Just out of curiosity, what are you running on OpenBSD?
I got annoyed with the openssh bugs this summer and figured I should have some hosts I can mostly not worry about.
In general, I think I want OpenBSD to be the Internet-facing hosts as much as possible, so looking into proxy options for TLS+QUIC.
I've used relayd in front of a ruby on rails app that spawns 4 sockets, but I don't see why you would do it for httpd.
Note that httpd is based on relayd and likely still shares a lot of the same code.