> I think it's since been re-implemented
Nope, it is being reimplemented/rebooted and should be released flashless in 2013, but the current version remains flash-based:
> Edmund McMillen has confirmed that he is working on a remake of the game slated for release in 2013. He states that the primary purpose of the remake will be to take it out of Flash, and use a new engine to help limit the bugs with the game. It will feature completely re-balanced items and enemies, as well as redrawn graphics, possible local co-op support, new items, new enemies, and console support. It was announced that it will come with 2 Player Local Co-Op and will be called The Binding Of Isaac: Rebirth.