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Nesco

341 karma · joined May 5, 2020

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Nesco··on Jean-Pierre Serre turns 100
wanted to say this.

Also conceptually it feels just right to use nilpotents to probe the smooth structure. In a way nilpotents are violently smaller than even non standard analysis infinitesimals, as the laters’ powers are incredibly small but never vanishing.

Another way to see this is that it makes Taylor expansion exact by killing terms above a bound so it works naturally with the ecosystem surrounding it

Finally duals are very similar to complex in a way. i can be defined as root of X^2 + 1 = 0 even if it felt impossible initially, the dual number as a non nul solution of X^2 = 0 even if it is as counterintuitive.

Nesco··on Linear algebra done right
For a second pass to linear algebra, “Linear Algebra via Exterior Products” from Winitzki is great
Nesco··on Show HN: Infinite canvas notes in the non-Euclidean Poincaré disk
Pretty cool, I actually explored the same idea several months ago, as you can put a huge amount of information while keeping emphasis on local features

https://paperverse.net/

I see you also hade a similar idea on what happens when you click on an arrow

Nesco··on Sweden becomes a smoke-free country
Last time I went there I saw a founder that couldn’t do an interview without changing zyn pouches every literal five (5) minutes
Nesco··on A successful Japanese trial of a ramjet engine designed for Mach‑5 aircraft
American execs negotiating memory two months ago in Korea?
Nesco··on An OpenAI model has disproved a central conjecture in discrete geometry
You lost me at “except billionaires”. I don’t see how Jeff Bezos benefits from this one much more than let’s say Terence Tao.

Can a tech news stay a tech news, without getting bombardes with leftist subtexts all the time?

Nesco··on Going full AI engineer, not touching code anymore
After a time the codebase feel foreign…
Nesco··on Ask HN: Is the Job Market Actually Bad?
retired?
Nesco··on Zed 1.0
Same, I really want to like Zed but LazyVim covers my every need
Nesco··on Parallel agents in Zed
Conductor is really nice! A feature I would really like would be to be able to automatically configure “direnv allow” in the different shells as I use nix & direnv all the time
Nesco··on Tim Cook's Impeccable Timing
I had this opinion until I actually had a new model and felt the weight difference.

The duality of Man

Nesco··on Ask HN: Any interesting niche hobbies?
Synthetic biology: changing genes or expression of genes in cells, etc
Nesco··on The RAM shortage could last years
What do you mean exactly by “Epstein People”? I thoroughly hope it’s not the 4chan definition of it
Nesco··on The RAM shortage could last years
Liberalism (in the traditional economic sens) likes competition. Capitalism is a mode of production, and capitalists notoriously don’t like competition when they are the incumbents
Nesco··on Ancient DNA reveals pervasive directional selection across West Eurasia [pdf]
First yes it is. The claims that this time period was too short to meaningfully change phenotypes in human populations was not entirely far fetched.

Then to address the elephant in the room - which is the race discourse subtext let’s be honest - it’s highly unlikely that any recent selective pressure on a separated population, which resulted in meaningful phenotype adaptations, happened similarly everywhere at the same time

Nesco··on Landmark ancient-genome study shows surprise acceleration of human evolution
“What scientists are wary of is how any discussion in the field gets jumped on and twisted into ammunition to reinforce racist beliefs”

Yet nothing ruined the reputation of the scientific establishment more in recent time than their tendency to change their behaviours and adapt their beliefs for political motives

Nesco··on Ancient DNA reveals pervasive directional selection across West Eurasia [pdf]
There is a graph arguing “intelligence” has been positively selected in west Eurasian population in this paper according to a polygenic score (page 8 fig. 4)

Now I would be quite curious to know how they constructed this polygenic score

Nesco··on Ask HN: Any interesting niche hobbies?
Synbio but it’s expensive as hell
Nesco··on DRAM pricing is killing the hobbyist SBC market
Latin America isn’t a country and Venezuela wasn’t developing in any sens of the word
Nesco··on DRAM pricing is killing the hobbyist SBC market
What country would be the stereotypical example you are thinking of? I fail to find any
Nesco··on Show HN: Paperverse, an Hyperbolic Presentation
Well, this has been entirely vibecoded, so not sure the code itself has any value. It's a 2K line index.html that you can check here if you wish too: https://github.com/nesco/paperverse
Nesco··on France's homegrown open source online office suite
Which it can’t. There is nothing to disagree about. With current demographics projection no amount of taxes can cover welfare states
Nesco··on GPT-5.2
Wait, isn't Devstral2 (normal not small) 123b? What type of laptop do you have? MacBooks don't go over 128GiB
Nesco··on Ask HN: What Are You Working On? (Nov 2025)
Thank you for your hard work. I don’t have a lot of time right now but would love to try to contribute to FreeBSD early next year
Nesco··on Ask HN: What Are You Working On? (Nov 2025)
Created a tiny tech blog aggregator, after noticing the same blogs appeared over and over on HN’s front page: https://techblo.gs

It was mainly an excuse to learn Go to be frank.

Also to anyone reading this I am taking any blog suggestion you could have

Nesco··on Ask HN: Who wants to be hired? (November 2025)
Location: Paris, France

Remote: Yes

Willing to relocate: yes

Technologies: Python, Typescript, Go, React, FastAPI, etc

Résumé/CV: https://drive.google.com/file/d/16H7288XVqhjbdmjkJA2wm0SPbA_...

Email: emmanuel@federbusch.fr

Hi, I'm Emmanuel. I have 5+ years of experience in software and product. I like smaller companies and fast paced work environments. Feel free to send a mail or a PM if you have any questions

Nesco··on Show HN: Arc – high-throughput time-series warehouse with DuckDB analytics
Arc Browser, Arc Prize, Arc Institute and now the Arc Warehouse

I am afraid “Arc” became too fashionable this decade and using it might decrease brand visibility

Nesco··on Ozempic shows anti-aging effects in trial
Let’s be real: both of us have no idea of how it would play out. Pharma companies will try to add them to their stack at some point, and then the real world data we currently lack will decide for everyone
Nesco··on Ozempic shows anti-aging effects in trial
Uncouplers are particularly useful to make sure your metabolism doesn’t slow down, which makes getting off those drugs when reaching the right body fat percentage without regaining everything way easier
Nesco··on Ozempic shows anti-aging effects in trial
Yes, but also BAM15 and mRNA based UCPs overexpression

Longer term if it works more research in the domain, including variations of the other well known ones (DNP, XCT-790, mitoCCCP, …)

I firmly believe that combined with:

- additional progress on the current targets (GLP-1, GIP, …)

- compounds to counteracts muscle loss like myostatin inhibitors

- food options being shaped by more health conscious consumers

Having a slow metabolism will stop being an disadvantage by midcentury

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