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brfox

755 karma · joined April 1, 2008

I work at a biotech company in Seattle.

contact me: ''.join(['b', 'andrew' , 'fox', '@', 'gmail.com'])

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brfox··on To my daughter's high school programming teacher
Yes, life is hard for girls and women and everyone else too with adversity.... but, I think some of the point of the article was that the teacher could have taught the boys something about how to treat girls and women. Set the tone right for them before they continue to engage in this behavior throughout college and adulthood so we can break this sexist cycle which is not present in many other technical fields.
brfox··on Funniest reviews
That is one of the 532 "Internet Memes" which I now need to read about: https://en.wikipedia.org/wiki/Category:Internet_memes
brfox··on Google not indexing Craigslist – SearchTempest switches to Bing
Because there are no Adsense ads on craigslist pages?
brfox··on Why the Fuck?
Very good points. I work as a bioinformatics scientist at Novo Nordisk, and we take our jobs very seriously in trying to find medicine for diabetes and other autoimmune diseases - and we feel lucky to have this possibility of success. It is very difficult because of many reasons, especially because each iteration (drug) takes years and costs millions of dollars to try out and hundreds of patients to volunteer to inject it into their body.
brfox··on Thank HN: Our friend is Safe and Sound
Original post asking for help:

http://news.ycombinator.com/item?id=4739649

brfox··on More in the series of bizarre UEFI bugs
This same exact thing happened to me earlier this week when installing a Ubuntu Desktop 12.04 LTS 64 bit on a new Lenovo ThinkCentre box. The only thing I could do was go into the bios and switch it to Legacy instead of UEFI and then reinstall Ubuntu. Then it worked fine.

See more evidence of this: http://askubuntu.com/questions/141879/error-1962-no-opertati...

http://askubuntu.com/questions/91484/how-to-boot-ubuntu-from...

brfox··on Disney to Acquire Lucasfilm Ltd.
I agree. After we visited Disneyland this year with my kids, I looked up the profit to Disney from movies vs theme parks, and they make a lot more profit on theme parks than movies. So, you could consider that the media arm is just an advertisement to get people to visit Disneyland/World parks.
brfox··on Apple's New Pinch-To-Zoom Monopoly is Bad News
Those are probably patented, also.
brfox··on Healthy Labs (YC S12) Wants To Be Go-To Site For People With Chronic Illness
Looks nice! I've been thinking about a project like yours and bought peerhealth.com several years ago with the hope of doing something like you have done. For other companies (which I'm sure you're familiar with), see also http://patientslikeme.com and http://curetogether.com (just bought by 23andme).
brfox··on Harvard cracks DNA storage, crams 700 terabytes of data into a single gram
Nice work, and thanks for replying to all the questions here. I didn't read the paper, maybe it is addressed in there, but how much did it cost to synthesize that much DNA? Also, it could be random access if you PCR amplified the fragments you need based on the barcodes - you could even make a FAT (file allocation TUBE) which has all the file names and their barcodes.
brfox··on The busy trap
I gave up about halfway - it was too preachy.
brfox··on The busy trap
I am very busy and I like being busy; life is short and there is way too much cool stuff to do. But, at the same time, I try to not use it as an excuse, and I get a little annoyed when people use it that way.
brfox··on Long Exposure Photographs Shot from Orbit
Is that why all the pictures have this faint dark line at even intervals perpendicular to all the city light lines? For example: http://www.flickr.com/photos/nasa_jsc_photo/7216880452/in/se...
brfox··on Ask HN: How to overcome strong feelings of worthlesness and inadequacy
Don't undervalue the benefits of some short-term usage of medication to get back on your feet! I'm a little surprised that no one in these replies has suggested it, but please do consider it - it is a very smart solution! You'll feel better and might make some progress on your goals and then feel better about yourself again. And, heck, even if it is long-term, that's fine, too, don't let these folks be a judge of that for you.
brfox··on Google Just Snuck Most of Chrome OS Onto the iPad
I wish this was available on the Kindle Fire. One of the worst things about my new Fire is that it doesn't have any native Google apps on it... so it is particularly ironic that an Android based tablet has worse integration with Google apps (like contacts and gmail and G+) than the Apple tablet!
brfox··on Show HN: My minimum viable side project
Here's a website I made a few years ago: http://www.babynameclusters.com/name/Tristan/Male

That's a good guess regarding the Brad Pitt character. I should add movie character names - those might be more influential than famous people in wikipedia.

brfox··on Kurzweil's rebuttal to Paul Allen
I don't think energy production needs to change very much. One dimension of computing improvement over the past N years is that cpus are getting faster per unit of energy. So, it takes less and less energy for more and more powerful computers.

Remember that our brains only need a couple thousand kcals per day.

brfox··on Teenagers Will, Like, Totally Abandon Facebook for Google+
One of my co-workers said that her high school son, and all his friends, use Google Buzz very frequently. I haven't talked to her since Google just announced they were closing it down, but what is your report "from the trenches" of high school regarding Google Buzz? Does anyone use it? Buzz has a lower age requirement I think.
brfox··on UARS satellite: New images of tumbling spacecraft
I can't decide if this is a dumb question or not, but why does something like the ISS always face the surface of the Earth in the same direction? For example:

http://www.youtube.com/watch?feature=player_embedded&v=7...

I know the reason the moon is always facing the same face toward us is because it has locked its own rotational rate to match it orbital rate due to "tidal like" forces acting back on the moon.

So, maybe I just answered my own question, I guess they purposefully added a rotational component to the ISS so that it is always facing the surface as it orbits? Why do that instead of staying fixed according to the stars? Maybe that is too disorienting for the astronauts.

brfox··on Google's Flipboard Competitor: Propeller
Innovation is the commercialization of a good idea. So, the ideas are easy to come by, but combining the good idea and the commercialization is what really makes something innovative.
brfox··on "site:bartpoa.com inurl:.asp?": BART Police was French girl's first hack.
What is the "one page PDF" that was referred to in this article?
brfox··on Little Exercise, Big Effects: Reversing Aging
And animal models of disease (or aging) are much simpler than real life human biology. One big reason being that lab strains of mice (and maybe the rats in this study, too) are inbred and very homogeneous - genetically speaking. So, something which has a big effect in a lab animal might be due to some strange combination of genes that most "outbred" species (like humans) don't ever have.
brfox··on Gene Patent in Cancer Test Upheld by Appeals Panel
This kind of gene patent is not relevant for drug companies who are trying to make therapeutic proteins.

1. if the whole concept of a "gene patent" (as described in this article) were shut down then drug companies will still be fine, since DNA is not the drug, the protein is the drug.

2. On the other hand, if all 25k human genes were patented by many different parties as diagnostic markers (as described in this article), then it wouldn't hurt drug companies either, since that's not where the money really is. And if something turned out to be important for a drug treatment, then at least there is a patent which can be purchased.

3. Actually, if all human genes (and their proteins) were patented to prevent any use by any other parties, then that would be a good thing, because if it turns out that one of them is really useful to treat a disease, then a drug company would be more likely to pursue that as a drug candidate because they could license the patent and protect themselves from generics for a few years to pay off all the R&D costs.

4. if there is a protein or chemical of some sort which is already in the public domain for your intended use and can't be patented - then there is no way to protect your huge investment. This is the worst case scenario for drug companies. Or, if suddenly there was no way to get a patent for a drug based on a naturally occurring chemical of human protein, then that would be bad for business, too.

Also, this whole gene patent thing becomes a little absurd since it now costs only $4000 to sequence the entire human genome. According to this article, Myriad is charging $3000 to sequence 2 different genes (or maybe just to check for a couple common SNPs in those genes?). So, the problem is, what happens when you get your whole genome sequenced? Does the company who does the sequencing need to withhold the BRCA1 and BRCA2 genes from their product that they return to you? What about all the other "thousands" of gene patents? Maybe when you get your genome sequenced then the company which does it just can't interpret the patented parts of the genome? Well, from this article it look like the interpretation of the gene sequence is unpatentable since it is an "abstract mental step." So, maybe everything is fine and all these patents can exist and we can go ahead and get our genomes sequenced without any fear of getting sued by a Myriad of companies.

brfox··on [dead]
flagged, article doesn't load without account
brfox··on The Higgs Boson - A one page explanation
I like that one, too. But then I read the others and they seem to give a totally different picture, like: symmetric pencils falling in space. It is interesting to read how the different physicists visualize and explain this concept.
brfox··on Google Chrome has 20% global market share
This is why Google+ will surely get a huge audience.
brfox··on Poll: Should HN display comment scores?
Then maybe a comment should get a single star if it gets a moderate share (5%) of the total points, or at least 5 pts, whichever is higher. Zero starts would be the default.
brfox··on Free Business Idea: iPad Marketplace
This sounds kind of like pg's Viaweb?

http://en.wikipedia.org/wiki/Viaweb

brfox··on Domain name valuations
I used to be more likely to click a link on Google if the domain name looked more authoritative. So, a lot of those common names with high prices would seem to be valuable for that reason. And, I think Google ranks sites higher if the domain name has the keyword in it.

These days with so much spam, I try to avoid domain names with my search keyword in them.

brfox··on I'm a pregnant hacker. Please review my side project.
Nice job! I agree about the uselessness of baby name wizard. You did a great job making it more interesting. Are you having any luck getting visitors or higher in organic search?
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