If you have chronic pain of some sort and you use substances to mask that pain the root problem hasn't been addressed and still exists, you just won't be aware of it. If loosing awareness (which at its simplest is what painkillers do) of the ongoing problem is okey with you by all means take a substance to mask it, just don't be surprised when the original problem grows worse latter.
Im okey with people masking or not masking. It should be a personal choice free of judgement.
There are two guys and both are extremely depressed. One guy decides to seek out a therapist and has a meeting set for two weeks from now, the other guy decides to take MDMA/LSD/shrooms (or whatever) every day. He feels amazing and is living his best life every day. The first guy is super depressed day to day but maybe the therapy will help...
The next week they are on a plane together that crashes. Who made the better decision?
Alternatively they don't die and instead live decades more. The first guy got to the root of his issues and lived a very happy life while the second eventually burned out and fell into even deeper depression for his remaining years. Who made the better decision?
It is not fair for us to judge others on how they would like to treat their own bodies and minds. We don't know the totality of their path through life.