roscoebeezie

I haven’t had a chance to look through some of the new predictions, but I know there were some issues with predicting the structure for membrane bound proteins previously. PDB hardly contains any.

Does the new set of predictions contain a bunch of membrane bound protiens?

I reading the article I think the ships from The Expanse were aptly named

Sounds almost like the Protomolecule from The Expanse series.

It’s entirely possible I don’t understand how technology works, but I don’t understand how some sort of government encryption backdoor of various protocols would work.

Software, devices, protocols etc are not just used in a single country. They are used worldwide. If a backdoor needs to be supported for a several dozen governments, each with various levels of security practices, there’s no way it stays secret for long. It’s only a matter of time before a country or state like Georgia gets it’s old poorly configured IT infrastructure hacked and the attackers now have access to some backdoor keys. How do governments revoke old keys and create new ones across all applicable devices? It’d be pretty hard to do that without going to companies and saying “fix” or “get me that” with some type of warrant or court order. That is kinda like what we have now which is mostly limited user information located in the cloud somewhere.

I think the larger issue is that there is a coordinated push to get complete government access to everything. This is happening at a time where dystopian surveillance is not only quickly becoming possible, but also profitable. The government has the right to pretty much everything legally, but the potential for misuse in situations where the government gets access everything is really high. The ability for citizens to combat that misuse is reduced the more government gets.

This is my understanding of things. Let me know how I’m wrong.

Maybe excess energy could be used to recycle limited and precious elements from landfills via Santa Claus machine-like disassembly with very hot plasma. Horribly energy inefficient but may be useful in some situations.

Disclaimer: I’m not a scientist, but I want to be.

For things like cancer cells which from a cell surface perspective, can look a lot like healthy cells, I don’t know how one only modifies DNA/RNA expression in only cancer cells. It would have to be all cells with maybe some cellular diagnosis logic in the DNA/RNA itself. Even then cancer evolves. It would have to done multiple times with something like cell descendents information.

I think the author is just another oh so popular mainframe evangelist as he's stated. He could have easily made the same case for any properly managed distributed system.

Where I disagree with him is that I don't think right out of college professionals should be working in a mainframe environment. As a person who has spent the past 3.5 years (right out of college) working in mainframe capacity planning and performance, I think mainframe technology can be pretty niche and I very nervously wonder if my very specific mainframe systems engineering experience will translate anywhere else. I feel as though getting a new tech professional started in their career would be better in an environment that is popular and they are familiar with, and then working from there.

Location: Atlanta, GA

Remote: No

Willing to relocate: Yes

Technologies: Python(Pandas,Numpy, etc)/SAS/R/Mainframe/VBA

Resume: Email if needed

Email: roscoe1245@gmail.com

I'm a Systems Engineer Currently doing work in Mainframe Performance and capacity planning. I've got a background in analysis/math, but I'm looking for more of a Data Engineer or software development role. I'd be open to other possibilities as well.

I'm not OP, but what about the realm outside of rational protien design? DNA base paring rules are pretty well understood and we should be able to build useful tools using them. Is there any work out there using only for computation?

I’ve noticed CNN has had a crap ton of redirect ads recently...

Realtek.

X230 user here (non-IPS). The touchpad isnt just crap, it’s unusable. I’ve also had issues with non-intel wireless card.

Location: Atlanta, Georgia

Remote: Yes

Willing to relocate: Yes

Technologies: Python, SQL, SAS, R, a bit of JavaScript and Java,Deep Learning.

Resume: via email Email: roscoe1245@gmail.com

I’m a Systems Engineer with a few years doing Capacity Planning and Performance for mostly legacy mainframe systems. I have done a bit of work doing data analytics as well. I’m looking for more of a developer type role. I have an interest in AI, Robotics, and Biology.

One thing that helped me was to draw pictures both before and during proofs.

Yeah as a person who works heavily in the airline ticket pricing world, that’s not how it works.

As a person who doesn’t understand containers, where do I go to learn the basics?

I once had the exact same idea as these guys.

The three: Amedeus, Sabre, Travelport(Galileo, Apollo, Worldspan).

Disclaimer: I work for one of these.

When CMS is not Conversational​ Monitor System...

Yeah a lot of this stuff is on old school mainframes written in assembly. I work in the airline/travel industry and I've seen 28 year old code still running in production.

I don't think an AI has to kill people to be super dangerous. What if a social AI was used by some group to sway/manipulate public opinion on some important issue? How much manipulation would it take to be dangerous?

Queue John Quincy Adams: https://www.mtholyoke.edu/acad/intrel/jqadams.htm

As one who claims to know C on my resume, but I too am a < 3 month novice, lemme try to answer this one.

You declare some pointer and give it whatever value 'c' is?

I probably would have gotten the question wrong too and just saying "Get out" is kind of harsh.

I had thoughts for some bci product. I have no clue about the feasibility.

Take an EEG like the emotiv Epoch. Get lucky and hope you can still get the raw data via emokit or something like that. Construct some sort of low level two character alphabet representation. I'd imagine something similar to EBCDIC cause I'm a tortured mainframe soul, so C1 is A and so on. Using some fancy ML (deep learning?), train for your alphabet representation using EEG data while loudly subvocaling "C" or something.

Once you get lucky and train a model, use your alphabet as some sort of string of consciousness recording/ instant note taking. Some how tag your thought notes so you can come back later or do some fancy searches. Do some fancy NLP on your notes or some conceptual blending or whatever is cool. Sell the software, but keep the notes "open" somehow.

I'd go on but that's my idea. Steal it and hire me.

This is actually the first time I've heard this. Like really.

Lucrative? No, but someone has to maintain the legacy nightmare. Most mainframe developers (i've run into) are very close to retirement age, so companies are trying to hire younger talent and will often put them through paid mainframe programming classes.

But mainframe sucks. Nobody gets into it cause the like it, they just need a job. I'd like to see a startup that sells mainframe software, cause they'd be be like one of 3 people.

As a 23 year old mainframe programmer who writes COBOL, I couldn't agree with you more.

Location: Atlanta

Remote: sure

Willing to relocate: Maybe

Technologies: Python, R, Java, C/C++

Resume: see email

Email: Roscoe1245[at]gmail[dot]com

Looking to actually do software development. Currently I work with mainframes more as an analyst. Hire me part time or for weekends, I just want to gain more experience writing code.

Location: Atlanta, GA

Remote: Yes

Willing to relocate: Yes

Technologies: Python, Java, R

Résumé: Via email

Email: roscoe1245[at]gmail[dot]com

Graduated in May with a B.S. in math and I'm looking for something data related. Failing this, maybe I could break into IT with a help desk position.

Location: Atlanta, Georgia

Remote: Yes

Willing to relocate: Yes

Technologies: R, Python, SPSS, Linux, Excel, Java

Résumé: send an Email.

Email: roscoe1245[at]gmail[dot]com

I'm a recent graduate with a B.S. in math looking for my first real job. I'm interested in machine learning or data stuff, but all I really want to do is code. I have some experience coding in R, Python, Python, and Java.