The biggest problem is that the US has shown not trustable when it comes to treaty. You can have a treaty with the US but the US can just use Israel or some other proxy to do the advance research and development for them..
It’s one of the only countries that reliably follows treaties. Unfortunately they are very hard to pass, which is why the agreements falsely called treaties are so easy to reverse - they are all personal executive orders like JCPOA (alas)