In UK there was just recently published Guidelines for [1] Safe prescribing of fluoroquinolones.
'Do not use fluoroquinolones in patients with known aortic aneurysm, aortic dissection or history of serious side effects related to quinolone treatment (including tendon disease/disorder) unless there are no other treatment options available'
'Patients should be counselled to discontinue fluoroquinolone treatment and seek urgent medical attention at the first sign of:
- Tendon pain or inflammation (particularly in shoulder or ankle)
- Symptoms of neuropathy such as pain, burning, pins & needles, tingling, numbness or weakness
- Sudden-onset of severe and constant abdominal, chest or back pain
1. https://www.ncl-mon.nhs.uk/wp-content/uploads/Guidelines/5_F...