If one could do you think that would be a problem?
Daily use of lots of substances, e.g. alcohol, isn't necessarily a bad thing in itself (though it really can be), but if it's to escape a problem then there's a serious risk there. As the above suggested, the problem also remains unresolved.
So yeah, I don't think a person self-medicating on a daily basis is always problematic, but it's never worked out well for me, and it's not something I'd advise.
My original point was really that getting out of one's head once in a while can give a fresh perspective on a problem.
Caffeine? Probably the most used and least worst, could still cause sleep disruptions.
Weed? Could be a problem. It's very easy to get mentally addicted to it and turn you into a bowl of mush, but if you're using it in medical doses I imagine it's less so.
Microdosing LSD? Depends from person to person. I think using it too often isn't good for the heart.
Alcohol? Absolutely a problem, even if the worst side effects take years to manifest.
These rhetorical attacks on Alcohol in an attempt to normalize the use of other chemicals without a similar biological history is asinine.
I'd be more concerned with psychological damage.
People who drink alcohol typically don't go around telling people they communed with entities from another dimension and they realized that all of existence is one harmonious unity.
Or whatever.