hachiya

In 2005, the below paper was published showing life extension in mice allegedly due to methionine restriction.

So the instant article would make it appear that at least some scientists think they are closer to showing a similar mechanism at work in humans.

From 2005, "Aging Cell" journal:

http://www.ncbi.nlm.nih.gov/pubmed/15924568

Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance.

People interested in caloric restriction, optimal nutrition (CRON), should find the latest research reported on in this article very interesting.

This article reports that a diet low in the amino acid menthionine is hypothesized to be the key to longevity in humans, rather than calorie restriction.

  …in a series of new experiments on fruit flies, scientists
  discovered that simply varying the mix of amino acids in
  the diet affected lifespan.

  *Further study revealed that one particular amino acid,
  methionine, made all the difference.*

  Although flies and people are very different, the
  researchers believe the effects are likely to be conserved 
  throughout a wide range of different species including 
  humans…

  "If it turns it has the same effect on humans, then the 
  message is avoid high levels of methionine."
 

From Wikipedia:

  High levels of methionine can be found in sesame seeds,
  Brazil nuts, fish, meats and some other plant seeds. Most
  fruits and vegetables contain very little of it. Most 
  legumes are also low in methionine.

The Rush University Medical Center researchers also found evidence for a link between alcohol initiating cancer:

    In addition, Forsyth and his colleagues found that the same roster of
    biomarkers was activated in normal intestinal cells treated with alcohol,
    suggesting that alcohol not only worsens the profile of existing cancer cells
    but also may initiate cancer by stimulating the epithelial-to-mesenchymal
    transition.

Interesting comment here from a purported inside source: http://www.engadget.com/2009/10/10/t-mobile-we-probably-lost...

> I've been getting the straight dope from the inside on this. Let me assure

> you, your data IS gone. Currently MS is trying to get the devices to sync the

> data they have back to the service as a form of recovery.

> It's not a server failure. They were upgrading their SAN, and they outsourced

> it to a Hitachi consulting firm. There was room for a backup of the data on

> the SAN, but they didn't do it (some say they started it but didn't wait for

> it to complete). They upgraded the SAN, screwed it up and lost all the data.

> All the apps in the developer store are gone too.

> This is surely the end of Danger. I only hope it's the end of those involved

> who screwed this up and the MS folks who laid off and drove out anyone at

> Danger who knew what they were doing.

Nothing to say here, except that fortunately most people still know the difference between right and wrong and will never accept as normal the disgusting proposals above. I suspect most people deep down do not want such a society full of moral relativism.

No, they simply redefined "marriage" to suit the political climate.

> Being able to marry the one you love is an essential part

> of the freedoms that should be accorded all human beings,

> including those that love others of the same sex as their

> own.

Marriage means what it traditionally means. Redefining it to mean a generic "love" would also mean that kingkongrevenge's example of two elderly sisters could marry, or a mother can marry her son, or a man can marry his horse (provided the horse neighs in consent).

Redefining the word "marriage" to meet the whims of a minority doesn't actually change what a true marriage is.

Besides diet and sleep, a specific possible factor may be a low or deficient level of Vitamin D. If you suspect yours may be low, e.g. from not enough sun, consider getting your 25-hydroxy levels of Vit D checked. Supplementing with around 2000-5000 IU of Vit D a day could boost your immune system significantly if that is a factor.

Avoid Flu Shots, Take Vitamin D Instead by Donald W. Miller, Jr., MD

http://www.lewrockwell.com/miller/miller27.html

Featured Studies: Influenza and Vitamin D

http://www.vitamindcouncil.org/science/research/vitamin-d-an...

H1N1 Flu and Vitamin D

http://www.vitamindcouncil.org/newsletter/h1n1-flu-and-vitam...

> Fun story: I decided to start wearing my hair in liberty

> spikes one time. Every class period that day, each teacher

> started off by asking wtf was wrong with me. I almost got

> sent to the guidance counselor over it.

Shock-value styles don't indicate much to most observers, other than that someone is unhappy with the status quo and wants to shake things up in an immature manner. Seriously, what did you expect to accomplish by that? Do you really think your teacher's response was unjustified? I don't see how such behavior demonstrates a real diversity in anything of importance or value.

> Oh, and there were no ethnic minorites at my school.

So unless the people in your school were BORN different, you are judging them as being the "same", and of diminished worthiness with whom to interact?

Seems almost like racism - prejudging people based on the skin into which they were born.

"and everyone else looking and acting exactly like me."

Is this ever really the case? It seems thrown out there so much, but I've never observed a case of people all acting the same. Especially in a school.

And unlike smoking, driving has practical benefits, i.e. getting from point A to point B, enabling one to have a job, social outings, vacations, etc...

Smoking has no real benefits. It has a short term plus of making one "feel good"; but nobody claims smoking is "good", while the above goals of driving are.

So I don't really know what point you are trying to make. People all know the dangers of driving, but are willing to trade those for the benefits. People know the dangers of smoking, and are willing to trade those because they are addicted, and for no real benefits. There's a big difference.

Brett Slatkin on the difference between PubSubHubBub and rssCloud:

from http://jy.typepad.com/jy/2009/07/pubsubhubbub-rsscloud.html:

In a nut-shell, rssCloud's subscriptions are merely a way of redistributing pings to subscribers. We think this is still on the publishing side of the problem and does not simplify the life of a subscriber. With rssCloud, subscribers must re-fetch the feed to see if it's changed. In contrast, Hubbub delivers the actual changes to the subscriber so they have no more work to do. This makes it much easier to subscribe, and has some nice properties when it comes to scalability.

I've always been impressed by Newsvine.

http://newsvine.com

They fit a lot of content on the page in a well laid out manner that I haven't seen on many sites.

UGC = ?

Hopefully this is a trend that continues in favor of students. Currently paying $100+ for a single textbook that has such a short lifespan (for the original owner, and for others due to the planned obsolence model by textbook publishers) puts quite dent in the wallet for "starving" students.

Renting for a semester makes much more sense.

And don't forget New Hampshire and the free state project.

I found this pretty impressive:

> Then I did the real test. After poking around and finding a tape of my

> old BASIC programs I typed LOAD again and explored the tape. 30 years on

> all the programs loaded from tape just fine and executed. I was able to

> spend a happy few hours playing character-based games that I wrote.

That his programs loaded after 30 years on a cassette tape makes some of those cheap flaky CDs' lifespans look pretty bad.

I agree, a lot of "carpal tunnel" is most likely RSI. This lady explains it in great detail here:

http://www.aboutcts.com/moreon_cts.html

Her main site is http://julstro.com which pertains to the whole body, but the aboutcts.com site deals specifically with carpal tunnel issues.

I'd prefer to not need to be "protected" from a preventable condition in the first place, and fully enjoy the benefits of exercise as well.

Pop science doesn't vindicate textbook science which still discourages high amounts of saturated fat.

And the Massai (and Inuit) referred to in your link are hardly good examples. They have short lifespans (as low as in the 40s), suffer from atherosclerosis and thickening of the arteries. The Inuit are also not long lived and have a high rate of osteoporosis. These groups' "adaptation" to a high protein meat diet is hardly desirable. They are forced to eat a high meat diet out of circumstances, not as a chosen optimal way of life.

http://aje.oxfordjournals.org/cgi/content/abstract/95/1/26

American Journal of Epidemiology Vol. 95, No. 1: 26-37

ATHEROSCLEROSIS IN THE MASAI

I'd suppose I could drink a bottle of pesticide and tell you how I feel, but I would feel rather stupid proving the obvious.

Vague? So high cholesterol, hormones, high saturated fat, and heterocyclic amines are essential nutrients and not toxic to our bodies?

This is a great contribution to the hacker community. I've been using git for about 1 1/2 years, but I can't wait to read this book and learn more.

If you go to the github URL, this is also a great way to see how one can use a markup language like Markdown to write an entire book in the text editor of your choice, e.g. Vim.

Someone from reddit converted the book to PDF and made it available here:

redraftable.com/temp/progit.pdf

They made it appear that the exploit somehow was able to determine that a user-level account with the name of adam existed. SSH shouldn't do this.

Then they made it appear that they were able to log in as adam, and the logs don't make it look like a brute force.

Then they made it appear that somehow privileges were elevated from adam to root, but did not provide any supposed log of how this was done.

Since they are against disclosing vulnerabilities, it seems more likely that these intruders did not gain access through an unknown SSH exploit, but some other way. Once obtaining root, they could paste some proof of being on the system, and simply combine that with the top portion of their log which may be completely fabricated to appear as a 0-day exploit.

Again, if there really is a SSH 0-day, why is an anti-disclosure group revealing one exists?

When reading information on the web or through my feedreader, newsbeuter, I use Zim (http://zim-wiki.org) to take notes on whatever I think I may want to refer back to in the future. I place notes in an appropriate category, apply a datestamp, and optionally add some tags.

Zim automatically indexes everything, so when I need to find out how to apply that cool Rails trick I read about 3 weeks ago, it's easily found.

So, yes, output is very important, and taking notes helps me get a lot more out of my online reading than if I simply tried to make my brain act as a sponge.

I wonder if this also involved switching the Ruby binary to the Ruby Enterprise Edition? Or did you move to Passenger and keep the same Ruby binary?

I agree, Mongrel was a real boon when the alternatives paled in comparison.

The email sent here is informative. http://seclists.org/fulldisclosure/2009/Jul/0095.html

It's informative because it pretends to imply a little information about how imageshack.us was compromised:

  > anti-sec:~/pwn# perl img-scan.pl

  > Found img1.imageshack.us - lighttpd/1.4.18 - SSH-1.99-OpenSSH_4.5

  >

  > [snip]

  >

  > Found img998.imageshack.us - lighttpd/1.4.18 - SSH-1.99-OpenSSH_4.5

  > anti-sec:~/pwn# perl mass-pwn.pl

This would lead one to believe that imageshack was scanned, a system with lighttpd and SSH was found, and it was immediately compromised due to at least one of those two services.

Similar to the copy and paste from the OpenSSH 0-day rumor.

This is information voluntarily provided by the perpetrator, apparently. Since this person is interested in "anti-security" and keeping exploit knowledge secret, why would he let on any information about the compromise, including which service was involved in his gain of unauthorized access?

Why go to the effort to make out lighttpd or SSH were involved, when disclosing this goes against his proclaimed agenda?

Because it likely has nothing to do with the compromise, and these guys enjoy starting rumors and watching the effects spread across the internet?

Hmmm, could be?

This author's previous post was discussed here two days ago at http://news.ycombinator.com/item?id=690656

There seemed to be some controversy with that post, and as I am far from a database expert, but required by my work to know something about them, I am wondering if this subsequent post clarifies or further substantiates the author's points in the first post.

Ah, thank you for the clarification. I apologize for the assumption and not checking further into this.

Great job Nathan and Chris!