deugtniet

A placebo is not necessary in this phase (phase 0). The most important thing is that the vaccine is safe and that there is a dose dependent relationship. The placebo will only be necessary in later trial stages. Now it's mostly to assess safety and efficacy through immunological parameters.

Not much is known about the humans immunological response to covid or this vaccine. Derek Lowe is rightly pointing out that it's way too early to say if this is even effective against COVID. The safety and dose-dependency is just the first step in the process.

I don't think they implemented the `no ads before 8PM on tv` yet. I'm actually surprised about how open they are about advertising costs per second for each block on the npo1 channel [1].

[1] https://www.ster.nl/media/rrifn3t0/npo-1-juni-2020-gewijzigd...

Perhaps this is partly driven by COVID. A hotel is a great isolation facility. Having one for essential staff would be a massive benefit if you need them close by at short notice.

Based on the rules it cannot drop _more_ than 20% in a day :-)

There are examples of it happening in other countries though. Zimbabwe and Argentina come to mind for some crazy inflation and stock numbers.

Just to clarify the title:

Trading was halted for 15 minutes.

If you make things more expensive, less people will buy that thing. It will reduce emissions in the UK by reducing the airtraffic through the UK. Exactly the intended consequence.

France developed their own matrix protocol based network called tchap. Great idea for a nation that wants to stay independent in an increasingly american/chinese tech dependent world.

All you need to do is look at the health care costs per citizen of other developed countries to understand that the US is paying way too much in their current healthcare system. I'm aware that the US's healthcare system is unique in many ways, but so are all the other countries on that list and they made it work.

https://en.wikipedia.org/wiki/List_of_countries_by_total_hea...

> While I like the idea of traveling by train, and I even took a night train from Munich to Budapest in the past, but on that specific route I had to share my cabin with a guy who just got released from jail a day earlier so I was not pleasantly relaxed. The fact that the cabin only had 2 bunk beds and I was pretty much isolated from other passengers and I had no way to keep my money and other important things in a safe, made me worried a lot.

>The big advantage of air travel is exactly this, you don't need to spend much time in the actual plane. And the passengers are by definition under full-time supervision by other passengers, so stealing or attacks are not so easy to get away with.

There are also drawbacks to air travel that you're not mentioning. I was in a sleeping segment with 5 other people and felt more safe than in an airplane. The important thing though is: we need to cut down on carbon, and travel by train is an important way to do it.

Those are usually airport fees and such, I don't know where you get these numbers, but the airline pays the airport for the use of the terminal, baggage handling, air traffic control, etc.

This is different from tax, as without it you would not fly.

Last weekend, I took the night train from Briancon to Paris, step in at ~21:00, step out at 07:00 the next morning. My first time in a night train, pretty surreal but pleasant experience. I had to take a semi connecting train from Paris to the Netherlands (where I live), so it would be so awesome just to wake up on destination.

I'm considering if it's a good idea to tax air travel inside the EU to help the trains move forward. I believe air travel is not taxed at all. The resulting money could be spent on climate change reducing policies.

Testing somebody without symptoms is not accurate. Additionally, the current tests are very expensive and remove capacity for other individuals with symptoms.

It's called peace of mind. Some people worry about their privacy being violated. Without the sim, there is less tracking, so less to worry about.

Which is very normal state of affairs for research organizations. They try to reach as much of their employees / stakeholders as possible. You'd be surprised how often the work issued email address is not read.

I read this as an announcement of the 'why' they dropped it for their own 150 active users. There's nothing wrong with saying you stop something because it has become too expensive.

It's not price shaming, it's saying that you're not willing to pay the price that has increased. It would've been price shaming if it said that it was so much money for so little services.

Correct me if I'm wrong, but I believe the signal servers are hosted on google cloud, using encrypted traffic to obfuscate the point of exit for a signal user.

This is why in the past, governments were unable to block signal without blocking google or all google cloud customers themselves.

So as I read this, this is a device you have to carry next to your phone for your secure communications. Sounds interesting and for the security minded, it seems it could have some real added value. But for the average consumer it adds a layer of inconvenience that you don't want when contacting your grandmother. Are high powered individuals with strict security requirements the target market for this device?

School runs are done by bike in the Netherlands. In addition there are much more practical vehicles that farmers/builders/<insert_mobile_heavy_work_profession> use.

Professionally, I have not had to deal with a GDPR request luckily, as we have a lot of anonymized legacy data that is hard to track back to specific participants in our studies.

Personally, I feel the conversation on data in many organizations has helped me feel more secure in my privacy considerations. Although it may not be because of the GDPR, I feel I can make facebook/google/<data_aggregator> accountable about my personal information, if I really wanted to. Although I have not done it yet.

As the average HN consumer, I can get behind this.

It means that they don't want tracking to stop. And you should _definitely_ trust them as well as all their partners.

Good on Mozilla for doing this. I want privacy when I'm on the internet, without having to resort to tor-like schemes

bacteria =/= eukaryotes. Gene expression in bacteria is very far away from gene expression in humans.

My guess is the following: ASML produces the lithography machines, and TSMC/Samsung/<chipmaker> uses them in mass production. What I hear from the Dutch news is that the development process is very much a cooperation between different companies. What works in ASMLs lab will likely need a lot of tweaking before it can be used in mass production.

If you say something is a joke, and post an opinion through a music video. You cannot then claim your opinion is logical. Protestors opinions cannot be reduced to a joke without any explanation.

Except for the autofocus mechanics of course. Those move around before every shot...

Interesting to see that their test results are often very good (most of the NIST tests), but in certain other tests (Diehard Overlapping sums) there is p value inflation. I wonder where that comes from.

Really? How? What? Where? I honestly have no idea in what case / field the Chinese groups are miles ahead of anybody else in terms of genetics research. And I'm doing a PhD in the subject.

There are excellent groups in all countries, but in terms of superior tech on any side, I have not seen any.

There are great companies that facilitate genetics research, but the best tech in that case still is American (Illumina, Affymetrix, 10X genomics).

I think this is Microsofts way to limit legal, but more importantly, public image liability. These models can be used for bad stuff, like the profiling thats happening in <insert unethical organization/government here> right now. And Microsoft wants nothing to do with it.

I'm not naive about the limitations of the freedoms that are afforded to a citizen by the US government, or my government for that matter. We should have more freedoms and say into our government, and it should be more fair.

But here's the main point: It's a hell of a lot better than in China. Freedom and checks and balances are always on a spectrum. You're arguing that because there are limitations to your freedom, you might as well be totally in chains.

One point that I'm missing, is that the government of China can legally force any of their companies to start spying. And there would be no way that we would know.

Then often the argument becomes: But the US are already spying on us, so it's not too bad. Which is fair, but in the US, there are checks and balances and freedoms so that somebody has recourse. All these things are absent in China.

So the question is one of trust. Who do you trust more when they are spying on you: The US or China? For me as a European, this is definitely the former.