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Toast_

128 karma · joined March 3, 2015

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Toast_··on How to build your own particle detector (2015)
I think you'd have better luck with potassium salt, but trying different things out is the fun part.
Toast_··on How to build your own particle detector (2015)
Adding a radioactive check-source, like a thorium welding rod, may produce some interesting results. ;)
Toast_··on Fractals Made from Shape Languages and Fancy Geometry
Cool project! I bet these would make great styles for deep dream images.
Toast_··on Show HN: WebTorrent CDN with graceful degradation
Really cool.
Toast_··on Show HN: EuroKeks, a stock exchange parody for memes (35.000 orders processed)
This is fantastic.
Toast_··on The Intel Optane SSD DC P4800X (375GB) Review: Testing 3D XPoint Performance
I'm not really sure about hourly plans. When I was configuring my machine (~1-2 years ago) I was able to select hourly or monthly billing (hourly would've been outrageously expensive).
Toast_··on The Intel Optane SSD DC P4800X (375GB) Review: Testing 3D XPoint Performance
>where you just don't have the ability to run hardware (increasingly the case)

Softlayer has 'on demand' bare metal plans. I'm not sure how cost effective it would be compared compared to running your own box, but the simplicity is nice and they had me up and running in under 2 hours (assembled with customizations).

http://www.softlayer.com/bare-metal-servers

Toast_··on Alibaba Cloud Launches Garlic as a Service
>The taste of science and technology
Toast_··on Ask HN: Is Google App Engine a good option for new startups with limited funds?
MS bizspark may be worth looking into if you're short on funds.
Toast_··on Caddy – HTTP/2 Web Server with Automatic HTTPS
Any benchmarks?
Toast_··on Fruit-sorting robot ‘will disrupt the industry’
Efficiency is a beautiful thing.
Toast_··on The HTTP/2 implementation
Is it worth upgrading from SPDY 3.1? Opinions welcome.
Toast_··on The Case for Teaching Ignorance
When did I make that claim? I said that I think what she's promoting is based more off of relativism, and that epistemology is already an established field; hell, it's quite literally the study of knowledge. So smug!
Toast_··on The Case for Teaching Ignorance
Seems more like she's trying to teach a class on relativism, a subject I wholeheartedly hope stays away from science. Additionally, epistemology already exists, and is a well established field of study.
Toast_··on Startups That Launched at YC S15 Demo Day 1
>The garden consists of “smart capsules” that contain seeds, nutrients and soil that’s geared toward the specific plant. (It’s kind of like a Keurig capsule, but for plants.)

REALLY?

Toast_··on Show HN: Flashfed.com – A flash sale aggregator
Thanks! =)
Toast_··on Why Red Means Red in Almost Every Language
Care to make a citation?
Toast_··on I laugh so hard I get tears: Hacker News Onion (Twitter feed)
>Recruiter mistakenly hires real ninja.

>Team finds this totally sweet until ninja commits seppuku when told to use graphical IDE.

Toast_··on Women, Tech Conferences and the Bullshit Surrounding It
Not to be pedantic, but its logically invalid; no fallacy is needed.
Toast_··on An Overview of Curcumin in Neurological Disorders
Here's a simplified version: energy generation in the mitochondria is based on the energy differential between the intermembrane space and the inner mitochondrial membrane (I may have confused those membranes). Most uncouplers act to reduce that differential, thus causing inefficiency in the system, which is lost as heat.

tl;dr uncouplers mess with H+ ions.

Toast_··on Leibniz's Philosophy of Mind (2013)
His writings on monads come to mind, though I may be mistaken.

Did you know he made a mechanical calculator? Here's a pretty cool link from the wolfram blog: http://blog.stephenwolfram.com/2013/05/dropping-in-on-gottfr...

Toast_··on An Overview of Curcumin in Neurological Disorders
>What is a mitochondrial uncoupler...

Examine link #2.

>why would they help with neurological problems?

Good question—perhaps the alteration in ambient energy in the brain prevents certain proteins form forming (amyloid plaques in this case). Honestly, it's hard to tell; it's under active research.

Toast_··on An Overview of Curcumin in Neurological Disorders
Any uncoupler ought to induce mitochondrial biogenesis, as it's a systemic response due to a lack of energy (I may be mistaken?)—same goes for [vascular] endothelial growth factor and EPO (just to name a few).

Also, I really can't recommend reading the paper associated with the third link enough.

Have you tried ephedrine to help with the post-workout swelling? The common 'ECA' stack might be right up your alley.

Toast_··on An Overview of Curcumin in Neurological Disorders
This isn't too surprising considering curcumin is a mitochondrial uncoupler[1][2]. For the curious, another example of a mitochondrial uncoupler would be 2,4-dinitrophenol, which is currently being looked into as a potential anti-Alzheimer treatment[3]. Cool stuff.

1: http://www.ncbi.nlm.nih.gov/pubmed/19715674

2: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567840/

3: http://www.ncbi.nlm.nih.gov/pubmed/16754295

Toast_··on [dead]
Articles like this, and the frustrations expressed, really help to reaffirm my belief that Philosophy, or at least deductive logic, ought to be a necessary part of our public school system.
Toast_··on Ask HN: Just curious, how prevalent is the use of nootropics‎ among HN members?
Damn, where do I sign up?
Toast_··on FBI investigating 11 attacks on San Francisco-area Internet lines
I really wish that didn't sound so plausible...
Toast_··on How Snobbery Helped Take the Spice Out of European Cooking
From what I remember reading, ancient Babylonians really seemed to enjoy garlicy/fatty foods. I'll edit with a citation if I can find a good one.
Toast_··on With 61 Seconds in a Minute, Markets Brace for Trouble
Just to stir further reading, our moon is actually stealing our rotational momentum (our spin speed). Enjoy the rabbit-hole. 😀
Toast_··on A 17-year-old invented an ingenious way to instantly stop bleeding
Quikclot?
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