1,434 karma · joined September 4, 2019
https://support.google.com/paymentscenter/answer/9028746?hl=...
Because you can't actually change your country on your Google payment profile. You need to create a new one and then switch the new one.
I had to do this to switch my US account to an EU account with the EU GDPR user consent options. Your Google account is tied to the payment profile country AFAIK.
https://en.wikipedia.org/wiki/Church_tax#Germany
" The church tax is only paid by members of the respective church. People who are not members of a church tax-collecting denomination do not have to pay it. Members of a religious community under public law may formally declare their wish to leave the community to state (not religious) authorities. The obligation to pay church taxes ends once such a declaration has been made. Some communities refuse to administer marriages and burials of (former) members who had declared to leave it. "
In many European countries, everyone (community member or not, believer or firm atheist) has to pay full taxes to pay for the churches/synagogues and mosques. Including the salary of priests. This in addition of them also not being taxed due to their special status.
Despite not living in a theocracy, many are forced to participate directly in a cult that might be of zero interest to them.
I've been using it since the end of google reader and it works great. The filtering aspect alone is wonderful for me to filter out some tags/authors.
The (paid official ) Android app is pretty good too and supports offline reading (for a very small fee).
I self host it on a public facing server. Great to sync my reading between all my devices. I do recommend adding some basic auth in front of the (obviously https) login page as the client apps (android) supports it and it adds a layer of security.
5. Cui Bono?
But this is because I think nobody should be fired, de-platformed, banned or "canceled" for opinions/thoughts outside of those contexts.
Sure you could be fired from your work if you started shouting your opinions on your workplace. No you shouldn't be fired from your work for anything that happened outside that work.
Anonymity is needed for the sake of free thinking as a shield to any current/future mob that could ruin your life/career for just any reason at all.
In 10 Years you might find yourself ostracized because someone found some 20yo old snippet of code you wrote with "banned words" in them.
I used to think it was an acquired thing that you could have free opinions with your official identity (political or anything) and not risk your livelihood for opinions but the thought enforcing mobs are now everywhere and most companies will bend the knee to their bidding.
And obviously this identity needs to be decentralized to also protect that identity itself from being ruined by the various de-platforming attempts.
These days, I'm genuinely more concerned about the current mob rule mentality than government oppression.
https://www.mohfw.gov.in/pdf/AdvisoryontheuseofHydroxychloro...
https://www.thelancet.com/journals/laninf/article/PIIS1473-3...
But it's still unpublished at this stage
There have been already many reactions to these new claims. Very quick to dismiss him again for the lack of any control group despite him comparing to other hospitals who do not treat with HCQ...
I'm also not sure they'll give out all patient detailed history but we'll see...
They intended to use it to prevent virus replication in the cells at the early stages of the immune response to allow the immune system to build up a response at a slower pace.
The amount of treatment proposed in Europe is around 5 days of HCQ with about 800mg on D1 and then 400mg on D2-5. This is an incredibly low dosage and will have very little immunosuppressant effect. It takes a very long time to act as an efficient immunosuppressant (1 to 3 months for Lupus).
Expecting HCQ to suppress the immune system for cytokine storms in a matter of hours seems very strange.
As that controversial French doctor said in multiple interviews. If you are already in need of a respirator then your issue is no longer the virus but your own immune system killing you (cytokine storm or added bacterial pneumonia). At that stage, HCQ is not very useful. Not in these dosages at least.
Most people are only focusing on the immunosuppressing effect of HCQ for some reason which is very strange to me.
It takes time for chloroquine to act as a zinc ionophore as well and for zinc to enter the cells (and it needs to be in the cells to inhibit RNA polymerase). As you can see in the studies I posted. Between 24 and 72 hours it seems.
If the virus cannot replicate correctly (with the zinc idea), it might give more time to "flatten the curve" for the immune system. To build up antibodies and respond to the disease without inducing a cytokine storm.
This at least is their hypothesis. And it has not been confirmed in any other way than by observing that those with chronic Lupus+HCQ treatment seemed to be "immune" to the disease. And this was only done in Wuhan as far as I know.
Unfortunately Dr Zhan Zhang has not yet published his full results except for this preliminary https://www.medrxiv.org/content/10.1101/2020.03.22.20040758v...
Which doesn't go into much detail about anything except that "it seems to work". Unfortunately ... Yet I do see logic in the idea.
I just wish people (with access to patient files in major hospital centers) would also look into this and they could maybe confirm this "once and for all" without even needing a full blown trial.
1) Chloroquine (and HCQ) is a zinc ionophore: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182877/
2) Zinc seems to inhibit RNA polymerase of Coronaviruses in vitro https://www.researchgate.net/publication/47794995_Zn_Inhibit...
Their conclusion was that chloroquine could indeed allow zinc to enter the cell and then inhibit replication (and therefore that the treatment needed to be administered early).
Nobody seems to be talking about a very easy way to verify chloroquine (and HCQ) efficiency by just using the same method used in China:
Cross-check the list of patients infected with Lupus (lupus erythematosus) and with chronic HCQ treatment (they take it for years) with the list of known infected COVID19 patients.
In China (and specifically in Wuhan), this is how they (team of Dr Zhang Zhan) found out about the efficiency of HCQ. They noticed that there were no patients with chronic HCQ treatment for lupus (lupus erythematosus) infected with covid19. This was in peoples Hospital of Wuhan University (source: https://www.jqknews.com/news/388543-The_novel_coronavirus_pn...)
This alone would be enough to prove some efficiency even as prophyalxis (as they are advocating officially in India). This should be quite trivial to check with the current amount of confirmed infection.
These details were all explained in this medcram vid: https://www.youtube.com/watch?v=Eeh054-Hx1U
(same study with some minor updates)
These results are very encouraging.