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kiterunner2346

15 karma · joined August 6, 2019

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kiterunner2346··on Poland will treat all Covid-19 patients with Chloroquine
Yesterday or the day before IIRC a fellow "WilsonPaige", https://news.ycombinator.com/user?id=wilsonpaige posted much earlier on Hacker News and, right in front of us, deduced that the combinationn of chloroquin + zinc lozenges would stop the covid-19 virus dead in its tracks. He announced it as such.

In return, ycombinator moderators hellbanned him and deleted some of his posts.

Now it seems WilsonPaige was right and everybody who contradicted him are, at the least, looking foolish and simply wrong.

kiterunner2346··on Chloroquine: An Effective Treatment for Coronavirus
Why did you delete most of wilsonpaige's posts? All he did is put two things together and come up with an idea that will apparently work. So he's kinda in Neils Bohr's situation with the hydrogen atom: it works, it only works here, I don't know why it works, but it works! Isn't that the essence of creativity?

Why the dunning and shunning? If the women in reasonable shoes on this bbs had any creativity we wouldn't be in a jam with Covid.

Is wilsonpaige so different in this regard from Elon Musk? Musk posts re quinone and is praised and his ideas spread. Wilsonpaige at first doubts the quinone solution, then within hours finds confirming studies, adds to it his experience with zinc antivirals and comes up with a better solution (albeit one w/o an underlying mechanism). Now you've torn his posts up and thrown them away.

Shame!

kiterunner2346··on Chloroquine: An Effective Treatment for Coronavirus
WilsonPaige is right (if not always for the "right" reason):

"Coronavirus Chloroquine & Zinc Treatment":

https://citycourier.org/news/coronavirus-chloroquine-zinc-tr...

kiterunner2346··on Get Real: no drug or vaccine will avoid a very big coronavirus epidemic
Lancet Article(February 22, 2020): "Reducing mortality from 2019-nCoV: host-directed therapies should be an option"

https://www.thelancet.com/journals/lancet/article/PIIS0140-6...

from the article:

"In most moribund patients, 2019-nCoV infection is also associated with a cytokine storm, which is characterised by increased plasma concentrations of interleukins 2, 7, and 10, ..."

kiterunner2346··on Get Real: no drug or vaccine will avoid a very big coronavirus epidemic
Title: "Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China"

https://www.thelancet.com/journals/lancet/article/PIIS0140-6...

from the Lancet article:

"In view of the high amount of cytokines induced by SARS-CoV,22, 24 MERS-CoV,25, 26 and 2019-nCoV infections, corticosteroids were used frequently for treatment of patients with severe illness, for possible benefit by reducing inflammatory-induced lung injury. However, current evidence in patients with SARS and MERS suggests that receiving corticosteroids did not have an effect on mortality, but rather delayed viral clearance.27, 28, 29 Therefore, corticosteroids should not be routinely given systemically, according to WHO interim guidance."

kiterunner2346··on Get Real: no drug or vaccine will avoid a very big coronavirus epidemic
The key may not be a vaccine but simply staying alive. Covid-19 kills with a "cytokine storm":

cytochine release syndrome(cytokine storm):

https://en.wikipedia.org/wiki/Cytokine_release_syndrome

Article discussing coronavirus et al and cytochine storm:

"Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China"

https://www.thelancet.com/journals/lancet/article/PIIS0140-6...

From the article:

"In view of the high amount of cytokines induced by SARS-CoV,22, 24 MERS-CoV,25, 26 and 2019-nCoV infections, corticosteroids were used frequently for treatment of patients with severe illness, for possible benefit by reducing inflammatory-induced lung injury. However, current evidence in patients with SARS and MERS suggests that receiving corticosteroids did not have an effect on mortality, but rather delayed viral clearance.27, 28, 29 Therefore, corticosteroids should not be routinely given systemically, according to WHO interim guidance."

Curcumin has been shown to suppress the cytokine storm.

https://www.ncbi.nlm.nih.gov/pubmed/25600522/

Curcumin is found in the spice turmeric and is available in most grocery stores. Today you can buy a pound of turmeric powder for ~$6. You can buy curcumin tablets in the health & fitness section.

Other anti-inflammatory agents (NSAIDS(aspirin, buprofen, naproxen),prednisone, etc.) are not as effective.

In India children are often given a daily teaspoon of turmeric (curcumin) in milk or water. India suffered much lower SARS deaths (there are confounding factors, e.g. India's high summer heat). I expect the same to happen with covid-19.

kiterunner2346··on Vitamin C and Immuno-Oncology
Years ago one doctor (IIRC a general practioner) noticed that all his diabetes patients taking metformin never got cancer. So he wrote a letter about it. I've lost the cite.

Today everyone, even doctors, knows that high blood sugar levels increase the odds of cancer AND diabetes. That's why everyone and his dog is taking metformin and why that drug is almost always the first ingredient included in "life extension" cocktail drug tests.

kiterunner2346··on How Many Push-UPS Can You Do? It May Be a Good Predictor of Heart Health
"...The results suggest that push-up ability might be a simple, reliable and D.I.Y.-in-your-living-room method of assessing heart health..."

I call BS. Body weight exercises like push-ups are more difficult for taller people.

<sarcasm>A a better predictor of heart health might be how quickly you can clean the top of the refrigerator. </sarcasm>

kiterunner2346··on Toxic sofas are a secret scandal
carapace says>"Little rings of gunpowder in the paper to make it act like a fuse..."

There is no gunpowder in cigarettes:

https://www.verywellmind.com/big-tobaccos-list-of-599-cigare...

https://boards.straightdope.com/sdmb/showthread.php?t=27857

A non-addictive cigarette would have to have no nicotine b/c nicotine is addictive:

https://www.drugabuse.gov/publications/research-reports/toba...

"Source: A long time back a friend of mine's brother was part of a faux-jury assembled by tobacco company lawyers to do like a focus group to research how real juries in some real trial might think/feel."

Ycombinator post<--carapace<--friend<--brother<--faux-jury<--lawyers<--tobacco company

Even facts get changed when they're nested >5 levels deep in human networks.

kiterunner2346··on Common Sense for the 21st Century (2019) [pdf]
I prefer David Deutsch's optimistic approach to our problems: use science to find solutions. Rebellion is beyond the pale. We don't need rebels; we need scientists and more good science.

"The Beginning of Infinity: Explanations That Transform the World" by David Deutsch

https://www.amazon.com/Beginning-Infinity-Explanations-Trans...?

kiterunner2346··on Gilbert Strang Teaches Linear Algebra
Is there a text focusing on the known differences between the lower dimensional spaces of 1-4 dimensions and the higher-dimensionality spaces commonly used in DNN calculations?
kiterunner2346··on Ask HN: Which browser is your default, and why?
What a great analysis and reveal. Thank you!
kiterunner2346··on Ask HN: Which browser is your default, and why?
thecupisblue >"...previously was a Chrome and Opera (but never again after I learned what the f is going on there)."<

What is going on there?

kiterunner2346··on [dead]
Phone the FBI and tell them. They will set you up with a new identity and tell you how to stay hidden.
kiterunner2346··on New coronavirus can spread between humans, but started in a wildlife market
"Did China Steal Coronavirus From Canada And Weaponize It?"

https://www.zerohedge.com/geopolitical/did-china-steal-coron...

From the article:

"In March 2019 ... a shipment of exceptionally virulent viruses from Canada’s NML ended up in China. The event caused a major scandal with Bio-warfare experts questioning why Canada was sending lethal viruses to China. Scientists from NML said the highly lethal viruses were a potential bio-weapon.

Following investigation, the incident was traced to Chinese agents working at NML. Four months later in July 2019, a group of Chinese virologists were forcibly dispatched from the Canadian National Microbiology Laboratory (NML). The NML is Canada’s only level-4 facility and one of only a few in North America equipped to handle the world’s deadliest diseases, including Ebola, SARS, Coronavirus, etc."

kiterunner2346··on Ask HN: What’s your most imp life lesson that you wish learned 10 years earlier?
Lesson learned years after middle- and high-school: most everybody (even those you know) is having sex (but you aren't)!
kiterunner2346··on The Basic Problem of Democracy (1919)
I think it relevant to mention Lippmann's statement on Congressional investigations:

"So bad is the contact of legislators with necessary facts that they are forced to rely either on private tips or on that legalized atrocity, the Congressional investigation, where Congressmen, starved of their legitimate food for thought, go on a wild and feverish man-hunt, and do not stop at cannibalism. "

p. 6, PUBLIC OPINION (1921) by Walter Lippmann

http://wps.pearsoncustom.com/wps/media/objects/2429/2487430/...

kiterunner2346··on Can a row of five equilateral triangles tile a big equilateral triangle?
Sure, if the smaller triangles are allowed to overlap.
kiterunner2346··on Learn Coq in Y Minutes
Ummm, so how is "Coq" pronounced?
kiterunner2346··on Vinod Khosla Wins Ruling Threatening Public Beach Access
option says>"I did not join Theranos after looking at their board."

I had to look up Theranos to understand this. I somehow feel dirty.

kiterunner2346··on The Real Class War
Capitalism can't do that without redistribution in the form of severe taxation of the wealthy. That's why we need to revive estate taxes and inheritance taxes: in their absence, great dynasties of incredible wealth are formed and then sit idle for decades or even centuries, protecting themselves in trust fund fortresses to no particular end than their own existence.
kiterunner2346··on The Real Class War
Could someone write a tl;dr for this article so I can understand his point(s)?
kiterunner2346··on PayPal stops payouts to models on Pornhub
"...Pulls Out..."?!

An improper metaphor since it was the performers who got screwed, not Pornhub.

But, in the end, Pornhub _will_ be screwed (no pun intended).

kiterunner2346··on Edward Snowden on The Joe Rogan Experience [video]
tfandango says> "If I see something and call that number, my identity will be protected. That is the way my company would prefer I handle ethical issues and I will keep my job. If I gather up evidence and release it to the press, I will lose my job."

Do NOT believe that!

The reality is probably quite different. Many organizations (both private and civil) make such promises but, in truth, the complaint phone line/box/e-mail is a direct line to either higher-ups in the company or to someone in another agency who will, very quickly, pass identifying information to higher-ups. The whistleblower will be tracked down mercilessly and driven out always. Those for whom the whistle blows will, not infrequently, be rewarded.

Sorry to burst your bubble, but I've been in many public and private endeavors and, in every case, so-called whistleblower phone lines, complaint boards or monitoring companies have proven to be ineffectual and/or downright deadly to the career of anyone who contacts them. They are usually honeytraps for those poor individuals who believe their complaints will be fairly judged.

With reasonable care the press can be relied upon to vent complaints to the public w/o identifying the complainant.

kiterunner2346··on The outcry over deaths on Amazon's warehouse floor
I've taken Amazon's warehouse guided tours several times The surprise was that there is NO surprise: the entire process is merely the application of current technologies in warehousing and distribution, with humans in the few niches where machines are not quite "there" yet. in the places where humans are involved, there's just enough workspace so that, say, once Amazon develops a proper "binning" robot, the human can be fired and a machine rolled in to replace him/her.

Place was nicely put together though: all the screws and bolts tight, racks and tracks level and properly aligned, sensors everywhere on the production line ready to alert of any problem. So kudos to the guys and gals who put it together and lined it up! Looks like the U.S. Army put it together (well, actually, if the Army did it, it would be use better parts and be more sturdily constructed).

As for what it does, nothing there of interest to high tech.

kiterunner2346··on Sears Hasn’t Fared Better After Bankruptcy
Never heard of "Mavis Discount Tire"! I Google'd "Mavis Discount Tire vs Discount Tire" to find that the latter is suing the former for trademark violations:

https://news.bloomberglaw.com/ip-law/discount-tire-lawsuit-c...

Wheel retailer Discount Tire claims a rebrand by Mavis Tire Supply LLC—labeling its stores Mavis Discount Tire—violates its trademark rights.

The company’s Dec. 26 lawsuit says Mavis started renaming stores after buying multiple chains located in the South and Midwest, where Discount Tire does business. Mavis intends to confuse customers and profit from goodwill built up in the Discount Tire trademark over decades, according to the complaint filed in the U.S. District Court for the District of Georgia.

Mavis previously used Mavis Discount Tire branding only in northeastern states with no competing Discount Tire stores, according to The Renialt-Thomas Corp., Discount Tire’s corporate name.

Looks like an interesting case!

kiterunner2346··on Ask HN: Is ML/AI a good long-term career path?
No, b/c there is no "long-term" for ML/AI. Look at what brought the current ML explosion: Moore's law held just long enough to make ML work reasonably well w/in the human attention span. Nobody anticipated this. It overrode other interests and now dominates AI (for the moment).

The same thing could happen again and another technology could sweep ML/AI aside. ML/AI itself is not a predictable "career path" like chemical, electrical/petroleum, or mechanical engineering are. ML/AI is more like the Wild West: maybe you're a wildcatter who has a new idea, thinks he can find oil and strike it rich.

If you want a predictable career path that covers most of the same subject area then choose statistics, mathematics or data science.

kiterunner2346··on Pizza robot makes 300 pizzas per hour
Yeah, but presumably it's cheaper, so Gresham's Law of Pizza demands that the better-looking pizza become obsolete.
kiterunner2346··on First detection of ringing of newborn black hole: Testing the no-hair theorem
It all began with Astronomer John Wheeler, who coined the term "black hole" nearly 50 years ago, and who famously said that "black holes have no hair" because of their simplicity.

"Hair" is used as a colloquial term among physicists as a stand-in for any other measure needed to describe a black hole, apart from the traditional three-quantity model: mass, angular momentum (how fast they spin) and electrical charge.

kiterunner2346··on The brain-heart dialogue shows how racism hijacks perception
Consider this hard fact:

"Blacks are just 13% of the population but responsible for a majority of all murders in the U.S...."

from the Wall Street Journal:

http://online.wsj.com/articles/jason-riley-the-other-ferguso...

One must conclude that, a priori, blacks are more dangerous that whites. Ergo, one would be wise to take fewer risks when engaging blacks in any way. This isn't necessarily racism, but merely common sense and one should not be surprised to find that, as the sinapticas article states(concerning policing):

"In prior studies, participants were significantly more likely to shoot an unarmed black individual than a white one."

Finally, to the above and other questions such as

"Do black Americans commit more crime?"

visit the url:

https://www.channel4.com/news/factcheck/factcheck-black-amer...

The answer is "Yes."

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