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ihartley

121 karma · joined April 10, 2008

iain@streamwhat.com

Software Architect in Biotech, Software + Hardware + Biology

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ihartley··on Raspberry Pi: An update for element14/Premier Farnell/Newark customers
This is irritating: I still haven't figured out how to buy one and I "registered my interest" with both of the initial suppliers, neither of whom have contacted me with purchasing info, within hours of the release annoucment.
ihartley··on First intelligence gene discovered
According to the abstract on the Nature Genetics paper, they were looking at this SNP in HMGA2: http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=1078...
ihartley··on Your DNA may carry a ‘memory’ of your living conditions in childhood
We actually have flys in our lab that have been selected for living in low oxygen environments (4% O2 vs ~21% O2 in room air) over the course of 32 generations. While that by itself is not particularly impressive, the really interesting part is that these flies can be put back in room air for several generations, and then re-introduced to the 4% O2 environment and still survive, which wild type flys cannot do.

Here's a link to the paper: http://www.plosone.org/article/info:doi/10.1371/journal.pone...

The relevant info is in the Results and Discussion section.

ihartley··on Your DNA may carry a ‘memory’ of your living conditions in childhood
I'm currently involved in research regarding DNA methylation in mice. Epigenetic modification is really interesting and still not very well understood insofar as how the response occurs. These methylation changes may also occur as a response to other environmental stresses later in life as well as childhood, and other epigenetic modifications may be passed to offspring. We should see some very interesting discoveries that change our current ideas of heritability and response to environmental stimuli in the next few years as we're able to better detect the epigenetic factors in a cost effective manner.
ihartley··on Repairing a dented tuba with magnets
United Nuclear has super magnets: http://unitednuclear.com/index.php?main_page=index&cPath...
ihartley··on Ask HN: Does anyone here drive anything exciting?
In the midst of rebuilding + turbo-charging a '85 BMW 635CSi. Daily driver is a '90 325i Convertible. It's quite fun to drive with the top down and I still get 21mpg with a lead foot.
ihartley··on Skin cells 'turned into neurons' by US scientists
the paper is here: http://www.nature.com/nature/journal/vnfv/ncurrent/full/natu...
ihartley··on Ask HN: What do you drink?
Water (Probably about 1.5 liters a day) Beer (Cases of Stone IPA from costco are nice) Kombucha and Ginger beer that I brew myself Mexican Coke (Sometimes with whiskey) I try to get iced tea at restaurants (with lemonade if they have it)
ihartley··on Ask HN: Good Aeron knock-off/alternative?
I have the Zody chair and I have to say it's pretty fantastic. I was going to buy an Aeron, but even with the size C chair, the lip of the seat dug into my thighs. The Zody on the other hand has an adjustable seat pan so I can move it out so the edge is under my knees.

The adjustable arm rests are also pretty cool and nearly worth the price of admission by themselves. They adjust up/down, forward/backward, left/right and rotate around the vertical axis.

ihartley··on Drowning Doesn't Look Like Drowning
It's amazing that there aren't many tools for drowning response, and any new technology recieves major pushback from the ineffective incumbents in the space. Check out http://life-safer.com/ they make a throwable, bouyant, foam disk that is significantly more effective than anything else available.
ihartley··on Ask HN: Any Headphone Recommendations For Around $100 US?
I have a pair of Grado SR225s that are fantastic, but they're only good when I'm at my desk. For travelling I used to have a pair of Bose QC2s that I got as a gift. Due to the terrible head strap design they broke after 2 years of moderate use. I now have a pair of Audio Technica ANC7Bs that are exactly the same as the Bose, and have a better strap, that I picked up for $140, and they're down to $120 now on Amazon. Apparently the first version of the headphones was so similar to the Bose QCs that they got sued and had to change them slightly.
ihartley··on Addressing The Outmoded Swapping And Paging Strategy in OSX
I have the same drive. I currently have 6GB of VM, but I've had it up as far as 14GB with no issues.
ihartley··on The New Data Center Rack From ... IKEA?
I put a 50" plasma tv on one for a few days before I could get around to getting a better stand. Now it serves as a cheap coffee table and has been loaded to capacity with beer bottles several times. I think they're surprisingly robust for an $8 piece of new furniture.
ihartley··on From Rejection to Acquisition in One Year: One Startup's Story
Demo Day is where all the startups in a round demo what they've been working on. Thus, applying then would be a bit late for that round and a bit early for the next.
ihartley··on In defense of ebook readers
The Kindle DX has rendered all of my PDFs exceptionally well, including graphics. The only issues are that it is only 16 shades of grey-ish and you can't really change the zoom on PDFs (you can rotate the screen to geta little bit of zoom from landscape mode, but that's it)
ihartley··on Why Do Cars Have Fuel Doors on Different Sides?
Most manufacturers put the fuel door on the opposite side from the exhaust pipes. Also, even though it may not seem like a specific side would make any difference in the performance of the car, but when the tank/door are on the opposite side from the driver it keeps the suspension more balanced than if it's on the same side. As such, many performance cars have the gas cap on the right
ihartley··on Ask HN: Where do you live?
I'm in Clairemont right off the 5. It's about 15-20 to Solana Beach from here if you don't go at peak hours. Pretty much everything north of here until Oceanside is fairly expensive, unless you want to go way east. Just try to find somewhere near the freeway as that will save you the most time.
ihartley··on Something's pretty broken with Firebug...
Have you tried opening Firebug in a new window from the window you want to monitor. This will leave the Firebug area closed on the window you're using and the net requests will collect in the Firebug window.
ihartley··on Ask HN: what unwanted domain names are you sitting on?
animedubzone.com

bitsboltsandvolts.com

bitsboltsnvolts.com

bitsboltsvolts.com

cashnik.com

deletetheinternet.com

dunbarsdungeon.com

finihd.com

graphle.net

graphle.org

hotelfreehd.com

maperate.com

phinihd.com

proclamate.com

pussyandguns.com

sandiegomarquee.com

schrodingershotbox.com

sdmarquee.com

seekaview.com

streamwhat.com

ihartley··on Ask HN: Your Hacker Workspace
I had that case on the first computer I built
ihartley··on Poll: What kind of cell phone do you have?
Mine has lived in the same pocket as my keys for well over a year and has no scratches. Do you have unusually sharp keys or something?
ihartley··on The Paradox of Self-Education
I'm about to start doing this very thing. I've got enough money in the bank to last me for quite some time at my current burn rate. I'm planning a 6 month break to start learning guiter and piano, as well as surfing and working on a couple of my startup ideas and I guess I'll see how it goes from there. I haven't had a prolonged period of time where I have had no obligations in years and I'm not sure how long I can sustain such a break.

Anyway, I wish you luck in your own endeavor. It seems rare to find people that really want to have some quality in their life rather than just doing what they think is expected of them by society... well, maybe not here on HN, anyway.

ihartley··on [dead]
Nice use of the Silk icon set.
ihartley··on Tell HN: One URL Per Day
Yeah, of course all of this is opinion. We can't know anything without data, unfortunately. I just think the community would be best served if people had something interesting to say about what they were submitting rather than just trying to submit something that appeals to the general audience here. I think that just has too mcuh potential to lead to gaming the system without giving anything back other than a link.
ihartley··on Tell HN: One URL Per Day
I don't think giving out karma for submitting articles is even the best idea, anyway. The only way you should get karma in my mind is by furthering the discussion of an article. Why should you be rewarded in some fashion just because you found something interesting on the internet? It isn't that hard to do compared to actually discussing it.
ihartley··on Tell HN: One URL Per Day
As to the potentially missed content, perhaps you could submit multiple stories, but they'd go in a queue and only one story from your queue would be pushed public per day.
ihartley··on Laptop of choice for a Programmer, Need Help
I highly recommend the last gen macbooks. I have a second to last gen one and it's a great computer besides the fact that it can only address 3gb of ram. I've recently upgraded to the new unibody macbook which is an amazing machine, but a little beyond your price point of $1000
ihartley··on Users pour forth MacBook trackpad woes
I haven't seen any of the issues people are talking about on the new MacBooks, though I have seen an issue where if I'm resting my thumb on the bottom of the pad like I used to when there was a discrete button I can't do two finger scrolling.
ihartley··on Ask YC: Why is emacs a great editor?
or if you're on a mac you can just use your .emacs file:

(custom-set-variables '(mac-command-modifier (quote control)) '(mac-option-modifier (quote meta)) )

And now your command key is a control and your option key is a meta.

ihartley··on Hackers' Screenshots
http://megadeth.myrok.com/screen.jpg

Obviously rearranged little. Firefox tends to be on the smaller screen opened up to whatever documentation I might need. Terminal lives over there, too. Textmate is fullscreen on the big screen most of the time with various other utilities (CocoaMySQL, Transmit, iTunes) living somewhere behind it.

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