FollowingTheDao

I agree, even though he was way off on his thinking at least he tried something. The doctors told my father to go ion chemo because it would give him 2 yeras vs the 1 year he was facing with his pancreatic cancer. My sister, a oncology nurse told him not to do it, but he id. The chemo ended up causing a bile duct blockage which killing him after six months.

It is because of what Jobs did we know what not to do.

> Why does Linus Torvalds get a pass

Because he does not make a ton of money. Only a measly $150 net wroth compared to the $10 billion of Jobs.

People put up with asshles in a hope they they will get some of that stinky money.

If Steve Jobs were on HN he would be ruthlessly downvoted.

I wish he did not smoke [4], or convert to a largely fruit diet [1,2,3,5], they both most likely caused his pancreatic cancer.

My father died of pancreatic cancer, he smoked for most of his life and ate a ton of honey. I see it in my genetics (ABO, SOD2) and luckily I quit smoking when I was very young and could never tolerate sweet foods. I also eat a high manganese diet (the cofactor for ABO), lots of mussles, and take it as a supplement on occation.

I wish Jobs were still alive, I would probably not want to sell my iphone right now because of liquid ass.

[1] https://www.uclahealth.org/news/release/pancreatic-cancers-u...

[2] https://www.aicr.org/resources/blog/glucose-fructose-and-the...

[3] https://pmc.ncbi.nlm.nih.gov/articles/PMC10722142/

[4] https://pmc.ncbi.nlm.nih.gov/articles/PMC5455596/

[5] https://finance.yahoo.com/news/steve-jobs-followed-extreme-d...

This is such a ridiculous argument. They could have read five papers, couldn’t they?

Awesome for you and props! Let me tell you, doctors will gaslight patients who cure themselves because it is some kind of mental disorder they have I cannot figure out. They said THE EXACT SAME THING to my friend who also cured his UC with diet. "Well, you never had it because if you did you could not cure it." He is a Dentist and he literally yelled at them because he knew how unscientific it was what they were saying.

I am a FUT2 non-secretor who suffered with IBS-D for years. I had to cure myself as well. Very strict diet and high seaweed (it contains fucose (not fructose)). Not one doctor cares. I tell you, it is a mental disorder.

Crohn's is most certainly started by E. Coli infection...

https://www.gastroenterologyadvisor.com/news/escherichia-col...

What????

We knew that LolCDE was a vulnerability to e coli since well before 2016 and knew inhibitors of the complex, globomycin being one of them, which they knew about since 1978

https://journals.asm.org/doi/full/10.1128/jb.00502-16

https://pubmed.ncbi.nlm.nih.gov/353012/

Is enterololin just another from of globomycin?

Is AI smart or are scientists just getting dumber?

> Because evolution doesn't care about us beyond reproduction age (after which is when most cancers occur, especially considering that historically that age was between say 16 and 35).

This is the lie that needs. to die. Elder people were very important in even the most primitive societies. "lifespan" was low in pre-history, not because no one lived long lives, it was because infant mortality was very high.

https://sc.edu/uofsc/posts/2022/08/conversation-old-age-is-n...

> it seems our systems are balanced to regulate cancer during our youth and reproductive years

Yes, the most important question, and an easy answer if you know where to look. What is it that we lose when we age?

Mineral and vitamin deficiencies can accelerate the mitochondrial decay of aging

https://pubmed.ncbi.nlm.nih.gov/16102804/

Age-associated B vitamin deficiency as a determinant of chronic diseases

https://www.cambridge.org/core/journals/nutrition-research-r...

Emerging Roles of Vitamin B12 in Aging and Inflammation

https://www.mdpi.com/1422-0067/25/9/5044

There is more if you want to look. Lots more.

Discovery? HA! Traditional Chinese Medicine already knew the body cures cancer by boosting the immune system. Did they no how? Who cares?

Harnessing the power of traditional Chinese medicine monomers and compound prescriptions to boost cancer immunotherapy

https://pmc.ncbi.nlm.nih.gov/articles/PMC10684919/

Antitumor effects of immunity-enhancing traditional Chinese medicine

https://pubmed.ncbi.nlm.nih.gov/31710893/

Edit: Please comment on what is wrong if you will downvote this because I am open to discussion and correction.

Modern society only patents things that were already known and then makes them out of reach for the common man.

There is a big difference between acute inflammation and chronic inflammation.

Infection causes acute inflammation. Air pollution causes chronic inflammation.

Infection can also cause chronic or out of control inflammation which can aslo kill you via a cytokine storm.

But my question is; what are the algos trading on? what data, what news?

Yes, is the tiny 25 bp decrease in the Fed Rate we just had partially responsible for this sudden uptick in equities? If so I think it marks a kind of desperation. If there is no where else to invest, like tresuries, they push it in every other market you can.

Or, do they know the job report that did not come out this week is horrible and this is the insider pump before the dump? The Shiller price-to-earnings ratio has climbed to 40.08. Insanity like .com bubble.

More from:

https://www.msn.com/en-us/money/economy/the-credit-market-is...

"The overarching concern on Wall Street is that the exceptionally high valuations for corporate debt are concealing excesses in the market and insufficiently compensating investors for taking risks."

If you look at the reaction to the markets the last two days, it makes no sense, adn this is why. It is just investor insanity out there right now. Gold as well keep breaking record highs at the same time the stock market does. Again, makes no sense, unless you think the market is in a huge bubble.

I will bet there is a dump in bitcoin coming.

Signal is next,

And you don’t think you’ll be marked as suspicious for leaving your home phone at home?

Why did you leave your phone at home? What are you hiding? Why are you afraid of being tracked by us?

Do you not understand anything about privacy and why it’s important?

Do you think they’re not gonna use this on you next?

For the last time. I am not saying that lowering cholesterol does not lower the risk of CVD. I am saying that it is oxidized cholesterol that causes CVD, and by lowering cholesterol you are also lowering oxidized cholesterol. Cholersterol good. oxidized cholesterol bad.

pubmed.ncbi.nlm.nih.gov/18625445/

Oxidative modification of low-density lipoprotein (LDL) is one of the earliest events in atherosclerosis.

https://www.frontiersin.org/journals/cardiovascular-medicine...

The point of the original article is we should be focusing more on lowering oxidative stress (inflammation) instead of focusing on lowering cholesterol since 75% of people who have heart attacks have normal cholesterol.

Also, CVD mortality is lowered, but other causes of death increase.

The dismissal of anecdotal data is why science has been stalled and people are still sick.

The fact that you don’t care if one person who has high, LDL does not get heart disease is emblematic of the problem in healthcare. If one person who has high, LDL does not get heart disease then high LDL alone does not cause heart disease. There is amounts of evidence that LDL on its own, when it is not oxidized by inflammation, does not cause heart disease is something you’re consistently overlooking.

Again, and I don’t know why I have to repeat this, but I know that Laura LDL decreases cardiovascular disease risk, but that is only because if you have lower amounts of oxidized LDL, then you won’t get heart disease. But what do we want to lower, the LDL, which is needed by the body or the oxidative stress and inflammation which damages the LDL we need for our body?

If you don’t understand the difference between acute and chronic inflammation, there is no longer any reason to continue this conversation with you. Yes, I apologize because I didn’t specify the difference, but I thought you would be intelligent enough to know the distinction.

If one person with high cholesterol does not get heart disease then cholesterol is not the problem. Fact. Logic.

Why don’t you stop your appeal to authority arguments and focus on the facts.

It’s not that I haven’t died yet either. My calcium artery score was zero. I have no plaque in my arteries and I’ve had high cholesterol for probably 30 years of my life because of my genetics.

If that is not interesting to you then you have an odd bias. I merely saying that inflammation is the risk factor that matters more than high cholesterol. You can lower cholesterol for someone who has high inflammation and reduce heart disease, but reducing inflammation is more important overall.

Weightlifting increases inflammation acutely, not chronically. But if you work out too much without enough rest, then the inflammation is chronic and that’s where the danger is. Over the long-term resistance training decreases CRP level levels when adequate rest is involved.

To the point of the original article, the consensus is probably doing people more harm than good. My mother had a heart attack at 45. My brother died of a heart attack at 48 and my other brother had a heart attack at 47. My cholesterol has been over 200 for at least 15 years and I’m in my late 50s. My calcium artery scan was zero and all heart sonograms are perfect.

I would worry more about HDL than LDL first of all, because HDL is an antioxidant. And it’s about the oxidative stress, which is only another term for inflammation, that we should be concerned about.

So why did I not get heart disease? Everyone else in my family smoked that had heart disease for a much longer period than I did. I only smoked for about five years when I was younger, but everyone else smoked for over 15.

So it wasn’t cholesterol that killed my brother. It was the smoking that caused inflammation on the body that oxidized the cholesterol that killed him.

These people with genetically low cholesterol, however, have other issues. Familial hypobetalipoproteinemia (FHBL) is a disorder that impairs the body's ability to absorb and transport fats. Many individuals with FHBL develop an abnormal buildup of fats in the livercalled hepatic steatosis or fatty liver.

You have to understand the point which you’re not yet able to put in your head. Yes it is true that lowering cholesterol lowers cardiovascular disease. No one here is disagreeing with that. What we are explaining is that cholesterol alone does not cause heart disease. It is cholesterol plus inflammation that causes heart disease. I don’t know why this is so hard to understand. Lowering inflammation not only would reduce cardiovascular disease, but also cancer, arthritis and a multitude of other diseases.

Lower cholesterol helps but lowering inflammation helps everyone. As I’ve said in another comment over 75% of people who have heart attacks have normal LDL levels.

https://www.uclahealth.org/news/release/most-heart-attack-pa...

And lower cholesterol is not without its own risks. You need cholesterol to make hormones and things like CoQ10, which are important for our health. So what’s better? Lowering oxidative stress and inflammation or lowering cholesterol?

Yes, LDL is the best we have since they won’t bother to measure oxidative stress nor inflammation in the human body.

But lowering your LDL does not prevent heart disease. There are many many people with normal LDL who have heart attacks.

In fact, it is the norm. And I can’t imagine how many people are being told. They have no heart disease risk just because their LDL is normal. It’s a crime and it needs to be stopped.

https://www.uclahealth.org/news/release/most-heart-attack-pa...

A new national study has shown that nearly 75 percent of patients hospitalized for a heart attack had cholesterol levels that would indicate they were not at high risk for a cardiovascular event, based on current national cholesterol guidelines.

Yes, you are correct. Nothing wrong with walking, helps keep weight low and fat cells are a huge source of oxidative stress. Better to eat low calorie, high nutrient dense foods.

Exercise actually increases oxidative stress.

https://pmc.ncbi.nlm.nih.gov/articles/PMC7498668/

What lowers oxidative stress is nutrition, specifically selenium, vitamin C, manganese, zinc, and copper.

CRP is a protein produced by the liver in response to inflammation. Elevated CRP levels indicate inflammation in the bodY.

High levels of CRP are associated with high levels of oxidative stress.

https://pubmed.ncbi.nlm.nih.gov/15585208/

Inflammation is a synonym for high levels of oxidative stress. Keep your oxidative stress low and you will not get heart disease.