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broguinn

117 karma · joined September 4, 2013

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broguinn··on Using AI to negotiate a $195k hospital bill down to $33k
Doesn't the AMA serve the medical industry? They don't have to make profits themselves. If a byzantine coding process raises medical treatment costs, they'll do it. Just like how they intentionally cap med school admissions to keep doctors in demand and inflate their salaries.
broguinn··on Roc Camera
+1. To all of the marketing site developers out there: never mess with scrolling defaults.
broguinn··on Show HN: Autism Simulator
I don't know if this is useful for you, but getting my MTHFR and COMT genes sequenced has been incredibly helpful for managing my own mental health. Since getting these results, I've been able to understand my own neurology better.

I'm sorry to hear about your issues with sleep - and can relate to them. In particular, my slow COMT means that my baseline cortisol is higher than most. Taking phosphatidyl serine before bed helps me a lot, and lets me sleep through the night.

Best of luck.

broguinn··on Want to piss off your IT department? Are the links not malicious looking enough?
Who among us can compare with that colon?
broguinn··on Try the Mosquito Bucket of Death
I added 6 mosquitofish to my 110 gallon container pond two months ago. There are now nearly 100 in there, and the mosquito count in my back yard has definitely diminished.

Cool mosquitofish facts:

- An adult female can eat between 300-400 mosquito larvae in a single day.

- They're highly tolerant of low-oxygen and high-temperature water. They're hardy fish.

- They're native to North America, so pose little risk to getting into the water system, as they're already there.

- They're so effective at reducing mosquito populations, some local governments give them out for free.

src: https://en.wikipedia.org/wiki/Mosquitofish

broguinn··on A proposal to restrict sites from accessing a users’ local network
Ahh, thanks for clarifying! It's the origin being compared, not the context - of course.
broguinn··on A proposal to restrict sites from accessing a users’ local network
This Web Security lecture by Feross Aboukhadijeh has a great example of Zoom's zero-day from 2019 that allowed anyone to force you to join a zoom meeting (and even cause arbitrary code execution), using a local server:

https://www.youtube.com/watch?v=wLgcb4jZwGM&list=PL1y1iaEtjS...

It's not clear to me from Google's proposal if it also restricts access to localhost, or just your local network - it'd be great if it were both, as we clearly can't rely on third parties to lock down their local servers sufficiently!

edit: localhost won't be restricted:

"Note that local -> local is not a local network request, as well as loopback -> anything. (See "cross-origin requests" below for a discussion on potentially expanding this definition in the future.)"

broguinn··on New Study: Waymo is reducing serious crashes and making streets safer
The above comment is getting downvoted, and I suspect it's due to a misunderstanding of their intent. Yes, high speeds can make collisions (especially, as another commenter points out, to pedestrians and cyclists) more dangerous. However, just as human drivers subconsciously speed up when part of a group of cars, they are not often conscious of the environmental queues informing the speed at which they drive. Given the poster's allusion to 'stroads', I suspect that they're in favor of traffic engineering patterns that encourage speed reduction based on safe context queues without solely relying on an unenforced and often unobeyed traffic speed.

Consider this video on Dutch traffic calming: https://www.youtube.com/watch?v=bAxRYrpbnuA.

Lane narrowing, raised walkways, curves in the road (chicanes), etc. are all environmental queues that enforce safe traffic speed based on context, without relying on conscious human compliance.

broguinn··on Medieval
I ordered the KO-II for a friend, after reading about it on Hacker News. I love Teenage Engineering's playfulness and creativity, but was disappointed when the KO-II had quality issues with its input nob, making it unusable.

They were quick to issue a refund, but I would have loved to see them fix the underlying issue and offer us another unit. I'd have the same concerns about this model, since it looks like it uses the same base hardware.

broguinn··on Caffeine suppresses cerebral grey matter responses to chronic sleep restriction
I haven't seen this mentioned in the comments yet, so I'll mention it here. For the last year, I've seen health pundits (Huberman, etc.) recommend delaying caffeine intake for two hours after waking, for the purpose of allowing adenosine to clear from the brain first.

Ever since I've adopted this strategy, I find myself avoiding a mid-morning crash, and generally feeling more alert in the mornings. I wonder if the deleterious impact on grey matter could be mitigated in part by delaying consumption until fully awake.

broguinn··on People hate the idea of car-free cities until they live in one
This hasn't been my experience.
broguinn··on Flowers grown floating on polluted waterways can help clean up nutrient runoff
Very interesting - thank you for sharing his work. From my very cursory glance at Todd Ecological's homepage, their projects look scaled to individual residential and commercial wastewater filtration applications. I was hoping to see examples of filtration systems that would scale to entire regional watersheds, such as urban lakes.

In fact, this is something the [Beemats website](www.beemats.com] lacked as well: basic calculations to right-size their solution for a given body of water, flow rate, and nitrogen/phosphorous PPM. With that, you would know that so many square meters of plantings of X plant species would remove enough water pollution.

broguinn··on Flowers grown floating on polluted waterways can help clean up nutrient runoff
Here in Austin, Texas, we're lucky to have Ladybird (Town) Lake downtown. For most of the year, algae blooms are so severe that it's not safe for people or dogs to swim in the lake. It drives me crazy that people consider this anything other than anthropogenic.

I would love to see any effort to filter out urban water pollution. And I commend any change in the narrative that undesirable populations of blue/green algae, zebra mussels, etc. are inexplicable inconveniences, instead of what they really are: opportunistic growths driven by human water pollution and a warming climate.

broguinn··on Who makes the most reliable new cars?
Someone flashed their lights at me this very morning at around 5:00 am. At first I thought it was because my lights were off, then realized they thought my brights were on. They weren't, it's just that my new car has LEDs that are - apparently - quite bright.
broguinn··on Gut epithelial barrier damage caused by dishwasher detergents and rinse aids
I've looked at the dishwasher detergents at a few of my local grocery stores, and all of them contain either ethoxylates or "fatty alcohol alkoxylates", which some brief googling tells me are a class of chemicals that include ethoxylates. I've been unable (even at specialty health food stores) to locate a dishwasher detergent that lacks this class of chemical. If you find a brand that doesn't contain it, please let me know.

I also looked at home-made detergent recipes, as we've had good luck making our laundry detergent, but the blog I looked at showed severe streaking and residue on their example dishwasher load. I can't say that appeals to me, either.

broguinn··on Apple unveils the new MacBook Pro featuring the M3 family of chips
Wow, way to drop the Baldur's Gate 3 spoilers, Apple!
broguinn··on Common infections can spark psychiatric illnesses in children
There's some evidence that NAC can improve long COVID-like symptoms:

https://medicine.yale.edu/news-article/potential-new-treatme...

Other than antibiotics to clear a lingering infection, are there interventions that we might take in the aftermath of bacterial or viral infection to remediate long-term effects?

broguinn··on DJI Mini 4 Pro
I had the same thought seeing the hero videos on this page displaying beautiful mountain scapes and vistas - I wouldn't want to be the person disturbing this space with an intrusive drone.
broguinn··on The Tyranny of the Marginal User
Are you sure this data is accurate? By the site you reference, r/nottheonion has ~30 comments a day: https://subredditstats.com/r/nottheonion

But if I actually visit the subreddit, I see many posts from within the last 24 hours with 300+ comments each. Is it possible subredditstats.com had some kind of regression in its counting around that time? It could be related to the API changes.

broguinn··on The Tyranny of the Marginal User
Your point is a good one - what you're describing I've heard referred to as "the novelty effect". In fact, a lot in this article reminds me of another essay critical of the short-sightedness of many A/B tests:

https://www.zumsteg.net/2022/07/05/unchecked-ab-testing-dest...

broguinn··on Growing scientific interest in vagus nerve stimulation
I read the same book, and while it did help me in several respects (nasal breathing, mandibular and maxillar expansion via an orthodontic device, mouth taping), I only used its box breathing techniques under acute stress. It wasn't until I read a chapter in Peter Attia's Outlive about breathing techniques that I started changing my breathing in a way that, for me, feels like it's actively stimulating the vagus nerve. Here's how it works.

You want to breathe to expand your entire diaphragm, breathing into your upper and lower chest. One way to do this is to breathe through your nose slowly enough that you can't hear the sound of your own breathing.

To get a hang of it, lay on your back on a flat surface, place a hand on your stomach and a hand on your chest, and breathe in slowly. You should feel your stomach and chest rise evenly, neither too much in the stomach, nor too much in the chest.

Once you understand this feeling, you can practice it throughout your day. You feel your whole diaphragm expand, feeling the tension through your chest, stomach, and even expanding into your lower back. Anyways, that's how it's described in the book. I can say that since starting this breathing technique, I've felt a lot calmer. Best of luck, check the book out if you'd like a far more detailed and accurate explanation than mine.

broguinn··on Nanoplastic Ingestion Causes Neurological Deficits
I also learned in a Not Just Bikes video that the US tire lobby prevents regulation on quieter car tires. I bet there are ways to make tires that shed fewer microplastics - it's just that we don't do it.
broguinn··on Health officials delayed report linking fluoride to brain harm
Israel has completely stopped fluoridation.
broguinn··on New work helps to explain how chronic stress can inflame the gut
This, so much this. My family often jokes about how I'm the health and fitness "freak", because I care about my wellbeing and stress levels. However, this is very normal in my social circle - and I would argue - in my class and generation. A few examples come to mind:

- The rise of social/fitness loci. Young people socialize through sports, cycling groups, climbing gyms. - The advent of data-driven fitness. So many people have wearables, sleep trackers, follow the science behind health (Huberman podcast, Rhonda Patrick, etc.). - More people are opting for healthier living, generally (regular bedtimes, stopping or greatly limiting drinking, removing stigma from mental health diagnoses).

It feels like this generation is the first to really prioritize physical wellbeing as a primary driver of overall quality of life. I sincerely hope this trend sticks, and we look back 20 years from now and are surprised that so many people for so long neglected the fundamentals of health.

broguinn··on Layoffs push down scores on Glassdoor – how companies respond
I'm sorry they didn't hire you because of your disability. IANAL, but I suspect that your disability is a protected status in the United States. I'm not saying that you should've pursued legal action, but that what they did is both immoral and illegal.
broguinn··on The Staff Engineer's Path – Book Review
Read this; helped me get to staff. Some takeaways:

- If your management chain isn't supporting you into a staff promo, it's because they don't value the work you're currently doing.

- A staff engineer isn't a highly-productive senior engineer. Stop optimizing for the things that got you promoted to senior.

broguinn··on Widely used chemical strongly linked to Parkinson’s disease
I thought of this exactly. Is the Desulfovibrio bacterium's presence correlative with TCE exposure?
broguinn··on Widely used chemical strongly linked to Parkinson’s disease
Filter your drinking water. From the Minnesota Dept. of Health:

"Activated carbon filtration can remove TCE from drinking water effectively."[1]

[1] https://www.health.state.mn.us/communities/environment/hazar...

broguinn··on Carbon-negative concrete
> Biochar is made today by heating waste materials like wood chips, rice husks, or *water-treatment sludge* at high temperature in a low-oxygen environment.

Holy shit.

broguinn··on A bacterial culprit for rheumatoid arthritis?
The gut-brain axis is so important. It's only natural that commenters here would want to know when a treatment for RA is available based on these findings. Nothing's for certain, but it wouldn't hurt to improve your gut biome.

- Take a probiotic and prebiotic daily. Swanson sells a bunch of cheap and high-quality ones. - Some people have had luck improving their gut health with supplementing collagen peptides. YMMV.

Obviously, the gold standard is a double-blind study that proves the effectiveness at eliminating rheumatoid arthritis through intervention. Both of the above suggestions are well-tolerated in the general populace.

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