I recall Terrence McKenna (everyone's favorite historical psychonaut) saying "It's hard to do psychedelics". I agree with him. These things are dangerous when the set and setting is wrong, or if they're done at an off-kilter phase of your life, or that you simply over-indulge in them.
I appreciate the mini renaissance period they're having these days, but these things need plenty of research before trying them. They're not something you do for a giddy high, they're tools. One thing people need to do is integrate the various lessons they've gained from tripping into their daily lives.
All too often, trips are like dreams, they fade and we suffer amnesia after trying them. It's crucial to take notes and integrate the ideas you've gained, otherwise you've wasted the trip(s) IMHO.