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nobodyknowsyoda

108 karma · joined January 29, 2021

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nobodyknowsyoda··on Launch HN: Heimdal (YC S21) – Carbon neutral cement
What is the current price of carbon credits in the ETS? I am from the USA / am dumb, so don’t know how to find it

Also good read for everyone: https://www.gatesnotes.com/Energy/Introducing-the-Green-Prem...

nobodyknowsyoda··on I created a $350M software company knowing nothing about software (2015)
Yeah that was hilarious. Also:

> Many of my friends who are founders of their own companies tell me how they exhibited the entrepreneurial spirit as a kid… But that wasn’t me.

Literally next sentence:

> I ran a small gambling operation

nobodyknowsyoda··on The Future of Ocean Farming
Wow, thank you for this!! This is really fascinating.

Do you have a better link to the project specifically and/or the engineering system? I could not find any photos. The only thing I could find was this https://www.climatefoundation.org/uploads/3/0/2/0/30209783/m...

nobodyknowsyoda··on RNA demethylation increases rice and potato yields 50%
Oops, thanks
nobodyknowsyoda··on RNA demethylation increases rice and potato yields 50%
Unfortunately don’t have time to check out the paper, but vaguely I am aware that methyl groups are like an accessory that can be attached or detached (by the cell, normally) to an arbitrary section of DNA within your chromosome. And it can be used in this way for regulation of DNA expression. Because when the methyl group is there it’s harder for that section of DNA to be read (transcribed) because the methyl group is physically in the way. The train can’t run on the track because there’s a big rock on it

DNA is like code, but then there’s this whole meta level of DNA regulation that determines whether each section of code is used, and how much

So by demethylizing some section of the DNA, implicitly that means the scientists made that section of DNA be used more often. And it just so happens that when that section of DNA is used more often it contributes to various processes that ultimately end up with the plant organism as a whole producing more “yield”, or parts of the plant that we like to eat

https://en.m.wikipedia.org/wiki/DNA_methylation

nobodyknowsyoda··on Restaurant workers quit at record rate
Oh dear, I hate to jump in but “whom” is the correct usage here. Grandparent is echoing great-great-grandparent, and since one pays her, one pays whom

> if you can replace it with “him” or “her,” use whom

Source: parent

nobodyknowsyoda··on CRISPR gene-editing breakthrough opens door to treating broad array of diseases
> They’re called “plants.”

Incidentally, CRISPR + plants is one of the most promising solutions to climate change: https://www.ted.com/talks/joanne_chory_how_supercharged_plan...

nobodyknowsyoda··on MPs: Octopuses feel pain and need legal protection
There exist dumb rich people who drink unpasteurized milk, and then get diarrhea or worse. It seems unimaginative of you to suppose that meat that comes from a live animal will always be necessarily higher quality than meat that comes from cultured cells. I, for one, would prefer a lab grown meat over a farmed meat whose tissues are infused with antibiotics and is generally covered with feces emitted from the slaughtering process
nobodyknowsyoda··on MPs: Octopuses feel pain and need legal protection
Obviously not great, therefore doing less of it holistically is useful. You do realize most of that soy goes to feeding livestock...
nobodyknowsyoda··on In 1850, Ignaz Semmelweis saved lives with three words: wash your hands (2015)
Probably not good for individuals. I am a germophobe and my immune system is a lot weaker than my friends who share drinks, eat stuff off the floor, eat street food, kiss random strangers etc[0]

Probably great for the population and likely to increase Earth’s carrying capacity of humans, as is the case with most technological progress (hand washing, plumbing, agricultural techniques increasing food production per hectare, micronutrient fortification). We become dependent on these things and as long as they stick around as reliable infrastructure then we are good

It is important to keep in mind, however, that exposing oneself to pathogens from other humans is distinct from exposing oneself to various neutral microorganisms from the environment that help diversify your micro biome and generally make your immune system stronger. “What doesn’t kill you makes you stronger” does not apply to oneself and Ebola or HIV or even malaria in a very practical sense. Perhaps most relatable to Hacker News folks is that each infection in one’s body offers a nonzero chance of lowering one’s IQ. That should suffice as reason to avoid disease

Edit: [0] I get sick a lot more easily than they do, and uh, it took me 9 months to recover from Covid (long Covid)

nobodyknowsyoda··on Apple admits it ranked its Files app ahead of competitor Dropbox
Slightly off topic, but I do love the translucent terminal on the Mac. It is very cool
nobodyknowsyoda··on Fewer young men are in the labor force, more are living at home
> But again, what should we do with very strong, very stupid men? There used to be an abundance of jobs for them, some of which paid well. Nowadays there are no jobs for them.

Last summer I took a job in construction. Construction fits the bill of what you’re describing. There needs to be more construction in America

nobodyknowsyoda··on The WHO-China search for the origins of the coronavirus
You do realize the rise in attacks on Asian Americans are not simply anecdotes from the media but shows up in the statistics and police reports?
nobodyknowsyoda··on The days are long but the decades are short (2015)
37) If you find something “Open”, make sure to Close it

/s

nobodyknowsyoda··on Big name corporations more likely to commit fraud: study
"We compiled data on 250+ US public companies involved in corporate securities frauds identified in 1,000+ Securities and Exchange Commission filings over 2005–2013; we randomly selected a comparable control group of 500+ US public companies from Compustat."
nobodyknowsyoda··on Some Proteins Change Their Folds to Perform Different Jobs
I’m probably preaching to the choir, but yup that inherent uncertainty seems to distinguish biology from the other sciences. There is a huge stochasticity & serendipity in everything because there is no intentionality in the design of any biological component; any convergence toward a chemically or physically optimized component or behavior is driven by evolution by natural selection but remains imperfect. Warts, quirks, and all

It also explains how the folks on HN positing “Covid is just the flu” and “long Covid isn’t real” have been so confident yet so gravely mistaken. They are used to other sciences where there is much less room for uncertainty

nobodyknowsyoda··on Open Source Mission Control Software from NASA
They use this at The Boring Company