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MDS100

100 karma · joined July 19, 2012

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MDS100··on The Science Behind Coffee and Why it's Actually Good for Your Health
Overload /limitations to adaptation.
MDS100··on The Extraordinary Science of Addictive Junk Food
TEF: 20-30% is not negligible. There is even a group of scientist trying to change the default value to 3,2 kcal/g.

Yeah, weight loss is greater because of the bigger WATER loss. (1g Glycogen = 3g Water) Which results in greater intial weight loss. Besides the possibility of low carb being a better treatment for adipose patients/people suffering from Metabolic Syndrome.

"In short, whatever facts anyone wants to bring up, there will always be more that either disprove, or at least throw them into doubt." > Mostly, if you don't know what you are talking about and haven't dived into the actual primary literature. Most just lack some basic domain knowledge and read some Taubes. Now they think there must be some big controversy with carbohydrates and low carb going on. Meh.

Self experimentation is great if you use a non retarded approach. I find too many people trying to reinvent the wheel instead of focusing on some basics and then experimenting with how to integrate them into their life/habit.

MDS100··on The Extraordinary Science of Addictive Junk Food
Fats and Carbs don't vary that much regarding satiety. Mostly protein and fiber, as I said.

How adipocytes "should" behave depends on circumstances... Insulin resistance is probably more a defensive mechanism against the deleterious effects of overeating.

"The flawed thinking, that calories burned by the body is a fixed amount that doesn't vary based on calories consumed, is simply wrong." Who believes that nonsense? Of course we have adaptive mechanisms that regulate energy output (especially NEAT) based on energy intake. The kcal in/out model is very much valid. You just have to account for fluctuating variables in the formula.

"The key is that energy expenditures only rise when the calories consumed are not being partitioned for storage. Elevated insulin levels cause storage of fatty acids, and inhibit release of fatty acids from fat cells by triggering them to be bound up into triglyceride molecules." But this does not happen in a vaccum. This does not matter if you undereat. And if you overeat on mostly fat we still have extremely significant mechanisms to store these TAGs independently of insulin : HSL / ASP.

MDS100··on The Extraordinary Science of Addictive Junk Food
People just call clean, whatever they like/think is beneficial. Everything they deem harmful is unclean.

So it's useless. Regarding Crossfit: There are some very valid reasons I think very badly about CF. It has amazing marketing and can offer a great community (though cult-like). But harms a lot of people long term > see comment above.

MDS100··on The Extraordinary Science of Addictive Junk Food
There is needless damaging going on. No screening and a retarded or no progression at all. With bad technique. If it would be just useless training, that would be ok. Most Fads are like this. But this actively harms people : see high rep box jumps and Achilles tendon ruptures, kipping pull-ups and SLAP lesions and high rep Olympic lifts and broken bodies. Short term results by pushing hard and resistance training for the first time in their lives. Then long term failure.
MDS100··on The Extraordinary Science of Addictive Junk Food
I think you are mixing up high volume pump training with HIIT.

If I say I swim, but I actually bareknuckle fight with other guys. Would it be correct to call this "swimming"? Kind of weird to just rename an activity. Regarding empty stomach: http://examine.com/faq/is-it-better-to-do-aerobic-exercise-f...

MDS100··on The Extraordinary Science of Addictive Junk Food
Meh, the degree of processing can be hard to measure. Yes, I agree. But it's far more useful than clean and unclean. Because these are fantasy.

http://www.sciencebasedmedicine.org/index.php/should-you-be-...

People just call clean, whatever they like/think is beneficial. Everything they deem harmful is unclean.

MDS100··on The Extraordinary Science of Addictive Junk Food
Fish oil, via EPA or DHA, has been implicated in acting as [1]:

An anti-inflammatory An anxiolytic A brain booster A heart health compound A liver health compound

How is this misleading? See: http://examine.com/about/#support

Trans fat page is in the works AFAIK. Also it's mainly a supplement site. (wiki for the evidence on supps) FAQ is just a useful addition.

MDS100··on The Extraordinary Science of Addictive Junk Food
Oh we do have answers on many questions. Just not 100% sure, because detailed experiments on humans are kind of hard to get through the ethic committee. Reading the available Pop science books/articles on nutrition however will probably just confuse people than help them.

What kind of questions do you have?

MDS100··on The Extraordinary Science of Addictive Junk Food
Oh dear, intervall training. http://www.bodyrecomposition.com/fat-loss/stead-state-versus...

Spillover can be very significant, regardless of training. It depends on the makeup of the trainee. The body doesn't work like that (first muscle, than fat) for most people. It's a constant flux in and out of the cells and the overall trend over weeks and months matters for your body composition. For that reason muscle gain (as a more advanced trainee) tends to require some with fat gain if you want progress at any decent speed (Leangainers often don't). Why wait for a couple hours btw? There is no magical switch flipped, which prevents fat gain after waiting a bit longer. You probably misunderstood how important some of the processes after a high intensity training session will be for body composition. Read the article above for an explanation.

Depends on caloric density. I have no problem overeating vastly on good ice cream or nuts& dried berries. Easy to get down an additional 3000kcal.

MDS100··on The Extraordinary Science of Addictive Junk Food
@enraged_camel: Yes, agree. Ad lib it's far easier to not overeat. My point being, that "clean" is too vague and misleading. Why not say unprocessed.

Agree on the crossfit comment.

MDS100··on The Extraordinary Science of Addictive Junk Food
Yeah, you are referring to insulin sensitivity and calorie partitioning. Still depends on genetic makeup (insulin sensitivity can vary 10-fold). P-ratio isn't the same for everyone. So not correct what you are saying (energy does not only go into muscle cells). You can still get fat(ter) with such a diet. Muscle and liver glycogen will be full at some point and more and more fatty acids will be stored in adipocytes. Berkhan got fatter when he overfed. Kcal still need to be controlled.

Also you can get fat on a very low carb diet if you eat too much fat/energy. As a lot of low carb "gurus" do (such a jimmy moore). As a biochem major you should be aware of other mechanisms besides insulin. (ASP & HSL) Insulin is so terribly overrated.

MDS100··on The Extraordinary Science of Addictive Junk Food
http://examine.com/faq/is-saturated-fat-bad-for-me.html
MDS100··on Show HN: Twosome - app created originally for my girlfriend
You are deliberately misinterpreting to get some pity and avoid the hard work of changing what you can control. Life is not black or white. Women do have very similar problems to men. With your attitude you'll just filter out the people that will treat you like shit (because you expect them to treat you that way).
MDS100··on The Extraordinary Science of Addictive Junk Food
Oh god. What the hell does "clean" mean. That's orthorexic nonsense. Unprocessed foods can be very helpful, but they aren't magically different kcal, If you eat too much potatoes and nuts (instead of cake) you'll still gain the same amount of fat (controlling for fiber and protein energy loss). http://www.wannabebig.com/diet-and-nutrition/the-dirt-on-cle...

Regarding fructose: http://www.alanaragonblog.com/2010/01/29/the-bitter-truth-ab... http://weightology.net/?p=434

Gluten is extremism overhyped, but sensitivity to it can be a problem.

MDS100··on The Extraordinary Science of Addictive Junk Food
You are wrong. Too much energy dense food makes you fat. Fat will make you fat if you overeat (because the fatty acid molecules from your food will be stored in your fat cells). It's not as easy as "more carbs" = obesity epidemic. There are many more factors, most important being inactivity and overconsumption of food. The carbohydrate hypothesis is very clearly Bullshit: http://wholehealthsource.blogspot.de/2011/08/carbohydrate-hy...

When people go on a low carb diet they: a. restrict their food intake by restricing their choices (less processed foods if you exclude a massiv part of " b. increase protein intake (protein has a higher thermic effect than any other macronutrient and drastically cuts down total kcal consumption in ad lib feeding trials by reducing appetite)

You can do something similar with a low fat diet (on which another part of the population will feel better - skewed towards more active and leaner people).

Low carb (whatever that means - not clearly defined) isn't a better choice for your health than a mixed diet with a high(er) protein intake. If it works for you: great. But that doesn't mean calories don't count and carbohydrates/insulin cause obesity. Nor that it works for everyone.

MDS100··on How To Buy Your Way Onto The New York Times Bestsellers List
For the good bits, there are better sources. Nearly everything contains some good bits.

The problem lies in intentional deceit. Tim is a smart guy and had access to very accomplished, smart people. Very unlikely that he can't think critically about some of the nonsense he puts out. For example he gets very basic physiological mechanisms astonishingly wrong and can't reach his own fitness or language goals with his own advice.

MDS100··on Good sleep, good learning, good life
Yes, this exactly.
MDS100··on Show HN: Twosome - app created originally for my girlfriend
Who cares what most couples/women are like. You are on here, so you'll tend to find a very small proportion of women attractive. (presuming higher than average intelligence) If you are proactive enough to choose in your dating life, you wouldn't complain about the culture. That's just externalizing the sources of your problems.

"If I'm upset, it's just because I happen to lose out in today's culture." Make the most out of yourself and play the numbers game. The culture is better than at any point in the past. More choice, more freedom for both sides (it's not a war or a competition - everybody wins). You just "loose" if you don't invest in yourself and overcome fears.

MDS100··on German Fascination With Degrees Claims Latest Victim: Education Minister
Also americans just don't value Intellectuals/Education/Intelligence as much.
MDS100··on Don’t Take Medical Advice From the New York Times Magazine
Depends on the pills. Melatonin for sleeping is great for example: http://examine.com/supplements/Melatonin/ http://examine.com/blog/better-sleep-probably-no-caveats/
MDS100··on That Daily Shower Can Be a Killer
No it has been tested. It's only placebo.
MDS100··on It’s time all clinical trial results are reported
I second SBM.
MDS100··on Why You Should Never Skip Flossing Your Teeth
Meh, observational data sucks. And the cohort studies (with treatments) don't seem to have been compared with a control group. Just before/after. Way more important to be lean and active.
MDS100··on Why the Fuck?
How exactly?
MDS100··on A year without caffeine (part 2)
@Newsletter subscriber: Also some other very common quack sign: > Overly focused on nutrition and supplements for healing all kinds of maladies.

> Toxins everywhere

> Fear mongering

Seems very much you are wasting your 7$: http://www.sciencebasedmedicine.org/index.php/your-disease-y...

His formula doesn't make any sense. Health=micronutrients/kcal is a useless approximation. Implies that if you reduce kcal by switiching to more micronutrient dense foods, you'll always be healthier. Which is untrue (there are problems such as starvation, hypervitaminosis, drinking saltwater would be a great idea...) and highly depends on a plethora of other factors.

It's pseudoscience.

(And I say that as a future MD who also does science based sports/nutritional consulting, so be assured I know of the importance of diet and exercise in disease&health.) There are far better sources out there.

MDS100··on How To Lose Weight And Influence People
Yes. http://www.ncbi.nlm.nih.gov/pubmed/17413101 http://www.ncbi.nlm.nih.gov/pubmed/1989409 http://www.ncbi.nlm.nih.gov/pubmed/1734671 http://www.ncbi.nlm.nih.gov/pubmed/8968851

Also: http://ajcn.nutrition.org/content/79/5/899S.long

MDS100··on How To Lose Weight And Influence People
"All the matters is: can you impose a long term deficit? Whether by paleo, keto or any other dietary method, the sole long term determinant of average body mass is net caloric balance." Average body mass (!), not body composition etc. You need to actually read his assertion. He is completely right.
MDS100··on How To Lose Weight And Influence People
Honestly, you are just burning a bunch of done-to-death straw men. (esp. the common "only thing" vs. "most important") Obviously the effects will be different.

But the first and most important (!) factor for body composition and fatness is still caloric balance. As confirmed by a vast amount of experimental data in real humans under controlled conditions. Which is Jacques Point. Macronutrients (as well as micronutrients) do have very significant consequences (Leptin, Insulin blabla.). But that won't help at all if caloric intake/output don't match your goal. It seems you read some of that nonsense Gary Taubes & co perpetuate?

Source: I'm a med student & fitness professional, who also writes fitness books. And gets results.

MDS100··on The Real Hazards of E-Devices on Planes
"Turn off your mobile phone because it may reduce the risk of firey death for 170+ people? "

Does it really?

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