For example, I once posted a job that included the word "Ruby". I thought the job posting made it clear that Ruby was a very, very small part of the job. But I still got several resumes from people who were Ruby experts or at least claimed to be, and that is all the experience they had given their resumes. They had little or no non-Ruby experience. At the time, I needed someone who could write Ruby code but had much more experience elsewhere.
So the resumes helped me screen out those candidates. And I also learned that my job posting was worded incorrectly.