1,560 karma · joined October 21, 2021
I hope it's accurate, because it's interesting. On-demand manufacturing lets you beat economies of scale. I have some beloved print-on-demand comics on my shelf that would never be considered for traditional publication.
Apart from that, "different use case, different intended goal" is cause for what I'd call "ordinary levels of scientific uncertainty." A 13-year-old just starting puberty is not so different from an 8-year-old just starting puberty to justify denying a medication to one by law while still prescribing it to the other without concern.
The opponents of transgender healthcare have used the minor uncertainty of prescribing this medication to a group a few years older to argue not for tighter safeguards, but for a legal ban on prescribing it for that purpose. Not letting doctors evaluate the potential risks and benefits for their patients is one thing, but not even wanting a medical trial to begin to gather more data is outrageous. There is absolutely no concern from these same groups about any risk of the medication to cisgender children, which casts doubt that the concerns are raised in good faith.
> A general subjective notion that the evidence "isn't good enough" with no reference to the level of evidence that is typically used to approve other treatments with similar risks and benefits
> The focus on randomized controlled trials as the only acceptable form of evidence, despite (or because of) their expense and length
> Common and easy-to-collect indirect markers of effectiveness (presence of antibodies, lower reported suicidality) are against them, so they insist on using only rare, hard-to-collect direct markers (prevented illnesses, reduction in completed suicide attempts) despite lacking any reason to believe the results will be different
> The insistence on unnecessary, lengthy trials or tests for treatments that are time-sensitive, to the point of overrunning the time when they ought to be administered (RCTs for flu vaccines that would delay them past flu season, vs insisting on a large and arbitrary minimum number of assessments before allowing puberty blockers such that puberty starts before the patient is approved). For the anti-treatment side in both cases, a long enough delay is effectively a victory that doesn't require them to prove any of their points.
So, what can we draw from these tactics? They want to make their opponents waste time and resources on long, difficult trials (the longer the better,) because every day it goes on is a day that treatment is delayed or a "temporary restriction" can continue. Plus, if they need more time, they can always push the arbitrary standard of evidence they demand arbitrarily higher. They can always demand more trials, or more specific and difficult-to-collect data.
But on some level, they know they can't say "THIS is the study that will prove vaccines/HRT are unsafe" because they understand that the results will probably not go in their favor (or, that they'd get caught if they faked it).
It seems like they understand that the evidence is against them, but that stalemate is in their favor.
Makes me wonder how expensive these were to make.
I'm not sure he's bringing it up for that reason. He thinks the label is losing its power because it really is losing power over him, because he's becoming more comfortable with it and beginning to accept it. Keep an eye out for if he starts to call himself a fascist "ironically".