I've heard there are but haven't noticed anything personally.
Nicotine has antifungal and antimicrobial attributes. I have even seen studies claiming smokers were less likely to get serious covid infections likely due to some property of nicotine.
Native Americans treated tobacco as a sacred plant and praised it for all sorts of health and spiritual properties. That makes me think the plant and its consumption is probably a net benefit and it may be the way commercial cigarettes and tobacco are processed that cause the problems.