Hacker News Reader

qclibre22on Automatic1111 for Apple metal, 40% speed up sd1.5

There's also sdcpp ( https://github.com/leejet/stable-diffusion.cpp ) . It is for people that know command line shells like bash or Powershell. SDCPP is like llama.cpp but it is for using text to image AI models. Not everyone likes the node/graph programming interface in Comfy or a Webpage interface. Some people need these GUI/web interfaces and get lost and frustrated in shell scripting.

qclibre22on S&P 500, Nasdaq drop as tariffs spark recession fears

https://finance.yahoo.com/quote/%5EGSPC/

S&P is actually up as of time of the posting of this story on "HN new".

qclibre22on Ozempic increases risk of debilitating eye condition: studies

Appears to be two science research papers:

Paper: https://www.sdu.dk/-/media/files/om_sdu/fakulteterne/sundhed... "Once-weekly semaglutide doubles the five-year risk of nonarteritic anterior ischemic optic2 neuropathy in a Danish cohort of 424,152 persons with type 2 diabetes."

Preprint : https://www.medrxiv.org/content/10.1101/2024.12.09.24318574v... "Use of semaglutide and risk of non-arteritic anterior ischemic optic neuropathy: A Danish–Norwegian cohort study"

qclibre22on AI model for near-instant image creation on consumer-grade hardware

git clone https://github.com/lllyasviel/stable-diffusion-webui-forge.g...

download models and all vae files for the model, put in right place, run batch file, configure correctly and then gen images using browser.

qclibre22on Limbo: A complete rewrite of SQLite in Rust

Why not do both? Release as public domain or MIT license. Take your pick.

qclibre22on HuggingFace Is Down

Appears to be okay now. Your status page is okay and a playground image gen service ( https://huggingface.co/spaces/black-forest-labs/FLUX.1-schne... ) works.

qclibre22on Midjourney web experience is now open to everyone

So google will rank them higher in search results?

qclibre22on Ask HN: Help with Glioblastoma

Glioblastoma is very bad news. CAR-T cells are promising but very new and experimental.

Start here: https://duckduckgo.com/?t=ftsa&q=car-t+cells+for+glioblastom...

Getting into a clinical trial will be difficult.

qclibre22on Schwab users are unable to log in

https://finance.yahoo.com/quote/HOOD/

Robinhood down 15% this morning.

qclibre22on Japan stocks plunge as much as 7% as Asia shares extend sell-off

S&P futures are down 1.4% at 10:57pm EDT. Markets open at 9:30am EDT.

qclibre22on Proteins in blood could provide early cancer warning 'by more than seven years'

You can be denied some kinds of health insurance : https://www.medicarefaq.com/faqs/can-you-be-denied-a-medicar...

qclibre22on Most of Europe is glowing pink under the aurora

Typo, that's NOAA, not NASA.

qclibre22on Google lays off hundreds of ‘core’ employees

https://www.jstor.org/stable/3088174 : "Results show that layoff announcements trigger negative returns for both U.S. and Japanese firms. Specifically, layoff announcements of U.S. firms are associated with a negative 1.78 percent abnormal return ..."

https://onlinelibrary.wiley.com/doi/10.1111/1748-8583.12532 : "They find that investors do not react if a layoff announcement signals proactive management (e.g., cost cutting) but penalize the firm if the layoff indicates reactive management (e.g., decline in demand). The penalty is also positively associated with layoff size but unrelated to firm size. Further, investors have become less punitive over time, or if its stock is traded on an exchange in civil law (vs. common law) country. "

qclibre22on Complexity Is the Enemy (2011)

How about : "write your code so that someone else can easily port it to another language" ?

qclibre22on Turchin's Terrifying Predictions

Employed full time: Median usual weekly real earnings: Wage and salary workers: 16 years and over : https://fred.stlouisfed.org/series/LES1252881600Q

qclibre22on Breakthrough drug trial saw cancer vanish in every patient (2022)

2023 news: original paper : https://www.nejm.org/doi/pdf/10.1056/NEJMoa2201445

qclibre22on A love letter to Apache Echarts

vis.js is great for it's simplicity of interfacing with and just works.

qclibre22on There's a Reason McDonald's Coke Tastes Better Than All Others

A few bars in America do coke with ice exceptionally well. Not sure what the trick is but it's always from that multibutton nozzle liquid delivery device.

qclibre22on A woman who can smell Parkinson's is inspiring research into diagnosis (2020)

On a ketogenic[diet] ... your body uses fat instead of carbohydrates for energy. This shift causes a major spike in ketones, the source of acetone breath. ... Sweet-smelling breath may be a short-term side effect of this type of diet.[0]

[0] https://www.webmd.com/diabetes/acetone-breath-diabetes

So low blood sugar causes sweet breath.

qclibre22on AMD Athlon K7 Easter egg has a revolver and map of Texas etched onto the chip

Fastest gun in the west?

qclibre22on FTC investigating Adobe over making it too hard to cancel subscriptions

I think Congress should pass a law that if you send a registered letter to the legal department of these e-commerce companies with your name, address and credit card number with an order to drop the service then they have to process it and cancel your "subscription". Companies would be required to print out the address of their legal department on the ordering page and sign-up page. Right now if you complain to your credit card company they won'thelp you and will refer you to the company which won't help you.

qclibre22on Cardiometabolic Effects of Omnivorous vs. Vegan Diets in Identical Twins

> ghee Ghee is a type of butter, so not vegan.

qclibre22on Dietary fiber intake and all-cause and cause-specific mortality

"ColonBroom’s ingredients center around improving your gut health through increased fiber intake. Psyllium husk is the main ingredient in ColonBroom. It’s a soluble fiber ...

https://colonbroom.com/ingredients

qclibre22on The Small Website Discoverability Crisis (2021)

Click on user name to see their profile.

qclibre22on CVS ditches common cold meds after FDA advisers say they're useless

I think he might have meant this : "Codeine is a widely used analgesic, that is available for sale in pharmacies over the counter (OTC) in a number of countries including the UK, South Africa, Ireland, France and Australia." [0]

[0] https://www.drugsandalcohol.ie/25048/#:~:text=Codeine%20is%2....

qclibre22on BioNTech presents positive phase 1/2 data for CAR-T cell therapy candidate

> you can’t remove CAR T cells

Well there working on blood purification in severe cases: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245117/

"Four-day extracorporeal blood purification resulted in complete resolution of immune effector cell-associated neurotoxicity syndrome and greater than 95% reduction in interleukin-6 levels without side effects"

qclibre22on When XML in Word Became Illegal

> Scientists will thank you

Scientists gave up and changed the gene names: https://duckduckgo.com/?q=excel+gene+names+changed+septin1

qclibre22on When does federal debt reach unsustainable levels?

> If the US was an IMF country

The U.S. is in the IMF and has used it to borrow.

qclibre22on Kevin McCarthy ousted as speaker in Republican-led House

Electoral college is not first past the post.

qclibre22on Gene linked to long Covid found in analysis of thousands of patients

You're probably right. Look at figure 3 in the paper. The effect is for region upstream of FOXP4. The reported Prometheus snp ( rs1983891 ) is not in this region, it is in an intron in FOXP4.