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justinko

58 karma · joined January 4, 2012

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justinko··on Looming demise of the 10x developer – an era of enthusiast programmers is ending
No, “treatment” is going to consist of stimulant medication, which long-term, will decrease quality of life.
justinko··on An open-source alternative to QuickBooks
Hmmm this smells like a biz opportunity
justinko··on HBO Max new Captcha system
Well that’s one way to get to front page of HN …
justinko··on Ask HN: How to restore cognition after years of trauma? I feel slow and dumb
Besides the obvious remedies, do a couple high dose rounds of Cerebrolysin.
justinko··on Ask HN: I’m Lost. Help?
Do nothing. Binge tv shows. Go on long walks. Hit the gym. Your mind will pull passion out of boredom and restlessness. Lean into it.
justinko··on Phony diagnoses hide high rates of drugging at nursing homes
Yes. Also, the name "antipsychotics" is of no help either.

The second generation "atypical antipsychotics" are really not much different from antidepressants. They just typically contain an additional dopaminergic effect (e.g. modulation). As someone else pointed out in this thread, Abilify is prescribed for depression and anxiety.

justinko··on Phony diagnoses hide high rates of drugging at nursing homes
I’m on Abilify and Vraylar. Makes me feel normal. Love it.
justinko··on Some Days I Can’t Do Life – When everyday life becomes a struggle (2020)
What substances a bipolar person can consume will vary by the individual. Some can use alcohol moderately, others must completely abstain.

Bipolar is a progressive illness. I have taken psychedelics a handful of times and experienced the purported benefits that last a lifetime. Other times I have experienced extreme paranoia. I guess it depends on what state I’m in (mania, depression, mixed, stable).

I used amphetamines and THC for many years to self medicate before being diagnosed. Self medication is extremely common for bipolar folks, especially alcohol. It only makes things worse.

I’m still figuring out what I can and cannot consume, along with dosage. Since being on a mood stabilizer, I absolutely cannot consume any amount of THC, as it will induce mania. Alcohol will make me incredibly depressed the next day. Medication is new to me this year.

justinko··on Some Days I Can’t Do Life – When everyday life becomes a struggle (2020)
Antidepressants are just fine after you have tried everything to resolve the depression naturally. Diet, exercise, relationships, career, etc. Most often this will work.

Eventually you may need a heavier hammer. Antidepressants can do the job but they are not meant to be used for long term use. The reason is side effects, long term withdrawal/dependency, and the eventual “poop out”. One year should be the cut off.

Fluoxetine, for example, induces neurogenesis. This is the method of action that cures depression. Exercise can do the same thing, which is why you’ll see studies of “cardio is just as effective as antidepressants”. Psilocybin as well.

Chronic stress will reduce your neurogenesis. There are many, many ways in this modern world to experience it.

The stigma of antidepressants needs to end. They can be very useful tools under the right circumstances.

Another thing you have to watch out for is mental illness, such as bipolar, that is not treatable with antidepressants (they can induce mania) nor any holistic method. Mood stabilizers and possibly an “antipsychotic” will be required. I’m bipolar and Lamotrigine has improved my world that no lifestyle change ever could. It’s been nothing short of a miracle drug for me.

justinko··on Take a look at Nomad before jumping on Kubernetes
Or ECS for that matter.
justinko··on Finland has slashed homelessness; the rest of Europe is failing
Recently, here in Denver, I could not find a psychiatrist that accepted insurance. And the minimum out-of-pocket hourly fee I came across was $250/hour. One was $450.

The psyches that did accept insurance had wait times with March being the soonest.

A stark, stark contrast to seeing a cardiologist, for example. The shortage of mental health professionals is real.

Why do we not take mental health more seriously?

justinko··on Testosterone levels show steady decrease among young US men
I feel pretty incredible on TRT.

I’m 36, and started summer of last year with levels in the low 500’s. I’ve done a ton of research to get properly dialed-in.

It’s nice knowing that I’m now shielded from these external causes of low T.

justinko··on Testosterone levels show steady decrease among young US men
Increases protein synthesis.

My blood pressure is incredible now post TRT.

justinko··on New MacBook Pro models to feature magsafe, no touch bar and more ports: analyst
What a taint to his legacy. Not a good way to go out.
justinko··on I almost quit caffeine in one year
It is not. It is absolutely not neurotoxic nor have any other measurable physical detriments.
justinko··on I almost quit caffeine in one year
Yep. 23andMe states I am “less likely to consume caffeine”, which correlates with my caffeine sensitivity.

I still consume it though.

justinko··on Apple M1 vs. Ryzen 3900X vs. Intel I9 in Software Development
Same!
justinko··on I Hacked into Facebook's Legal Department Admin Panel
And the idea of a “hacker agent” was born.
justinko··on Why do most top performers have the highest count of commits and pull requests?
I batch it based on what could possibly make sense to revert.
justinko··on Stimulus.js 2.0
I believe even Basecamp (or one of their products) uses React on a more complex interaction.
justinko··on Sleep duration is associated with brain structure and cognitive performance
14 months of PAP therapy for me. I was diagnosed with severe SA (40+ events per minute).

Sp02 is useful, but mainly to ensure you're not dipping in o2 from leaks, bad fit, incorrect pressure, etc. It is not a diagnostic tool.

A sleep study can pick up things like restless leg syndrome, central vs obstructive sleep apneas, RERA's, etc.

Regarding the "brain fog" - I know exactly what you're talking about. I've improved mine significantly via:

- Getting extensive blood tests to find any deficiencies. Turns out, I was deficient in vitamin D (really bad) and testosterone (which is produced during high quality REM stage, I believe). - Taking a boat load of supplements. L-Tyrosine, NAC, too many to list.

Sometimes PAP therapy doesn't fix endocrine issues like testosterone. Going on TRT has been a game changer for both mental and physical improvement.

justinko··on Sleep duration is associated with brain structure and cognitive performance
Up to 30% of people may have sleep apnea. I recommend everyone to get at least an at-home sleep test. In-lab is much more difficult to get insurance to cover, but you could pay $1,500+ out-of-pocket.

It is a horrendous condition that will ruin your life.

justinko··on Sleep duration is associated with brain structure and cognitive performance
Do you feel basically fantastic every day?
justinko··on Adults with ADHD show decreased function in brain dopamine reward pathway (2010)
Perhaps school and college were the problems and not your ADHD?
justinko··on Adults with ADHD show decreased function in brain dopamine reward pathway (2010)
I’ve read a lot of comments around amphetamines. This is probably my favorite.

Amps turn you into a drone. Any perceived benefit is met with equal or greater detriment.

justinko··on Ask HN: What are the best unknown books you have read?
Sex at Dawn and Civilized to Death by Christopher Ryan
justinko··on Red Flags in Software Developer Job Descriptions
A decade ago it was possible to be a true full-stack developer that kept up with both ecosystems. Much, much more difficult to do nowadays. Hence the explosion of “frontend engineer” positions.
justinko··on Twirp: A new RPC framework for Go
We had to stick to layer 4/TCP via an ELB (as opposed to an ALB).
justinko··on Ask HN: Who is hiring? (November 2015)
LockState | Denver, CO | Programmer | onsite and/or remote

https://careers.stackoverflow.com/jobs/102095/senior-softwar...

Feel free to email me directly at jko@lockstate.com

justinko··on Am I Doing it Wrong?
http://cdn.memegenerator.net/instances/400x/22419205.jpg
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