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oldgradstudent

3,614 karma · joined December 7, 2017

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oldgradstudent··on Thirty Years Later, a Speed Boost for Quantum Factoring
Great.

You now only need O(n^1.5)* magic bits instead of O(n^2) magic bits.

* Or O(n) according to other comments

oldgradstudent··on Causal inference as a blind spot of data scientists
You should open a epidemiological journal these days. Half the papers are either as bad as "umbrellas causes puddles" or obviously confounded with socio-economic status.
oldgradstudent··on Causal inference as a blind spot of data scientists
It's pretty simple. You cannot infer casualty from observational data. No matter how sophisticated your statistical tools are.

You need to perform a properly controlled experiments to infer casualty. And even then it's hard.

Inferring casualty from observational data is cargo cult science.

oldgradstudent··on Living in privately rented homes linked to faster biological ageing, study finds
It's not only the journalists that are in fault here.

There's a huge academic industrial complex generating this type of crap.

oldgradstudent··on Living in privately rented homes linked to faster biological ageing, study finds
Usually the variables correlated with socio-economic status.

The vast majority of epidemiological papers are basically correlations with socio economic status.

oldgradstudent··on 2023 Nobel Prize in economics awarded to Claudia Goldin
Turing wasn't nearly as well known as he is now. The cryptoanalysis of the Enigma remained classified until the early 1970s, long after the Turing award was established (the first award was given in 1966).
oldgradstudent··on 2023 Nobel Prize in economics awarded to Claudia Goldin
There are plenty of awards granted for great work in computer science, electrical engineering, or any number of other fields.

It doesn't make them Nobel prizes.

At least the ACM never attempted to hang on the coattails of the the Nobel Prize by naming the Turing award for Alfred Nobel.

oldgradstudent··on 2023 Nobel Prize in economics awarded to Claudia Goldin
If the ACM, instead of founding the Turing award, had attempted to pay to get a Nobel memorial prize in Computer Science, we would have easily recognized it for what it was - a pathetic play for respectability.
oldgradstudent··on Nature flags doubts over Google AI study, pulls commentary
Related discussions:

https://news.ycombinator.com/item?id=36501194

https://news.ycombinator.com/item?id=35441759

oldgradstudent··on Nobel Prize in Medicine awarded to Katalin Karikó and Drew Weissman
Again, the debate started over the claim that

>>>> Vaccination was never about "not getting it".

Of course it was about whether the vaccine prevents you from "getting it" (it being Covid). The original claim was that it was 95% effective in preventing you getting it.

> We have loads of evidence of it lessening symptoms; for a non-zero amount of people, that'll mean going from symptomatic to asymptomatic, i.e. SARS-CoV-2 infection but not COVID-19.

We have loads of crappy evidence showing that (see below). Crappy means highly confounded observational data.

> Vaccines have never been expected to be perfect in this regard; some polio vaccines can give people polio, for example.

No one expects them to be perfect, but the original claims were they were supposed to be 95% effective in preventing Covid. Real world efficacy is no where near that. If there's any efficacy at all it is in the low teens.

[BTW, there's a huge debate about the oral Polio vaccine. The US stopped vaccinating with it two decades ago because of that risk]

> (The idea that "turns out it only prevents hospitalization and/or death, not mild symptoms" is a bad result is also lunacy from the start.)

It would be luncay if anyone actually claimed that.

The problem is that claiming that it prevents hospitalizations or deaths requires evidence. Reliable evidence.

A recent NEJM correspondence demonstrates quite vividly how terrible much of the evidence for that claim was:

https://www.nejm.org/doi/full/10.1056/NEJMc2306683

(the original author's response is especially hillarious)

oldgradstudent··on Nobel Prize in Medicine awarded to Katalin Karikó and Drew Weissman
> You called that very statement a "bizarre claim" upthread.

The discussion was about Covid. Covid is the disease (infection+symptoms). The vaccine was supposed to prevent you from "getting it".

oldgradstudent··on Nobel Prize in Medicine awarded to Katalin Karikó and Drew Weissman
The vaccine was never approved for reduction of symptoms because there was no good evidence to make this claim. And there's no good evidence to make it now.

It was approved for the prevention of Covid (the 'D' stands for disease). It was supposed to prevent you from getting Covid, regardless of severity, and it didn't.

And if we're citing anecdotal evidence. I know of no one who got anything more than flu symptoms, and for most it was mild, regardless of vaccination.

That includes obese diabetic 80s year olds. I know of no one personally who went to the ER except for a vaccinated friend who panicked.

oldgradstudent··on Nobel Prize in Medicine awarded to Katalin Karikó and Drew Weissman
The trials were never powered to even test for infetion or transmission. It is quite clear now the vaccine prevented neither.

It was supposed to prevent the disease - basically postive test + symptoms. It didn't.

oldgradstudent··on Nobel Prize in Medicine awarded to Katalin Karikó and Drew Weissman
>Vaccination was never about "not getting it".

What do you base this bizarre claim on?

From the package insert for the Pfizer vaccine:

> COMIRNATY is a vaccine indicated for active immunization to prevent coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in individuals 12 years of age and older. (1)

A single indication, "not getting it". This is what the clinical trials tested and this is what the FDA approved.

oldgradstudent··on The presumption that computers are working correctly
No.

Hardware people are fully aware of their shortcomings, but they also are fully aware that software is even worse.

Far far worse.

oldgradstudent··on VLSI Physical Design
Similarly out of date.

A good starting point for more modern techniques would be something like this:

https://people.eecs.berkeley.edu/~alanmi/publications/2006/t...

oldgradstudent··on VLSI Physical Design
It hasn't been updated.

The book is considerably out of date, but a lot of the concepts and definitions are still relevant.

oldgradstudent··on In depression treatment trials, placebo effect is growing stronger
Every study is done on a different population and with a slightly different protocol. The only thing a placebo gives it is being able to compare the treatment to the natural course of the disease.

You compare between different placebo groups in the same study, but comparing between different placebo groups in different studies is cargo cult science.

oldgradstudent··on Turkish man arrested over posting photo to Reddit with alcohol in mosque
So you're telling me that if I bring, for example, a pig into a synagogue I won't face any legal repercussions?
oldgradstudent··on In Germany, 27 are in 'preventive detention' b/c they might do climate protests
> One of their things to do is to glue themselves down in places to hinder others, think at events, on streets, tracks, airfields, etc.

One would think that people gluing themselves to things is a self limiting problem.

oldgradstudent··on Intel announces Arm investment, talks up RISC-V
It's not just the last decade

Does anyone remember ViiV, or explain what exactly it was?

oldgradstudent··on The Gimmicks of Food Labeling
Just returned from Athens, Greece. There was an ice cream place called "Sugar Killer" that claimed to be "Sweet N Sugarless"

I was curious and asked what sweetener they were using, expecting something like Erythritol.

Turns out "sugarless" means Agave Syrup.

Edit:

https://sugarkiller.gr/

Not envying the naive Diabetic that falls for this.

oldgradstudent··on Antioxidants found to spur cancer growth and metastasis in mice
That's why observational studies consistently show vitamin deficiency correlates with various types ill health, but controlled experiments consistently show that supplementation fails to improve it.
oldgradstudent··on The real cost of a preventive health scan goes well beyond the price tag
Some people believe in data like other people believe in God.

Data is meaningless without context and without knowing how reliable it is.

PSA tests, for example, provide data that sent a lot of people to an early grave, or to years of unnecessary treatment and anxiety.

oldgradstudent··on The real cost of a preventive health scan goes well beyond the price tag
Has it ever been shown that full body scan reduces mortality or morbidity?

The simple answer is No. It may, or it may not. Probably not.

It's not even clear that mammography or colonoscopy reduce mortality or morbidity.

oldgradstudent··on Helicopter Footage Reveals State Trooper Surveillance Capabilities
Yes, but otherwise, there is no permission required for a peaceful assembly.
oldgradstudent··on Helicopter Footage Reveals State Trooper Surveillance Capabilities
> Weird article, a protest can be peaceful, but dont you need a permission?

The first amendment is quite clear about it

> Congress shall make no law ... abridging ... the right of the people peaceably to assemble, and to petition the Government for a redress of grievances

oldgradstudent··on The complete sequence of a human Y chromosome
They now have the raw data for the CAD files used for manufacturing the keyboard.

We understand some CNC instructions, but there's no good understanding of the control mechanisms or sequencing.

One day we'll identify the keys, but we are very far from the driver, and more importantly, from identifying what each key does.

Oh, we did discover that changing specific bits in the raw data causes the keyboard to fail in interesting ways.

oldgradstudent··on Microsoft retracts AI-written article advising tourists to visit a food bank
Not sure intelligence is involved in writing articles on The Verge, artificial or otherwise.
oldgradstudent··on A look into the finances of SpaceX
How are Starlink launches accounted for?

Are they considered revenue? Capex? Expenses?

I guess it depends on the exact corporate structure.

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