Because I feel like the article makes a pretty good case for the benefits of studying optogenetics. These three paragraphs in particular succinctly outline that case:
Neuroscientists study these patterns of electricity, but they’ve been limited by the imprecision of their tools. Much progress in biology depends on observation, which means scientists need tools to both meddle with an organism’s natural bodily systems and watch what happens. Typical neuroscience techniques rely on electricity, using electrodes on the scalp or implanted inside the brain to stimulate and record from groups of neurons. These electrodes are relatively large and crude, though, and can’t target very specific cells, such as the neurons in the hippocampus that encode distinct memories.
This limitation bothers me. From an engineer’s point of view, the study of living creatures can seem messy. When I’m tinkering with an integrated circuit, I can swap out one transistor and check to see if the chip still works. If it doesn’t, I can be sure the new transistor is responsible for the glitch. In biological systems, it’s far harder to isolate a variable of interest.
With optogenetic technology, we can turn neurons on and off as if they were transistors in a circuit. Geneticists have various ways (which we won’t go into here) to deposit the necessary genes into very specific clusters of cells. With our light-up devices, we can then switch on a particular set of neurons. The neurons react to light within milliseconds, making the result of our tinkering fairly obvious.