FollowingTheDao

It’s not that lowering cholesterol does not decrease heart disease, but the fundamental problem of heart disease is not cholesterol, it’s the inflammation.

Lowering cholesterol lowers the amount of oxidized cholesterol that is caused from inflammation. The fact is is that in inflammation is the fundamental disorder, not high cholesterol on its own.

I bought an iPhone 16e which I am about to sell, not only because of iOS 26 (horrific looking and battery drain), but I did not know they switched to only eSIMs. I have a flip phone which I like to use when I have no need for a smart phone. Now there is no way for me to switch. Plus, I know when I take out my SIM there is no way any one is tracking my phone.

eSIMs just another way these companies are trying to control, and as you said, profit, off of their customers.

I see this as taking ownership away from the customer as well. I no longer own the SIM in essence.

I see cancel culture is still alive and well...

It’s not secret , it’s published widely and I read it often. Here’s an example of how much cheaper Canadian farmland is an American farmland.

And your farmland is not only cheaper, but it’s more productive.

You can’t compare the United States and Canada because we have different political systems. I mean, you guys get free healthcare. You can probably afford to buy land because you’re not spending all your money on outrageous insurance premiums, or out-of-pocket cost from going to the doctor.

https://www.producer.com/news/prairie-farmland-still-a-barga... Western Canadian farmland is cheap when compared to Europe and the United States, says the director of an investment fund with offices in Calgary and Toronto.

You don’t understand America because you don’t live in America. Monopolies drive up land prices to squeeze out people who can’t afford the land.

Maybe we should nationalize farms so no one has to be hungry?

Cartels.

You seriously think these 400+ farmers that attended this meeting got into trouble because they bought “new toys“?

There’s a monopoly in farming like there’s a monopoly in tech. And you think you can go into tech with some niche business and somehow become Google before Google buys you up? Well, that’s the goal, to just have a company to have a bigger person buy you up and then you go away with the money and everyone else suffers.

There’s an insane separation of wealth and you don’t see that as a/the problem? I’m serious with these questions.

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It is true that early man specifically during the Ice Age, had a much higher omega-3 diet. But many of you are not genetically ice age people. I know I am because of my haplotype, which is K1.

Most European Caucasians would probably do better on a high omega-3 short chain poly unsaturated fatty acid diet. Like the omega-3’s from flaxseed. The change from gather cultures to farming culture changed the way we processed polyunsaturated fatty acids.

I’d really be interested in hearing what your heritage is, specifically on your mother side. If you read my other post, you’ll understand why I’m curious.

The best source is always going to be from fish. That’s because it comes with other things such as calcitonin and D3.

I agree with all you say here. I’ve been studying this for over 15 years because my family suffered from early heart attacks, like below 50 years of age. My brother died of a heart attack at 48.

This heart disease risk along with psychiatric problems my family, including suicides led me to getting my genetics. Once I had them, it became clear how much I need long chain poly unsaturated fatty acids and specifically higher omega-3 than the normal European Caucasian population.

This is primarily because of polymorphisms I have in two genes FADS1 and FADS2.

Currently, I pretty much eat negligible amounts of short chain poly unsaturated fatty acids. The major components of my diet are cold water seafood, and muscles and oysters. Plus a lot of seaweed (this is from another prism I have, I am a FUT2 non-secretor. I also eat a very low amount of carbohydrates.

Now I’ve had serious psychiatric problems in my life. Three attempted suicides, for hospitalizations, and I was on a ton of medications. But guess what, I’m no longer on any medication‘s, my blood pressure has normalized, and my lipids are normal. And I can’t count the other of other minor bothersome symptoms I’ve had that have vanished.

No, I am a huge outlier, but I am also sort of a canary in a coal mine. Because while I am extremely sensitive to deficiencies of omega-3 fatty acids. Anyone who does not get at least the minimal amount of polyunsaturated fatty acids will end up having health problems. Whether you need long chain or short chain polyunsaturated fatty acids is going to depend on your genetics.

My genetic haplotype is K1, which is uncommon for Europeans to have. The dates back to over 10,000 years ago during the Ice Age. I also seem to have a lot of finish heritage, which I can possibly trace back to the Sami people who are a very high fat high omega-3 diet.

But anyway, you’re right, this is not a number. You should guess that because omega-3‘s can really thin out peoples blood. I need this but for other people this might be a huge problem.

No, you don’t need a centralized government in all social systems.

Centralized government is the big distinction here. Libertarian socialism of a decentralized government.

I’m sorry you’re missing my point. If a culture grows up eating a lot of long chain poly unsaturated fatty acids, and then suddenly they stop, then the myopia develops.

In populations that depend on a very heavy vegetarian diet, which is comprise primarily of shortchange, polyunsaturated fatty acids, they might have other issues not related to myopia when they go off of their traditional diet.

Myopia in my opinion is a result of the industrialization of food.

Both of these cultures are genetically adapted to the foods they need. So comparing these populations will not reveal anything about myopia in certain populations.

I take fish oil and eat seafood for this exact reason. I probably get 4 to 5 g of omega-3 a day at least. And that really moved all my lipids in a positive direction.

I believe you. People really don’t understand how important omega-3 is for the transport and metabolism of neurotransmitters.

https://pubmed.ncbi.nlm.nih.gov/16963244/

Although high omega-3 with saturated fats may protect against the effect of only a diet high and saturated fats.

If I was not on my phone, I would look up the studies on this. :)

I disagree, I think they need to study specific populations for specific diseases associated with different diets. If you study this across population where this doesn’t matter as much then they will say omega-3 has no effect on nearsightedness, which is bad for the population that needs omega-3.

Omega-3 saved me from the fate of my family, dying from a heart attack before I was 50.

And I see this need in my genetics, specifically FADS1 FADS2 polymorphisms that make me need higher chain omega-3 fatty acids like from seafood.

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But maybe you should be angry? Anger is a great motivator for people to change governments and policies.

Maybe the real source of anxiety is people have justified anger but no where to direct the anger to affect change?

Maybe it is better to keep reading the news and organize people to make it so we do not have any bad news to report.

Heat Shock Proteins affect the function of all of those systems . Put that into OpenEvidence...

Learn about biology instead of relying on simple searches for you answers.

And lobbyists are also directed at those policy makers...which is the bigger problem.

Big spikes in soft money group spending in 22 and 24 elections...

https://www.opensecrets.org/industries/indus?cycle=2024&ind=...

> It also reduces the world's dependence on unstable regions.

Do you think the world might have made these regions unstable because they have the oil?

Good question, but I will say yes just based on the science I know. The type of pollutant does not matter, it is whatever effects heat shock proteins to effect protein folding.

Heat shock proteins (and cold shock proteins) are affected by more than temperature, but temperature is really important as well.[1][2]

[1] https://pubmed.ncbi.nlm.nih.gov/21848409/ [2] https://academic.oup.com/biomedgerontology/article/80/4/glae...

I am homeless, I live in a minivan, and I have a solar battery charger with a small carbon filter/HEPA air filter that I use every night and it helps me so much. I am a very "sensitive" person to many things in the environment, but many times while traveling i find myself in the midst of wildfire smoke. (I also carry a facemask respirator for the same reason).

In my opinion, the reason air pollution effects dementia risk is through activation of Heat Shock Proteins and I think it is the most valuable place to be investing in research.

Heat Shock Proteins in Alzheimer’s Disease: Role and Targeting

https://pmc.ncbi.nlm.nih.gov/articles/PMC6163571/

I agree, but no one is more obvious with Musk yet people still keep falling for it. Specifically his “investors”.

While I agree with your take on the harms or AI surveillance, I will never agree that AI is beneficial, and there is a net negative outcome using AI. For example electricity prices, carbon release, hallucinations, cognitive decay...they all outweigh what benefit AI brings, which still is not clear.

Like nuclear fission, AI should never have been developed.