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adaptbrian

74 karma · joined June 26, 2014

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adaptbrian··on Trials on veterans suggest ibogaine could provide a new treatment for PTSD
https://pubmed.ncbi.nlm.nih.gov/24905167/

https://www.frontiersin.org/journals/neuroscience/articles/1...

https://www.frontiersin.org/journals/nutrition/articles/10.3...

CBT is on the VA PTSD page.

adaptbrian··on Trials on veterans suggest ibogaine could provide a new treatment for PTSD
I'm working on it, I have to find someone who's not after the money and is well endowned. As no one really benefits other than the patient and we know what drives innovation in this space.
adaptbrian··on Claude for Small Business
Meanwhile they won't let you build outside of the webui anymore, agent sdk blah blah changes bc no one can afford api pricing except Accenture. Was moving all my stuff to gpt this morning. Claude is nuts.
adaptbrian··on Google tools for customizing searches
Modern day seo spam is attributed to Google dumping page rank in American serps starting back in 2018. Brands were propped up by signals others can't emulate and the smart seos realized it was a fools errand to work anywhere except in house at said brands so they could continue to easily spam and not get noticed, collect easy pay checks and sit on hacker news all day.

This take is so tiring to read on HN. GOOG won the FUD WAR with Russias misinfo playbook.

Ohh yea. E-a-e-t.

GOOG doesn't track clicks either..........

adaptbrian··on Enhancing gut-brain communication reversed cognitive decline in aging mice
https://www.frontiersin.org/journals/cellular-and-infection-... https://www.cell.com/iscience/fulltext/S2589-0042(25)02209-6 https://www.sciencedirect.com/science/article/pii/S235277142...

im talking about impacting your microbiome through another animal, not the short term effects from aerobic exercise or BDNF and what that feels like. this experience didnt hit quite like other typical metabolic functions.

great to hear you like BDNF. we all could use more of that.

adaptbrian··on Enhancing gut-brain communication reversed cognitive decline in aging mice
It certainly anecdotal, but feels like you can positively effect your gut microbiome for example by riding a horse. Ive read research about how other mammals can share their microbiomes with humans, if its not the horses biome then what is it that so satisfingly calming post ride. Would love to be enlightened. Ride a horse if you need to destress, amazing creatures.
adaptbrian··on Google de-indexed Bear Blog and I don't know why
B.c they shifted their internal KPI in 2018 roughly, to keeping users on Google and not tuning towards users finding what they are looking for ie. Clicking off google.

This is what has caused the degradation of search quality since then.

adaptbrian··on Intro to BirdNET-Pi: Eavesdropping on my feathered friends
This is awesome.
adaptbrian··on Scientists are discovering a powerful new way to prevent cancer
See lambdabas comment right below this. This fella that I linked was the OG on this. Consider this further reading and potentially insightful in parallel to this article.
adaptbrian··on Scientists are discovering a powerful new way to prevent cancer
Warburg effect (oncology) - https://en.m.wikipedia.org/wiki/Warburg_effect_(oncology)
adaptbrian··on Non-Concussive Head Impacts and Brain Microstructure, Chemistry and Function
As we better understand how the brain works we should be adapting sports based on our new findings. The brain is super complicated and still very much not understood.

I have 2 kids who play competitively and I've enjoyed seeing them wait to do headers tell they were older but ide go a step further, headers off punts should be illegal, that would help the majority of hard headers throughout the game. The gravitional force off a punt has to be much higher than a regular field of play header.

Even at 14 most of the kids are like why head that when I can trap it and get up field under more control.

Most kids who've held off heading tell later I feel like get better at using other parts of their body.

Limiting headers to cornerkicks, or heck, ban headers, I doubt soccer players would care. It's a game of feet anyways.

adaptbrian··on Schizophrenia is the price we pay for minds poised near the edge of a cliff
I'm all for getting illicit drug users out of jail, that's social progress. There needs to be more education and attempt at shoring up mental health in the public sector and not just kicking everyone into a room and calling it a day, like the problem is solved.
adaptbrian··on The AIpocalypse is here for web sites as search referrals plunge
People need to corroborate facts you can't do that with just a box, you need someone else's UI to shape the trust you are talking about. That can't be done by showing a simple favicon next to a blob of text.
adaptbrian··on The 'white-collar bloodbath' is all part of the AI hype machine
Lots of tech folks get burnt out without knowing it. If you're tired all the time drastically alter your diet, it could change your life for the better.
adaptbrian··on FDA Clears First Blood Test to Diagnose Alzheimer's
This is crazy the science has since been debunked and the fda clears it?

Someone with more understanding of how the fda process works will need to chime in, how can this happen?

adaptbrian··on GenZ grads say college degrees a waste of time/money as AI gets into workplaces
I just cut 30,000 in managed services b.c I can self host the solution myself on a 300/yr droplet. The folks that were servicing us in the 2nd year (india) won't have the account now since I can do it myself.
adaptbrian··on Google’s two-year frenzy to catch up with OpenAI
We need more ai overviews because look at all the likes! ...... (word to the wise it's a simple link traffic siphon on advertisers)

Kent W. said to hurry up, hmm I could only wonder why, what could he possibly see on the legal horizon.

adaptbrian··on Google Being Forced to Sell Chrome Is Not Good for the Web
It 100% wasn't an 'option' if you wanted traffic as a publisher for a solid period of time
adaptbrian··on Migraine is more than a headache – a rethink offers hope
To hell with the drugs that they throw at you for headaches. It's your diet, lifestyle and poor sleep that's drives this bus.

I'll save you 10 years of my suffering and the awful side effects induced from the cocktail of drugs in this article and say I've reversed cluster headaches and can now tell when anything is not good for my body goes into it.

I did an elimination diet, I skip breakfast usually, and did 1 successful session of hyperbaric oxyegen treatment and it's completely changed my life.

Ive been able to continue ketosis periodically and am adding foods back now 1 by 1 to see what induces pain and believe it or not your body will tell you.

My latest revelation was legumes which tricks you, high in carb item that apparently is a different type of carb that doesn't digest in the bottom of your gut like other carbs. (1)

This list of positive side effects can only seen as a miracle to me from being on the edge of survival (my clusters were headed towards a manic state)

-I don't get down and cynical at all like I used to -my daily energy is a magnitude of about 5x stronger -confidence and positivity are the first reactions i have now so it's greatly uplifted everyone around me - there is a level of even keel rationality that I have now that I've never ever had - just alot more calmer overall and easier to get the busy mind not to overworry

I've tried many drugs and techniques but everything felt like a bandaid on the problem and not actually addressing it

Big and large psychedelic doses, triptans, cgrp, mood stabilizers, steroids. If they had it i tried it.

It took about 1 month of major diet changes to start feeling better. A year in now and the two things that feel the worst for setting off mild nero inflamation are 1-not getting good sleep and 2-eating highly processed foods

Your mileage may vary, everyone reacts to food differently.

1 - https://www.frontiersin.org/journals/nutrition/articles/10.3...

adaptbrian··on What's happening inside the NIH and NSF
The financial incentives a specialist headache doc has whos spent the time and money to get to where they are would never tell a patient to eat less and radically adjust your diet for your ailment to go away, they wouldn't have patients coming back to them and they would go broke (that education was super long and expensive). I like the uncanny idea of getting rid of training requirements and let the free market handle it.

That kind of change though would leave someone with the bag and tends to never get voted or happen so we stay stuck in the over priced pharma, insurance, beating around the bush health game were in. Everyone is incentivezed to keep the bandaids rolling. Don't tell people their drug habits (I mean eating habits) are killing them.

Ohh wait, we got a new pgp blocker for you!

How about just skip breakfast.....

adaptbrian··on Scientists uncover how the brain washes itself during sleep
Male here. Elimination diet going down to single ingredient foods -> talk therapy -> oxyegen therapy -> steady weekly ketosis -> after a year adding back in low inflammation foods, prioritizing carbs from beans like lentils to help repair the gut and now I can give a motivational speech like Tony Robbins from being at a place of basically suicide/ruminating thoughts that never end and cluster headaches that were growing into a chronic, never going away condition.

Everyone's obviously different and your mileage may vary but at the end of the day you can drastically feel different by heavily modifying your diet and pushing past hunger 1 time/day.

adaptbrian··on Perplexity got ads
It just depends where you consume media. I've never felt so unreachable (via ads) online in 25 years of using the internet for play and work.
adaptbrian··on The Engagement Is Better on Bluesky
Pluggable algorithms, is this being done anywhere else? Dare I call this innovation? Antithesis to everything that is current in social engineering.
adaptbrian··on The vagus nerve orchestrates the mind-body connection
Please don't take this the wrong way but I'm very curious if either of you have heavily modified your diet in an effort to remove part of the pain cycle? A low inflammatory diet might help from my own personal experience with diabolical pain.
adaptbrian··on It took my savings and 14 years but I’m about to beat arthritis
2nded.

Eat foods in a way that can ignite ketosis periodically throughout the month and treat carbs as it's something your allergic to. I have personally (finally after 7 years) started regulating my cluster headaches which is an inflammation problem.

adaptbrian··on An affordable, portable and focused device for music, writing and coding
I would never have clicked on that title nor ever realized something like this existed. Descriptive titles can serve a purpose :)

This thing looks awesome.

adaptbrian··on It's getting harder to die
On the flip side changing diet and it's effects on what folks might have seen as something they can never fix/change without _____ drug, might be transformational.

With that said, my better half can't bend her arm past a certain part on her body, however, b.c of a really small/stupid collision/fall coming down a Tahoe MTN ski run. It always depends on the problem.

adaptbrian··on One Million Checkboxes
Love seeing things go viral off the fediverse, it's not designed to push the end of the spectrum out and more organic examples like this might help bring another layer of user adoption.
adaptbrian··on Can ketones enhance cognitive function and protect brain networks?
That's me as well, getting into ketosis has absolutely changed my life for the better.
adaptbrian··on Source of Google AI summary an 11 year old Reddit comment
Which is crazy to me, folks (at scale) are going to learn to distrust AI responses, why would GOOG be so short sighted here.
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