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niekmaas

488 karma · joined October 13, 2009

MD PhD in (computational) pathology and tumor biology. Lifelong geek and programmer. Working on www.summarized.science to make my (and yours?) life easier.
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niekmaas··on Medical students are using popular research tool to pump out misleading studies
Well, that is a statement..! As an MD PhD with over 60 (co-)publications including multiple in top 1% journals I can say for sure that this is untrue. Of course this may be different per topic and country, but there is perfect research being published by non-PhD scientists. In fact, the PI from a top-tier US university I collaborate with for over 10 years doesn't even have a PhD.
niekmaas··on Ask HN: What are you working on? (January 2026)
Well, you're absolutely the target audience. As you can see my focus so far is mostly on (neuro) oncology as this is my domain of interest/work. Let me know if you have any topic requests or have any ideas for additional features to make our lives as medical specialists/researchers easier. Contact form is on the site or just email whatever to the domain (catch-all doing the work).
niekmaas··on Ask HN: What are you working on? (January 2026)
No problem, and thanks for the request! #insulin-resistance is now added: https://www.summarized.science/topics/insulin-resistance/ . I ran it for each month of 2025, if you want to go back further just let me know.

Adding personalised highlights of topics of interest into the monthly emails is my top priority for 2026. Won't be too complicated, just have to set up the right API back-and-forths etc.

Good point about deep dives. I could do that for the topics I'm an expert in, however, by definition, I think this requires domain expertise and is therefore not scalable nor to be automated easily. I'm not sure if this fits the scope of the current project as I want people to find the papers of interest, read a quick summarization and then encourage them to read a selection of papers themselves.

niekmaas··on Ask HN: What are you working on? (January 2026)
As a pathologist and neuro-oncology researcher, to save myself time trying to keep up with scientific literature, I'm working on https://www.summarized.science/ . Based topics of interest (suggestions are more than welcome), the tool queries the scientific literature for each month. Then, by quering some LLMs, it extracts themes and summaries. The tool already saves me time in my day to day life, but still needs a lot of finishing touches to promote actively. Anyhow, it is a lot of time working on a web development "side project" after a hiatus of more than a decade due to residency/PhD-program/kids etc. Input/feedback is more than welcome.
niekmaas··on Ask HN: Companies hiring for a 4-day workweek?
Depends on the industry/company but for me it works like this: when the holiday is on a Friday (my day off) it's bad luck and I don't get an extra day. Simultaneously though, when I have to go to a specific conference on a Friday I can switch my day off to a different day in that week since then I will be "forced" to work on my day off.
niekmaas··on A man who accidentally started an assassin hiring website
There is no way for us to know if the drug is a "revulotionary cancer drug" if we don't test it in a double blinded randomized controlled trial (RCT). Indeed it would be disappointing the later find out you were treated with the placebo, but so many drugs or other interventions have to potential to be revolutionary but fail to really change the clinical decision making later on.
niekmaas··on UK Covid: Under-30s offered alternative to AstraZeneca jab
Excellent point. One thing I notice in the discussion about AZ is the fact that the risk for thrombosis is not really put into context. One very strong comparison is this: when taking a 6-hour flight the risk for thrombosis is about 5 times higher than the risk currently associated with the AZ-vaccination (ref. https://pubmed.ncbi.nlm.nih.gov/17351849/). Still most of us will happily board a plane once this is possible again. I'm not saying we shouldn't be critical about side-effects associated with the AZ-vaccine, I'm just missing a bit of context.
niekmaas··on Modern Text Features in R
I think the appeal to the tidyverse "universe" is the readability of the code. Especially to novel users of R (and there are a lot of people in science that have to generate a plot once a month or so). ggplot2 works fine if you only use that package without the rest of tidyverse. I personally use the data.table package a lot and than generate plots using ggplot2. Stackoverflow is indeed very much focused on tidyverse packages which is a pity as indeed base R can solve so many problems posted too without the need of additional packages.
niekmaas··on Ask HN: Something like Khan Academy but full curriculum for grade schoolers?
Perhaps aimed at a lower age group, but I think https://www.e-learningforkids.org/ should also be mentioned. They provide free primary school education for all kids. Currently mostly focused on math though.
niekmaas··on Show HN: Ratemydorm.com
Is there any validation that the user is actually from the selected college? It seems I can write a review about a random dorm just by selecting it. What about using the student’s .edu email address to validate the submission? Just a validation code in the email should be enough. Good luck on the launch though!
niekmaas··on Biomedical superstars are signing on with Google
"My hunch is that Google has a oncology/immunology platform"

As an MD, soon to have a PhD in oncology immunology, I always wonder what project Google could be working on in this area. After all they are a company and most probably try to develop products that will yield a return in the future. So why would someone chose to work for a Google firm that has no real track record in the Life Sciences versus the many life-science companies that already have amazing logistics/experience in place (Novartis, Biogen, Takeda to name just a few in Cambridge, MA). Outside "data-science" projects like genomics, or very technical project like lab-on-a-chip devices, I wouldn't see a big advantage moving to the bay area. However, I guess offering huge salaries always helps convincing people to join your company. And the winters in the Mountain View are probably warmer than the Boston area.

niekmaas··on Cofactor Genomics (YC S15) Pursues RNA Testing, Offers Better Diagnoses Than DNA
Finally a topic on hackernews that I am getting my PhD in..! Anyway, do you have any data indicating what percentage of circRNA is "free" in the plasma versus inside of other entities like platelets or extracellular vesicles (exosomes)?
niekmaas··on Numbers That Explain Why Facebook Acquired WhatsApp
I assume they have to pay taxes over this.
niekmaas··on Questions People Ask When I Tell Them I Own an Airplane
A private pilot license (PPL) does not allow for commercial flying (charging passengers). To charge passengers to pilot requires a commercial pilot license.
niekmaas··on 9,866,539 buildings in the Netherlands, shaded according to year of construction
Very far for Dutch standards of course. Maastricht is only 2-2.5 hours away from cities like Utrecht, Amsterdam and Rotterdam. For other countries this would be considered close neighbors.
niekmaas··on Norwegian lawyer had visa withdrawn after private chat with client on Facebook
In The Netherlands a case is usually dropped if evidence is provided that the conversation between a lawyer and his/her client was recorded and analysed.
niekmaas··on Breaker 101: An intensive online web security course
This book covers a lot of the material: http://www.amazon.com/The-Web-Application-Hackers-Handbook/d...
niekmaas··on How to invite users to your app
Is it really needed to have a 1226 x 515 px header image for a blog? I understand that some of the readers are using the latest "retina" Macbooks or 52-inch displays, but on my couple year old Macbook I can just see the top of the title when loading this page.
niekmaas··on What happens when you are the doctor on the airplane?
Out of hospital CPR has very slim survival chances. Being on a plane will result in at least 30 minutes of CPR even before an ambulance can take over. Chances on surviving that are extremely low. Therefore I can see why the doctor on the plane decided not to perform CPR. I have a medical degree myself btw.
niekmaas··on Texas School District will let Teachers carry Guns
Now we only have to wait for the respons of the "attacking gunmen"... will they increase their firepower? Body armor? Hand grenades? Tanks?

Fighting violence with violence will only result into more victims!

niekmaas··on With More Than 20M Gamers Tuning In, Twitch Raises $15M
I've heard that argument about Korea ever since I started following and working in eSports (around 2004ish). Yet, I'm still waiting on that big breakthrough in the USA/Europe. I'm afraid it will still take quite some time.
niekmaas··on StickyMojo: A contained sticky sidebar plugin for jQuery.
Why is there need for a plugin to do this? Why not use CSS: position: fixed?
niekmaas··on Have you ever chatted with a hacker within a virus?
Perhaps a rather naive questions, but: were the username and pw transfered in plaintext?
niekmaas··on 6.5 Million LinkedIn Password Hashes Leaked
Why would you use the email? Mostly when passwords/usernames are stolen the email is there too. For my site I have an unique 128-bit token for every user. I also have a 128-bit site_key (which is in the application, not db) and mix those with the password and then hash.
niekmaas··on Yammer CEO won't hire anyone from Yahoo who doesn't quit in next 60 days
And worse, the whole layout is a Facebook ripoff. My girlfriend uses Yammer for work and when I took a closer look at it today it seems that most of the IU elements are 1 to 1 copies of Facebook. Pretty sad to be honest.
niekmaas··on Ask HN: What will happen to Google when somebody disrupts AdWords?
Of course this will likely happen when a decent alternative presents itself. This is not guarenteed to happen though. The same could have been said about 'search' when Google wasn't around. 'Yahoo will buy them'. They had the chance but did not see the potential Google had as a searchengine. Whith this in mind it could potentially happen that a new company comes up with a better idea and grows too big too fast for GOOG to buy them. But that's the whole idea behind investing in the stock market: past revenues are no guarantee for the future...
niekmaas··on Airbnb Victim Speaks Again: Homeless, Scared And Angry
How does this work legally? Is it still burglary when the people were allowed in the house? Of course taking things that do not below to you is theft. But going through someones documents, is that illegal?
niekmaas··on Thousands of scientific papers uploaded to The Pirate Bay
For most journals I have experience with as a (co-)author a signed form is required for every (co-)author on the paper. This way it's pretty hard to deny you have knowledge of the paper.

I agree with you that people that have not contributed should not be on a paper. For most high impact journals thesedays explanation is required of who did what. Of course this is far from 100% secure but it's an interesting step. Lying about the contribution of a certain co-author is something else than just adding a name to the list. Lying is fraud whereas adding a name might not actually be fraud I think.

niekmaas··on Dotjs — hack the web
don't forget the cloud!
niekmaas··on Skills a Designer Must Have when Working for a Startup
The word "startup" has almost reached the status of buzzword. "Cloud based startup" would have been even better..
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