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pombrand

54 karma · joined April 24, 2014

Norwegian molecular biologist working on skincare.
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pombrand··on Hawaii moves to ban sale of sunscreens with coral-harming chemicals
..and as the first paper says, ZnO nanoparticles are NOT toxic if silica coated, so devil is in the details here. It should also be noted that no in vivo toxicity has been demonstrated from non-coated nanoparticles, although there's a theoretical potential for it.

In the second study ZnO nanoparticles were injected DIRECTLY INTO THE BLOOD of rats with no control for non-nano particles. Crazy they even got it published.

pombrand··on I switched from iPhone to the Pixel 2: One-week report
Android has system wide ad blocking not requiring root through the DNS66 app, this alone makes me prefer Android.
pombrand··on Microplastics found in 93% of bottled water tested in global study
I worked in a lab and where we used an atomic force microscope to scan single DNA strands on flat surfaces. At first we couldn't "read" anything as the surface was covered in gunk from the water we used, switching to water in glass bottles fixed this.
pombrand··on A startup is pitching a mind-uploading service that is “100 percent fatal”
It's a bit pretentious to think that any being would bother to spend precious free energy to torture a bunch of lowly humans don't you think. Hence not worried.
pombrand··on Facebook lost around 2.8M U.S. users under 25 last year
Exactly right. I've gotten around this by using "Facebook Purity" a chrome extension which let's me filter what is shown on the news feed in detail: I only really want to see posts and photos the friends I haven't hidden from the news feed post - not their likes, the events they're going to etc. This is addition to "hide trending" and ublock makes facebook a bit broken but overall usable, not really worth checking in more than once a week though.

Instagram works better for getting a feel for your friends, especially with the temporary "snaps" people post and actually fun creative overlays.

pombrand··on After Surgery in Germany, I Wanted Vicodin, Not Herbal Tea
Yet moderate Ibuprofen use is harmless to the liver - so much for German rationality: https://livertox.nlm.nih.gov/Ibuprofen.htm, that said you could look at a ~20% reduction of Serum testosterone over time http://www.pnas.org/content/115/4/E715
pombrand··on The Netherlands has become an agricultural giant
From going through this whole thread. Best bet Tomato rankings are as follows:

1. Homegrown (in good soil) 2. Italian 3. Albanian (heirloom) 4. Spanish

Smaller, darker and more aromatic are generally better (cherry a good bet), and they're all best in the summer. Did I forget anything?

pombrand··on Ask HN: Books you wish you had read earlier?
"Peak: Secrets from the New Science of Expertise" because I've been learning ineffectively my whole life not knowing that I was. Should be required reading for every 15 year old. The best, most science based book I've ever read about learning effectively.
pombrand··on Juice may taste good, but unlike the fruit, it’s not healthy
The realnews headline: "Juice in excess is not healthy. Same goes for fruit." Guess that wouldn't get many clicks.

As long as you don't consume too many calories or spike your insulin too high by drinking large quantities at once, juice can be healthy. The phytonutrients and vit c will prevent the uric acid serum spike you get from fructose, soft drinks have also been proven not to increase c reactive protein. Although with less fiber it'll always be inferior to eating (or drinking) whole fruits.

pombrand··on Replacing butter with vegetable oils does not cut heart disease risk (2016)
What you really need is a study comparing saturated fats, ideally from butter AND from coconut oil, with monounsaturated fat which is the plant fat recommended as healthiest (olive oil, avocados, almonds), not polyunsaturates that no-one claimed was particularly healthy to begin with. It also needs to looks at all cardiac events, not just death (having cardiac events can reduce life quality).

If you read the wiki about saturated fats https://en.wikipedia.org/wiki/Saturated_fat_and_cardiovascul... it's clear that there's no benefit from saturated fats, but potential downfalls.

A more useful headline: "Replacing butter with vegetable oils high in monounsaturated fatty acid reduces risk of cardiac events and neurological disorders" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705810

So much butter confirmation bias here.

pombrand··on Lenovo ThinkPad T460 – A Good Linux Laptop for Development
You can replace the T420 screen with a $45 Alienware 1600x900 screen that is allegedly plug-n-play and amazing https://www.reddit.com/r/thinkpad/comments/4no5ak/t420_alien...

Considering doing it to my T420S :)

pombrand··on US government to withdraw longstanding warnings about cholesterol (2015)
For those of you who still believe it's OK or even good to eat a lot of saturated fats, if you look at the studies it's not much of a controversy:" Whether saturated fat is a risk factor for cardiovascular disease (CVD) is a question with numerous controversial views.[1] Although most in the mainstream heart-health, government, and medical communities hold that saturated fat is a risk factor for CVD, some hold contrary beliefs." https://en.wikipedia.org/wiki/Saturated_fat_and_cardiovascul...

Anecdotally, I've read 50% of people who go on Keto see a huge 2-3x increase in triglycerides and LDL-P (Particle count as measured by NMR) - the #1 risk factor for cardiovascular disease. More LDL particles bouncing around in your arteries = bad. People with a condition that makes them break down more LDL have much less artheroscleriosis: http://www.nejm.org/doi/pdf/10.1056/NEJMoa054013 People with a condition that makes them have more LDL particles get more artheroscleriosis: https://en.wikipedia.org/wiki/Familial_hypercholesterolemia Read Peter Attila's exposition that goes in detail (eating cholesterol is fine though): http://eatingacademy.com/nutrition/the-straight-dope-on-chol... Keto could work, but it's a hyper-pro level high-risk diet requiring frequent blood work and still avoiding saturated fats keeping them primarily monounsaturated which makes it very hard to follow. Plus it sucks for weightlifting..

Surprisingly, very low fat diets might be great for you, it might not be the absolute macronutrient composition that matters, but rather the specifics of the nutrients (GI, fiber, other nutrients etc) and your genetic makeup: https://deniseminger.com/2015/10/06/in-defense-of-low-fat-a-... Scary correlations about saturated fats and neurodegenerative disease therein too.

Personally I'm sticking with a "balanced" ~10/45/45 carbs from protein, low GI carb/monounsaturated fat vegan diet - not wanting to risk side effects of any extreme (although I'm having to ensure adequate calcium, K2, D, B12 and DHA and EPA intake - If I didn't find it unethical to eat fish a pescetarian variety would likely be easier/healthier/less gassy). Tip for you vegetarians/vegans: look up low FODMAP foods; foodstuffs low in carbs indigestible in the small intestine which tend to produce more gas.

pombrand··on Bloody Plant Burger Smells, Tastes and Sizzles Like Meat
Huge problem with the vegan meat replacements is that they're a lot more expensive than beef, around $7/lb vs ground beef at $3/lb. Like with coal vs solar, for imitation meat to win the market it needs to get less expensive than real meat (and taste as good).
pombrand··on Why Stanislaw Lem’s futurism deserves attention
I'd also note that to predict someone's future behavior, you'd have to predict everything in their future environment, and I'd assume simulating a large part of reality would cost a lot of energy - and if we're facing heath death, energy is all we, and the minds, have got. So economically it would be a minor form of suicide.
pombrand··on Stanford study finds walking improves creativity (2014)
We need a follow up study comparing the effect size to that of showering..
pombrand··on Hidden tricks of persuasion: study shows how easily we are manipulated
In what case(s) did you get a 200% increase in conversion, and what's your explanation of that effect?
pombrand··on Hidden tricks of persuasion: study shows how easily we are manipulated
I wrote a summary of Cialdini's legendary book "Influence" if any of you are interested in reading more about this topic: https://medium.com/@johanaardal/a-summary-of-influence-d443a...

I feel that a lot of these effects are more effects of nudging a customer to take action rather than making a customer buy something they normally wouldn't. Increasing conversion rates from a typical 2% to 2.2% isn't that huge.

I'm more interested in the outliers, in what cases do you get a 200% effect? And in what cases can these tricks influence important decisions? What house you buy? What medical insurance to get? Thoughts?

pombrand··on The Itch Nobody Can Scratch
Keep in mind that it can be flea bites, as they only start to itch after several hours, you'd usually feel it when you wake up in the morning (and suspect it was bed bugs). A great way to test for this is to get a flea bite trap from amazon.

Def something to look into this if you have animals.

pombrand··on Lecture 9: How to Raise Money
Wrote a quick summary of key points in the talk - it really shows what the "top VCs" are looking for, go big or go home: https://www.facebook.com/johan.aardal/posts/1015274252107585...
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