noyeastguy

For me, the diet puts HS completely into remission. I've been on the yeast and wheat-free diet for about six years. While the diet is hard to follow, I never have any boils, sinus tracts or any skin inflammation. Also happily (and anecdotally) I no longer experience headaches or migraines of any kind.

I follow a yeast-free diet to control an auto-immune disease called Hidradenitis suppurativa. Some doctors produced a study a while back where they found anti-Saccharomyces cerevisiae autoantibodies in HS patients. When patients followed a yeast and wheat-free diet they would see 100% remission of symptoms. The hardest part of following this diet is avoiding yeast as it is a major flavor component in almost all "ultra-processed foods", especially the "healthy" ones. Vegan and plant-based foods add yeast proudly. The problem is that our bodies have an innate immune system that is coded to recognize and fight fungi. Our DNA even codes for pattern recognizers that specifically target saccharomyces cerevisiae, also known as bread/baker's yeast. It's alarming to me that scientists know with certainty that yeast is innately inflammatory, and that inflammation is the majorcause of chronic disease, but have not put it together that maybe yeast should be avoided as a food additive.

Thanks for providing some scientific literacy to my argument. The western diet is designed around eating fatty foods wrapped around some innately-inflammatory bread product. If I was trying to give myself arterial plaque I would eat something that causes inflammation (yeast) and at the same time eat lots of fat. It boggles my mind how researches have failed to synthesize that yeast is the cause of so much disease.

Sure. But what is known about atherosclerosis is that plaques are not _on_ the arterial wall, but _inside_ the arterial wall. For plagues to form, fats have to be pulled into the arterial wall. How does this happen? Inflammation as designed opens up the arterial wall as a way to allow immune cells passage. Atherosclerosis happens when you have a bunch of fat in your arteries and you open them up to go inside. That's why cheeseburgers and pizza are the perfect heart disease vectors (Western diet). The bread parts cause inflammation via innate immunity (saccharomyces receptors) and the saturated fat parts (cheese and meat) flow in.

https://pubmed.ncbi.nlm.nih.gov/18163971/

I support this as an avid DDG user. Russian disinformation is a new kind of warfare that we've not inoculated ourselves against yet. This is a step in that direction. “in order to maintain a tolerant society, the society must be intolerant of intolerance.”

The sad reality is that people will die from the excess carbon and pollution put into the atmosphere by mining crypto.

This will be an interesting experiment to see what happens when these companies spurn the customers that created the conditions for this market to exist. I hope Apple or another company is smart enough to use this opportunity to scoop up disenfranchised customers and let AMD and NVIDEA waste more time serving the Ponzi industrial complex.

It sucks that people can't purchase GPUs to fill real needs because an illicit need for has been found for them instead. We now have an actual value lost in our civilization so that people can be separated from their money in an investing facade. I wish the pump and dumpers would move back into penny stocks and not waste electricity and GPUs.

https://www.merriam-webster.com/dictionary/illicit "In any case, illicit may be used of behavior that is either unlawful or immoral."

Putting carbon into the atmosphere (to the detriment of unborn people) in order to circumvent the laws of society and intentionally create a speculative bubble meant to pray on the unsophisticated investors and rob them of wealth is the definition of immoral behavior. Cryptocurrency was designed to disrupt laws (and has been used, see selling drugs on crypto, ransomware), so it must also be considered unlawful.

This would have to be a shallow definition of illicit. I think wasting energy, hoarding GPUs, baiting unsophisticated investors could be all be considered illicit activity. By that definition all of cryptocurrency is illicit.

I would like to see a new web with a reduced feature set. Something like web 1.0 pages but with only semantic tags like RSS. Remove the ability to create user interfaces and forms. Could we build a spec for this new WWW and create a way for it to crawl and search RSS at the same time? It's time to go backwards. We lost the good Internet along the way to getting the crap we have today. Let's build Web -1.0

It seems like there is some new undetected "lead in the pipes" thing going on these days where everyone is going crazy. Sociopathy is running amok. Our institutions used to be able to control these people. We need new ways of identifying bad actors and marking them to the rest of society. Maybe with Elizabeth Holmes getting found guilty the trend can start reversing. Hey you know what? Maybe we could create a trust-less distributed database to keep track of conmen, like a Equifax for bad actors on the blockchain ;).

I think it would be cool to imagine ourselves as part of the process of civilization that created these buildings and restore them to their former glory. If the Mona Lisa was ripped in half we would surely restore it back to a single piece. Why should we not rebuild ancient Rome and host pop-up shops and events in the Forum?

I wonder if there will come a time when society decides it's better to fix ruins such as the Colosseum and the pyramids instead of letting them just rot away.

I'm just saying that a wheat and yeast-free diet has reversed Hidradenitis and many systemic inflammation symptoms for me. In trying to understand _why_ it became clear to me that yeast (and maybe wheat) trigger an inflammatory response in our innate immune system - by design. So it's probably not a good idea to eat yeast unless you want to up-modulate your immune system (inducing inflammation). Even if your body can down-modulate, isn't that just causing a sensitivity imbalance similar to diabetes and glucose?

For example, Dectin-1 is one of many innate cellular receptors that launch inflammatory responses when Bread yeast (and others) is detected (and possibly 1,3 beta glucans from wheat). We are in a genetic war with saccharomyces cerevisia, inside of our DNA. And not just us, all animals need to be in this war, because otherwise we'd die.

https://en.wikipedia.org/wiki/CLEC7A

So if all this is true, does it make sense to put yeast extract in your gravy tonight?

Yep, it's kind of a double-edged sword. On one hand an over-active immune response can be great for fighting cancers and opportunistic infections possibly. But too much inflammation will wear down our bodies and trigger auto-immune responses.

This diet is hard to follow because yeast cuts through a lot of foods, especially in fermented foods as you've mentioned. A non-exhaustive list of yeasty foods looks like: Non-distilled vinegars, non-distilled alcohols, dried fruits, naturally-fermented soy sauce, cheese, many savory packaged goods, most vegan meat replacements, some dried spices, bread, etc.

Fermented foods and mushrooms can be good at fighting cancer precisely because they ramp up the immune system. In fact yeast is used as an adjuvant inside of vaccines for this purpose.

What's insane is that it is both known and not known that yeast causes inflammation by science. Used as adjuvant, used to "boost" immunity, yet not understood to be a cause of general low-grade systemic inflammation when in our food supply.

Opportunistic Strains of Saccharomyces cerevisiae: A Potential Risk Sold in Food Products https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705302/

I absolutely agree with this. My great grandmother had Alzheimers as well as Hidradenitis suppurativa, which I have inherited from her. I switched to a yeast and wheat free diet many years ago to relieve symptoms of HS. Not only did it resolve my HS, but also migraines and many other inflammatory issues. Looks like there is research around Alzheimer's and Dectin-1 signaling which is involved in innate immunity to fungi, including bread yeast (Saccharomyces cerevisiae). It's absolutely insane to me that people eat a pathogen that triggers an innate immune response. A inflammation response to yeast is coded into our cells, if it weren't we'd be killed by unbaked bread. Why then do most processed foods contain it? We're taxing and confusing our immune systems by eating it.

Munger obviously cares for young people and education if you read or listen to him. I feel like the people complaining about economical living conditions are going to turn around and propose erasing college debt, without ever addressing the cause. This is one way to make college more affordable and allow students a better chance of meeting people.

I used to get aura-style migraines. After following a yeast and wheat free diet my migraines went away. I started on the diet based on a small study as a way to suppress hidradenitis suppurativa symptoms. I’ve now been on this diet for 7 years and have not had a single migraine. It’s clear to me that the cause of migraines are inflammation, in my case caused by innate immunity (with a failure to down regulate) to fungi and 1,3, 1,6 beta glucans.

I believe that people with hyperphantasia can actually visualize chess boards on ceilings. As somebody who cannot actually visualize things with my mind’s eye (aphantasia) I cannot comprehend this.

I suspect that there is some truth the the "Chinese-restaurant syndrome" beyond the racism of the times. Chinese food contains much soy sauce and other fermented ingredients. These foods contain yeasts which are naturally inflammatory via multiple innate immune system pathways. MSG is even produced via fermentation but is probably more devoid of yeast and bacterial cell wall polysaccharides than other ingredients. Inflammation is most probably the cause of these mysterious headaches that are reported.