ohbleek

The obstacles for lab-grown meat are conceptually similar to the “impossible” obstacles people were claiming would prevent ever bringing the electric car to market successfully. The same kind of circumstances are being ignored and the time it took to achieve the current state of industry is being ignored. Just like the electric car, there is an enormous group of people that want to see lab-grown meat fail.

Hi, I’m terrible at navigating HN and I can’t remember my login in order to use anything besides my mobile to post here BUT I saw you replied to a comment of mine 2 months ago regarding CFTR modulators for treating cystic fibrosis. You concluded your response by saying the drugs are prohibitively expensive and I wanted to let you know that if you have any of the qualifying mutations (there are A LOT) you wouldn’t need to pay for the medications as there are funds and grants that will cover the costs of therapy for CF patients. If you want some more information I can try to get you the resources you need. I’ve seen these medications change lives and I hope they will be available for all mutations some day, perhaps yours is already.

Unfortunately “let everyone be themselves” is very far from modern libertarianism in practice. “Libertarian” has become a label for people who want to argue in bad faith for conservative positions while claiming to not be conservative or republican. Ask almost anybody that claims to be libertarian if they support the eradication of state/national borders, freedom to carry out an abortion at any stage of pregnancy or any other idea that runs counter to current republican talking points and you’ll quickly see through the facade of their libertarian label.

This comment reads like an attempt at poorly executed propaganda. The comparisons drawn are not only inaccurate but borderline nonsense.

Title is misleading. Change it.

CFTR modulators have completely transformed CF treatment for +90% of patients. Gene therapy is a possibility, however, with there being +1000 possible mutations that can lead to CF, it’s not the clear cut candidate that some of the other rare genetic disorders are right now. The cynic in me also thinks that with CFTR modulators costing ~350k/year, drug companies may not feel incentivized to run the risky gene therapy trials and patients may not want to participate given the dramatic improvement in their lives with current therapy options.

Saying homosexuality shouldn’t be legal isn’t an opinion, it’s bigotry. Viewpoints that infringe on a persons rights are not opinions, it’s discrimination. I agree people should be able to speak freely but I also believe in standards. To take another example, if somebody has the “opinion” that women shouldn’t be able to refuse their husbands sexual advances, is this discussion that is acceptable or is it bigotry? Should people be able to openly discuss their “opinion” that adults should be able to have sex with minors? What if their opinion is that they should be allowed to kill homosexuals? There is a line. Idealism only goes so far.

I use the lightning network almost daily and I’ve never done that. I just use a wallet that is lightning capable and that’s it.

I very much appreciate the way you’ve discussed these topics in this thread. You definitely have a tendency to give people the benefit of the doubt and I don’t think that quality is inherently faulty. I do think we have to recognize that some actions may require a certain level of sociopathic behavior and that sociopathy is very real.

Longreads.com is the site for you.

+1 for firefox focus, it is the browsing app I use for iOS unless I want to come back to something later then I'll open it in safari, from focus

Thank you for sharing this story! I have regretted not going to that tour for years now. I just didn’t have the money but I wish i had found it because I would have been in those cheap seats screaming for Clifford too!

This conversation begins when the number of residencies increases. And that will not change until congress approves more funding for residencies. Until then, there will be no change.

Zotero is a game changer. Citations have become the easiest part of writing and the tagging feature is incredibly useful when doing a systematic review.

I never liked the idea until I started using a browser based pomodoro timer and I enabled the desktop notifications, it's been a useful feature. Now, I'm wondering if there are other benefits I've been missing out on since I have always disabled desktop notifications by default.

I remembered your comment today because we had a doctor call our pharmacy to order +1000 hydroxichloroquine tablets for everybody in his assisted living facility, requiring 12 tablets per patient for prophylactic use. Our Pharmacist in charge referred him to literature and informed him they would need an Rx for each patient even if we had that kind of supply, but overall this was not an appropriate practice without a full list of all medications that patients are currently taking. Anyway I thought you'd find this interesting.

AirBnB failed. I don't even check it out anymore when I travel because a hotel typically costs about the same due to the fees charged by the hosts. I would choose a hotel over AirBnB until the price difference is 15-20% lower in favor of AirBnB because there are too many unknowns with AirBnB and the novelty has worn off entirely. Plus since so many listings are owned by some company or person renting out multiple locations, whats the difference any more?

Are you aware of any other forums with high quality discussion? The quality of discussion here can be found occasionally in a few subreddits but they are even more niche and users have less decorum overall.

This lines up with my own experience and with advice I've read about "being successful." Essentially that, until you're at the top of the food chain, credit should always be deflected upward. Personally I bump up against the idea that it is good to do that in all situations, however, I have yet to find myself in one.

I have NOT found that, when taken at a therapeutic dosage, people with ADD/ADHD thinktheir medications are fun other than the "fun" feeling of satisfaction you get when you complete a task.

I have found that people who do not have ADD/ADHD find those same medications to be fun, however, even at a therapeutic dose.

Otherwise your comments on the effects are spot on. Personally I had to make a choice in my mid-twenties, the meds or a happy-go-lucky life where I feel unfulfilled but I have a fun time.

I used to just sit all day, thinking about what I needed to do, yelling at myself in my head to do it, but never doing anything. Just constant maladaptive daydreaming. I have inattentive type ADD. I didn't develop mental executive functions until I was 28. I started recognizing there was a "manager" in my brain that wasn't there before. I sobbed when I found out most of my peers developed that 10 years earlier.

From what I've seen, people with ADD/ADHD go through a cycle of recognizing then denying that they have a disability. I have done this personally 4-5 times in my life. I will accept I have a disability and deal with it, then eventually decide that it was my environment that was causing the symptoms, only to later come to a point where I once again have to accept I have a disability that cannot be managed entirely with CBT, task lists, meditation, mindfulness, etc... I'm happy for those that feel they can do it without medication, but I also have to wonder if I'm just meeting those people at a point in time before they have to get back on medication again...

I can't take Ritalin. I get mood swings and suicidal ideation. Adderall, however, changed my life. Have you tried other medications?

I also find that a vegetarian diet, low in carbs helps a lot for me. But I can' t keep to it very well without the adderall unfortunately.

This point you made about imbalance in leg muscles has just illuminated a possible source of my back pain that should have been obvious to me but I just attributed it to age. My left leg is weaker than my right due to knee surgery I had a decade ago. My muscles never fully recovered and now I have back/leg pain on my right side. I will have to look into correcting this and see how my pain progresses over time.

It should go without saying that YMMV if you keep that up.

This is false. The PCAT is required by most schools.

when I visited 6 months ago, a face scan was required to enter the country, so they're going to get it either way.

Just for more clarity then:

62.7 million Americans don’t have smart phones

82.5 million Americans don’t have credit cards

33 million Americans use only cash

Another way to look at it

The equivalent of the entire population of the United Kingdom not having smart phones

The entire population of Germany not having credit cards

Nearly the entire population of Canada using only cash

I agree with this opinion fully and I find it odd that the OP you replied to doesn’t call for the federal agencies that were conducting unconstitutional surveillance to be held accountable in court?

umami has been replicated over and over, along with texture, it's not special

I was never arguing against their point

your wording indicates it is a guess, giving a specific percentage wouldn't have doxed you