205 karma · joined August 31, 2011
GRRM on the other hand agonizes over writing out perfect rough draft pages and thus never gets anything done.
That's the whole point of HBO. Entertainment that at least tries to be high quality. Will succession meet that mark? No idea, they're only one season in. But if they fail they will not be the first hbo show to do so.
The ice age will end when the large ice sheets still covering land are gone. That's mostly Greenland. At which point the world will be a total mess.
Or the train is being removed from service. That's not really going to happen in the middle of the night but definitely happens during times when they are decreasing service (after rush hour, after like 11pn)
So really you need to be trusting that they are responsible enough to take their drugs every day. These days that is pretty easy, most people take 1 pill in the morning and that's it.
You'd normally want to be UD for 3 months before engaging in unprotected sex with your informed partner.
Not sure if that's the part you're having a hard time with or not.
A subset of the population will become resistant to certain classes of drugs, because people do stop taking drugs etc. And gain resistance, then pass that on, but for a specific individual their current regimen should be good for as long as they take it. Realistically people change drugs every so often as better drugs with lies side effects are released, but not because of new resistance development.
Now this did used to be a bit if an issue since people had to take multiple pills at different times a day. Having to do that makes missing doses easier, and then resistance can develop. But these days most people are on a single pill taken once a day that completely eliminates that risk.
You're thinking of this like antibiotics, when it's really not a comparable situation.