Affinity makes some great alternatives to Photoshop and Illustrator (and you only pay for it once rather than monthly). They have a 40% off deal for Black Friday. See https://affinity.serif.com/en-us/
The WineHQ AppDB [1] table doesn't look great, but [2] offers some hope.
[1] https://appdb.winehq.org/objectManager.php?bIsQueue=false&bI...
[2] https://forum.affinity.serif.com/index.php?/topic/182758-aff...
I do use Linux (desktop) quite a lot, but I haven't found anything quite like Affinity Designer for Linux, i.e. GPU-accelerated vector graphics rendering. For simple projects, I often use BoxySVG (which is free on Linux).
For photo / raster graphics editing, I find that Krita meets all my needs on Linux.
Both a PWA and desktop app. Cool!