Hacker News Reader

erisianon Monica: Open-source personal relationship manager

This project makes me feel sick.

erisianon Lemmy: A Federated Reddit Alternative

I'm not sure this is a huge issue if you set up user expectations adequately. Just like JoeAsshole@gmail.com isn't the same account as JoeAsshole@hotmail.com.

A workable alternative would be using a pubkey fingerprint with an mutable display name, but who wants to help their family sort that out?

erisianon Studies find automatic braking can cut crashes over 40%

It's a bit of a stretch to compare software overriding intentional input from the driver to the introduction of seatbelts.

erisianon Tutankhamun's Meteoric Iron Dagger

Also of interest: Widmanstätten patterns.

You'll see it on some ancient meteoric iron work. Looks pretty cool.

erisianon Studies find automatic braking can cut crashes over 40%

Fuck no. I had to deal with a rental that had driver assist technology and it damn near killed me. There was a boulder on the road around a blind corner and the car fought me trying to swerve out of the way, I barely avoided it.

Imagine auto braking on black ice or because of a faulty sensor. We're giving immature technology too much control of the vehicle.

erisianon 'Be' is nice, end of story

Cool story I heard about Be once: the engineers could override their managers and had final say.

erisianon .io Domains Considered Harmful

The worst I can say about .io is that it's a fad TLD for software projects from about 10 years ago.

The best I can say about .io is that nvim uses it.

erisianon Coral restoration goes big

Fun fact: mass extinction events in earth's history coincide with worldwide coral bleaching events.

erisianon CRISPR cancer trial success paves the way for personalized treatments

I'm so sorry. My mom was diagnosed a few years ago and she got preyed on by snake oil salesmen to the tune of 6 digits. The money doesn't matter to me, but people are really fucked up.

I can recommend Duke's neuro-oncology center though. They did a great job with her when Sloan Kettering wouldn't touch her.

Best of luck to the both of you and hang in there.

erisianon CRISPR cancer trial success paves the way for personalized treatments

Not CAR-T or CRISPR AFAIK, but there's been some recent breakthroughs with getting treatments past the blood brain barrier, and promising glioblastoma treatments are in the pipeline as well. This is just what I've seen on the internet news, you'd find more than I know about it with some internet searches.

I hope you aren't affected by GBM. If you are, or someone you know is, my only advice is to live life to the fullest while you can and don't let yourself fall into denial of the prognosis.

erisianon CRISPR cancer trial success paves the way for personalized treatments

Pharma typically spends a lot more on marketing than research. In fact, there is little to no correlation between research costs and the cost of a drug.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559086/

https://www.wired.com/story/drug-research-pricing/

https://www.washingtonpost.com/news/wonk/wp/2015/02/11/big-p...

https://www.cbsnews.com/news/higher-drug-prices-support-prof...