I recorded. Ideally something that requires one click, tap, or shortcut to immediately allow transcribing to the correct entry page.
gehwartzen··on US Bans Kaspersky Software
First they came for my drug dealer…and I said nothing
gehwartzen··on Intel is trucking a 916k-pound 'Super Load' across Ohio to its new fab
Makes sense though if the route is already getting prepped for one load. It's a huge amount of work from logistical and coordinating effort (trains getting re-routed, hazmats cleared, roads shut down, etc) to get the route setup. May as well send any other extremely large shipments along while it's cleared.

Lots of companies have huge pieces of equipment sitting at factory X that they would rather have at factory Y for example.

gehwartzen··on Research as leisure activity
> look for people who have a university affiliation (that isn't just teaching) as a side gig.

Can you expand on this? Like people who have full time jobs in perhaps a different field but do research on the side using the facilities/resources of a university? If so how does one slide into a gig like that?

gehwartzen··on Horseshoe crab counting with New York’s citizen scientists
It seems it’s due to the synthetic not being fully recognized for equivalency in the US pharmacopia per this article:

https://www.npr.org/2023/09/23/1200620535/vaccines-are-still....

“ The blue blood of the horseshoe crab clots when it comes into contact with bacterial toxins, which helps technicians identify contaminated products. A synthetic alternative to the blood-derived testing ingredient, called limulus amoebocyte lysate, or LAL, was invented decades ago. Alternatives have since become mainstream; most of the east coast bleeding companies now also sell tests made with a synthetic, not just LAL, and the European Pharmacopoeia considered the synthetic ingredient equivalent to the crab-derived one in 2020. But since scientists at the U. S. Pharmacopeia had not yet done the same, drug companies that wanted to use them faced extra regulatory hurdles in the U.S.”

gehwartzen··on Centuries of milk marketing warped the way we think about dairy and nutrition
Milk and milk products with beneficial bacteria useful in digesting and tolerating said milk is what’s been around for millennia not the stuff we pick up at the grocery store.

Even though we’ve been doing it for a long time it still feels like an odd thing for the human animal to do. If one exists I can imagine a creator yelling “you’re not humming correctly!”

gehwartzen··on Google releases smart watch for kids
I grew up pretty unsupervised to run round town since I was around 7 or 8 growing up and definitely want the same for my son. He's 8 now and I got him an apple watch as I don't want him to have a large screen to distract him from the world but still be able to call/text his friends or get in touch w us in an emergency. I do not ever monitor his location (and told him as much) unless he reaches out to me and allows me to for help.

As with all things it's a tool and will depend on how the parents use it. If I break his trust by spying on him, well, thats on me and of course a rather difficult one to rebuild. I also told him if he ever wants to turn off location services we can do that but he's okey with it for now.

gehwartzen··on Arm says its next-gen mobile GPU will be its most 'performant and efficient'
We think you're going to be as excited as we are; Introducing our most powerful [product/chip] ever!
gehwartzen··on xAI announces series B funding round of $6B
This is probably the response Elon is looking for when he simply writes something vague that can elicit the imagination of any applicant’s specific worldview.
gehwartzen··on New findings point to an Earth-like environment on ancient Mars
I think there have been less than 100 drill holes by curiosity and perseverance the deepest being ~3” and none of those samples have returned to earth. Not sure how deep any potential fossil layers might be but that doesn’t sound like a lot.
gehwartzen··on Ethereum has blobs. Where do we go from here?
>As far as I can tell, the only cryptocurrency that actually delivers on its name (i.e. being used as a currency) is Monero. Sure, it's all drugs and stolen credit cards, but it does undeniably solve a real world problem for its users instead of just being used as a vehicle for speculative investment.

This is exactly my use case (the former not later) with Monero and it's been amazing. Only marginally more difficult than to shop on amazon and feels a million times less sketchy than trying to find something locally. The speculative nature of crypto is therefore more of an annoyance as it causes the price to fluctuate too much between paying, shipping, and fund-release.

gehwartzen··on Bees have an internal sense of time (2022)
Funny little cartoon I enjoyed wrt this subject:

https://falseknees.com/comics/405.html

gehwartzen··on Why don't grocery stores stock pawpaw fruit?
Yep. Here in Richmond they grow everywhere along the Janmes River Trail System.

Unfortunately, their popularity in the last few years has caused them to be over harvested by people selling them. Additionally, they taste the very best right after falling to the ground naturally but lots of folks keep trying to knock them or shake or climb the trees way to early in the season causing a lot of damage to the trees.

gehwartzen··on Amazon receives FDA warning letter for supplements with undeclared ingredients
I haven't hear about these problems at Walmart and would think the scale of stuff sold is comparable. I think the main problem, as others have mentioned, is that Amazon commingles products from various suppliers (so everything that comes in from a manufacturer or a true vetted wholesaler + 1000's of "flip stuff from china" garage operations get mixed up at Amazon warehouses before being sold).
gehwartzen··on Two pharmacists figured out that oral phenylephrine doesn't work
This is sadly so true for many many categories of consumer products; by the time sufficiently enough people discover the product is bullshit to turn general public opinion the original sales already made the "innovator" enough money to make the whole endeavor worthwhile.
gehwartzen··on Earliest Carpenters: 476k-year-old log structure discovered in Zambia
This was my initial thinking as well. Ive seen plenty of notched logs created by modern beavers when they give up on a project.

Perhaps not even an animal. I could imagine several scenarios where a perpendicular placed log could rub back and forth across another log creating a notch over time.

I guess it comes down to tool marks on the logs notched area but the whole thing is so weathered I can't imagine that evidence is crystal clear either. Its worth noting that the other tools, which the article mentions were found at the same site, are ~100k years younger.

gehwartzen··on Israeli Spyware Firm NSO Demands "Urgent" Meeting Amid Gaza War Lobbying Effort
Part of me wonders if the US support is at least partially secured by whatever information has on US Gov officials via NSO. As close as NSO and Israel are I would suspect whatever NSO digs up via contracts with other state actors is also known to Israel and im sure a lot of that is compromising US officials information.

I remember this story [1] story from a few months ago that goes into more detail about NSOs most recent entanglement with the US gov.

[1] https://www.engadget.com/fbi-investigates-use-of-nso-spyware...

gehwartzen··on Physical attractiveness and intergenerational social mobility
Can second this. Over the last few years I fixed some hormonal, dietary, and stress issues which resulted in much clearer skin, better hair, and more toned/muscular body; taking me from average to conventionally attractive based on commentary from friends/family.

There is a clear boost in first impressions generally being much more positive, my ideas being regarded more highly, and coworkers/leaders wanting to promote me. I don't think my intellect has changed much over that time.

I will say looking good also has a clear boost on self esteem and boldness which I'm sure at least partially contributes to the social changes.

gehwartzen··on Insta360's Ace Pro combines Leica engineering with computational photography
I have only experience with one of Insta360's product, the Link tracking webcam, but was left extremely impressed. The image quality was absolutely phenomenal. I imagine this action cam could only be even better working with Leica.
gehwartzen··on In the gut's 'second brain,' key agents of health emerge
Isn't it like saying the human body is a PC which has inputs (ports) and outputs (display, sounds) and the brain is like a CPU which has its own inputs and outputs? and you can always go further i.e the transistors have their own inputs and outputs
gehwartzen··on After Boeing declines to pay up, ransomware group leaks 45 GB of data
Out of curiosity how do you guys mentally interpret the data size when reading about a hack/leak story? 45GB? Do you think 10s of millions of text files? A few DVD rips? a server backup?

It seems so useless but is always portrayed as the "wow look at that number!" part of any leak/hack story

gehwartzen··on Justice Dept Says Collusion Suit Against Apartment Owners Should Move Forward
It's the same with jobs in most areas that aren't big cities or tech hubs; it's a huge pain in the ass to switch jobs if you aren't in a super high demand field. Often requiring a substantial uprooting and move.

Lots of uneven sectors where huge portions of individuals loose to "market forces".

gehwartzen··on Smart drugs reduce quality of effort, and slow decision-making
Having been on Adderall I agree with most here that it increases my executive function but doesn’t really make me smarter.

I have a long history of experimenting with both legal and illicit drugs and the only one I found to actually significantly increase my cognitive ability to solve complex problems is low dose Ketamine. Low dose lsd/shrooms as well but to a much lesser degree.

gehwartzen··on No bar exam required to practice law in Oregon starting next year
This is kind of a more general question but in terms of finding a good lawyer to do X what is the best filtering mechanism?

I’m one of those people that doesn’t have a “I’ll have my lawyer look at that” kind of relationship with anyone as I e never needed a lawyer. How would I best find a lawyer In my city if I have something come up and need one quickly? Is there a ratings system or reviews system? From the outside it’s like a big gray box with cost and word of mouth recommendations being the only sliders.

gehwartzen··on Psychedelics researcher approached his death with calm and curiosity
I have taken LSD and Shrooms countless times. I take MDMA multiple times a month as well. I guess the point though, for that example, was more along the lines of: take whatever substance floats your boat as much as you desire to remain in a happy state.

>"In my experience, these drugs don't mask your problems, they surface/amplify them."

MDMA will defiantly mask your problems. As will heroin, GBH, and a number of others. But yeah LSD/shrooms not so much.

gehwartzen··on Psychedelics researcher approached his death with calm and curiosity
Totally. Yeah the comparison was extreme and not meant to equate things.

>"It's true we shouldn't judge what works for someone without knowing them well, and even then, we can only offer suggestions."

Very well said. I have had great success with psychedelics and other mind-altering substances but doesn't mean the next person will. I have yet to reap a great benefit from therapy but perhaps I just haven't found the right therapist either. To each their own.

gehwartzen··on Psychedelics researcher approached his death with calm and curiosity
For me it depends on context; Pain exists for a purpose (i.e don't put wait on a broken leg otherwise you could extend healing time or make things worse) but if technology allows us to mitigate the potential problems (i.e fixing the bone and apply a cast will allow you to walk but not add strain) getting ride of pain in the meantime is probably a net good.

If you have chronic pain of some sort and you use substances to mask that pain the root problem hasn't been addressed and still exists, you just won't be aware of it. If loosing awareness (which at its simplest is what painkillers do) of the ongoing problem is okey with you by all means take a substance to mask it, just don't be surprised when the original problem grows worse latter.

Im okey with people masking or not masking. It should be a personal choice free of judgement.

There are two guys and both are extremely depressed. One guy decides to seek out a therapist and has a meeting set for two weeks from now, the other guy decides to take MDMA/LSD/shrooms (or whatever) every day. He feels amazing and is living his best life every day. The first guy is super depressed day to day but maybe the therapy will help...

The next week they are on a plane together that crashes. Who made the better decision?

Alternatively they don't die and instead live decades more. The first guy got to the root of his issues and lived a very happy life while the second eventually burned out and fell into even deeper depression for his remaining years. Who made the better decision?

It is not fair for us to judge others on how they would like to treat their own bodies and minds. We don't know the totality of their path through life.

gehwartzen··on Psychedelics researcher approached his death with calm and curiosity
If one could do you think that would be a problem?
← PreviousPage 4 of 16Next →