6,025 karma · joined April 8, 2017
More than 95% of all proteins located in the mitochondrial compartments are encoded by the nuclear DNA, synthesized in cytoplasmic ribosomes and imported into mitochondria. These include factors that regulate mitochondrial DNA (mtDNA) gene expression such as mtDNA and RNA polymerases, mitochondrial transcription factors, RNA processing and modifying enzymes, transcription termination factors, mitochondrial ribosomal proteins, aminoacyl-tRNA synthetases, and translation factors (1, 2).
It's clear that a mitrochondrial element can't live for long without the presence of the host cells, so, like a virus, it doesn't meet all the requirements to be considered fully living.
One of my favorite flag signals is, “Nothing can be done until high tide.”
Maximum hype, complete with artist's concepts. It's hard to believe that this is the website of an astrophysics project, but it is.
Why not just use something closer to the metal: Common Lisp, Scheme, Clojure, Racket? Especially, use a compiled language, instead of an interpreter.
With Waterfall, there is an upfront spec, but implementing the whole thing without consultation with the customer can be a bad experience.
With Agile, maybe there's a lot of internal correction. But the key thing is to involve the customer in integration testing. Unless both sides are very experienced, surprises due to miscommunication are the rule.
I find it best to have a separate journal for each downloaded account. I just include them into a master journal (along with a manual entry journal) and generate reports from that.
I also use git so I can roll back the latest import, if something goes wrong - but that hasn’t happened yet.
Their structure seems to have been like a private corporation, with special rules and efforts to maintain their ideology and culture. They had the ability to expand outside the current leading families when necessary, though.
When they hit the recent hard patch, they pivoted, but didn’t scale back enough to survive until the next great leader showed up. They fell into the hands of modern corporations, and we all know how that turns out.