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kken

1,568 karma · joined January 3, 2013

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kken··on Philly scientist behind COVID vaccine tech was demoted by UPenn
This is actually quite a good background story on the mRNA COVID-Vaccines, that also explains Karikós role in more detail.

https://www.statnews.com/2020/11/10/the-story-of-mrna-how-a-...

WSJ also has a number of good articles:

https://www.wsj.com/articles/how-pfizer-delivered-a-covid-va...

https://www.wsj.com/articles/how-a-couples-quest-to-cure-can...

https://www.wsj.com/articles/how-pfizer-partner-biontech-bec...

What I found quite interesting was the latest news release from BioNtech where they thank all their partners. Some parts of the supply chain are only served by very small companies.

https://investors.biontech.de/news-releases/news-release-det...

kken··on Open Source Smartwatch
Nice!
kken··on Open Source Smartwatch
Ok, just to make sure I understand this correctly.

- This is basically a commercial smartwach (the Colmi P8) that is based on a well documented SOC, the nordic nRF52832

- The open source version comes with an enclosure that is not glued shut, so that it is easy to access testpoints on the pcb.

- Development is done by accessing the nRF51 SWD interface with pogo pins or similar. The programming interface can be a standard SWD interface such as an STLink clone

Ok, sounds easy enough. It should be possible to just buy one of those smartwatches and crack them open? But OTOH the developer version is not much more expensive.

The main question is now: What software to run on it, that goes beyond a few experiments? Is there any kind of open source smartwatch OS that would run on this?

Edit: Corrected typo, of course I meant SWD interface, not SWM. (SWM or rather SWIM is for STM8)

kken··on Metal Monolith in Utah Gone
This was definitely dated back. Maybe by changing the EXIF information?

Note how there are many fingerprints on the monolith that only appeared after many people visited it. They cannot be seen on the early photos from right after the discovery.

kken··on The Lucrative Art of Chicken Sexing (2017)
FYI, there is a German company who have developed industrial processes to determine the sex of a chicken before it hatches

https://www.seleggt.com/seleggt-process/

It's already being used in you can buy eggs from hens sexed with this method in the supermarket.

Video of the machine: https://www.youtube.com/watch?v=OeAWcF1MxNo

kken··on I was excited for Neuralink, then I watched the demo
> “So in summary I would say this is solid engineering but mediocre neuroscience. Finally, I think it is unfortunate that they are presenting their work in this way, rather than publishing peer-reviewed papers that would allow their claims to be scrutinised, but I guess this is something that we will have to get used to as neural interfaces move from the academic to the commercial sector.”

Well, and this is exactly what needs to be done to further this area as it is the part that's not completely addressed by academia. Any kind of academic research obviously focusses on generating one-time results for publication.

kken··on Springer Nature open access agreement and Elsevier update
Have you heard of the Journal "Nature"?
kken··on Springer Nature open access agreement and Elsevier update
Generally this sounds like good progress!

>Under the agreement, all articles with a UC corresponding author published in more than 2,700 of Springer Nature’s journals will be open access by default, with the UC Libraries paying a portion of the open access fee on behalf of all authors. Authors without available research funds for the remainder of the publishing fee can request that the Library cover the entire amount. Authors may also choose to opt out of open access publishing if they wish.

However, this seems to be severely limiting. So basically all research projects have to redirect funds to cover part of the "open access fees" or they have the dubious option to "opt out". The library only being willing to pay on case-by-case base means that there will be hidden disincentives in place.

Essentially that means that projects that are not willing to pay money to SpringerNature will be at a disadvantage.

I wonder which mechanisms were implemented to prevent them from arbitrarily increasing open access fees? This is conspicuously absent from the article.

kken··on 'Quake III Arena' Bots Decide to Stop Fighting After 4-Year Match (2013)
So it is a forbes article that is based on an imageboard screenshot. I have seen more reputable sources...
kken··on Trump and Chip Makers Including Intel Seek Semiconductor Self-Sufficiency
This is something that happened in the 70ies. The industry has come a long way since then.
kken··on German man living at Delhi airport since March 18
This is the real reason he is stuck.

> "He added that because India did not give Ziebat a visa due to his criminal background — criminal offences are taken into consideration when assessing individual visa cases in India — he remains unauthorised to leave the airport’s transit area. In India, an international passenger can normally stay in transit for just one day, and requires Indian visa to step out of this designated space for travellers passing through the country. The officer added that Ziebat has also not formally applied for an Indian visa."

kken··on Germany and US wrestle over coronavirus vaccine: report
The timeline of their press releases is interesting, to say the least:

https://www.curevac.com//news

03-03-2020

CureVac CEO Daniel Menichella Discusses Coronavirus Vaccine Development with U.S. President Donald Trump and Members of Coronavirus Task Force

03-11-2020

Company Founder Ingmar Hoerr Succeeds Daniel Menichella as CEO of CureVac AG

03-15-2020

CureVac focuses on the development of mRNA-based coronavirus vaccine to protect people worldwide

kken··on Undocumented CPU behavior: analyzing undocumented opcodes on Intel x86-64 (2018) [pdf]
Think more! One would guess that the search for undocumented opcodes yields results...?
kken··on Undocumented CPU behavior: analyzing undocumented opcodes on Intel x86-64 (2018) [pdf]
It would actually be interesting to see examples of actual undocumented opcodrles. There are none in the linked article.
kken··on What made the 1960s CDC6600 supercomputer fast?
>MOS is just hard

I think the important point is that "MOS scales". All the bipolar technologies never had anything like Dennard scaling, which was the backbone of Moores Law.

kken··on What made the 1960s CDC6600 supercomputer fast?
Some of Crays speeches are available on Youtube

https://www.youtube.com/watch?v=8Z9VStbhplQ

The Q&A section is quite interesting. His knowledge of technical details is very impressive and you can feel the tremendous amount of respect that was bestowed on him by the audience.

kken··on Ask HN: What technology would you bring to the world, Manhattan-project style?
One obvious answer may be controlled nuclear fusion. But then you realize that the manhatten project was not very expensive ($23B in todays money) compared to the current efforts on fusion like ITER ($20B).

Unpopolar opinion: Maybe the Manhatten-Project, the fission bomb, was actually not that difficult compared to other challenges that are ahead of us?

kken··on Demoscene, the secret behind Finnish game industry
Don't forget Falanx from Norway. They were acquired by ARM, turning into the Mali GPU.
kken··on “You're stealing our water”: Germans protest against Tesla gigafactory
Doesn't Tesla already heavily rely on "German engineering"? They have/had plenty of executives from German automotive companies, they own an automation company in Germany and their supply chain probably has many German companies in it. (Three of the Top5 automotive suppliers are German)
kken··on “You're stealing our water”: Germans protest against Tesla gigafactory
These are just your run off the mill NIMBYs. Many of those are way past their employment age, just take a look at the pictures. There was also a counterprotest.
kken··on A tiny RISC-V MCU board selling for $3
As already noted in the comments under the linked article: This device is currently seriously lacking software support, bordering on making it unusable.

It's interesting to note that the company that developed the chip (Gigadevice) initially got big by copying microcontrollers by ST microelectronics. This went as far as copying the entire product portfolio including naming scheme and marketing strategy. (Personally I find this absolutely appalling)

I guess not having to develop a software toolchain for their devices provided a huge benefit for them. Now that they have a device that cannot rely on external tools, things look a bit more difficult...

kken··on A look inside TSMC
When I read the title, I was actually hoping for a video tour of one of their fully automated 300mm Fabs.

Unfortunately it seems that video material of cutting edge fabs on the web is scarce, and what is available does not really show the fab as a whole, but only details instead.

Well, I guess everybody is afraid of giving away IP...

Some examples:

https://www.youtube.com/watch?v=inoOAOOMjHo

https://www.youtube.com/watch?v=yaASEMAMCNM

https://www.youtube.com/watch?v=K_VIgU1hPok

Research labs

https://www.youtube.com/watch?v=b_PCQAJzHj8

https://www.youtube.com/watch?v=ttD7JOwpNXo

kken··on A look inside TSMC
Yes, it's ASML and their technology partners in Europe (Zeiss, Trumpf, many others).

ASML is really at the core of bleeding edge semi. Their lithography equipment is basically unchallenged in the industry. Noone can make a 7nm CPU without them.

kken··on Friends of Vast Industrial Concrete Kafkaesque Structures
Indeed, looks like the word is a bit misplaced here.
kken··on Bye, Chrome: Why I’m switching to Firefox (2018)
These articles always feel like i missed something. I have stayed with Firefox all the time, never switched to Chrome.

Why should I have switched to Chrome, again?

kken··on Real-space charge-density imaging with sub-angstrom resolution
You mean the DOI? It's at the bottom.
kken··on The “terrible” 3 cent MCU – a short survey of sub $0.10 microcontrollers
Maybe one of these?

https://www.emmicroelectronic.com/catalog?title=&term_node_t...

EM Microelectronics is actually not so obscure. They belong to the Swatch group and are specialized in ultra lower power analog and mixed signal circuit. Obviously, first for watches.

kken··on IEEE Lifts Huawei Restrictions on Editorial and Peer Review Activities
>Our initial, more restrictive approach was motivated solely by our desire to protect our volunteers and our members from legal risk

In other words: They overreacted, possibly biased by those in charge.

kken··on Tech companies and governments sign up to Christchurch Call agreement
More internet censorship?
kken··on In African Villages, Phones Can Become Ultrasound Scanners
Jonathan Rothberg should have enough money to invest of his own. He is behind several dna sequencing companies.
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