So you could grow teeth in-vitro from patient's own stemcells and then implant those. I would be safer and not much testing needed.
So you could grow teeth in-vitro from patient's own stemcells and then implant those. I would be safer and not much testing needed.
How about as recent as George Washington? [1]
[1] https://www.mountvernon.org/george-washington/health/washing...
wild
Yes, a social system in which your involuntary labor all goes to your "owner" and in which you are reduced to selling your teeth for spending money is an abhorrent one.
It's capitalism ad absurdum. Sure, today people are born "free", but they still have to pay money to keep a roof overhead and food on the table, and that same money can be used, say, for dental procedures that could save teeth, so in a way people still have to make choices about whether they'd rather have money or teeth. They just also have more options for getting money. You can still see the impact of these forced choices in poor people's mouths.
The beneficiaries of this indirect coercion -- when restricted to the subject of teeth -- are today mostly dentists, and the actions chosen are mostly inactions (skip treatment, get a cheaper treatment). In those days, the beneficiaries included people who needed dentures, and the actions were less passive: They involved submitting to pliers.
On the ethical spectrum, it's somewhere quite a bit worse than buying a wig made of a Pakistani lady's hair, but better than buying a Chinese prisoner's kidney.
Also seems like there's evidence of the practice going way back to ancient Egypt, which isn't hugely surprising but it's crazy that this is something established for at least as long as good old cruelty-free metal teeth [2]
[1] https://en.wikipedia.org/wiki/Tooth_transplant
[2] https://www.livescience.com/46788-ancient-dental-implant-fou...
(Edit: The history section of your Wikipedia link [1] is interesting.)
Treatment consisted of a breathable dressing which sealed the fingertip around the stump, thereby prevented it from drying out and scarring.
It was very smelly and messy for a few weeks, but it worked - my fingertip grew back.
It's a bit deformed (because the emergency doctor gave me a 'manicure' before dressing the wound), but it's there.
Lots of results on Google if you search for "fingertip regeneration". Otherwise, I can provide academic/medical references.
Is there any known successful case?
Unless you install into fresh socket, the success must have been because of bone-to-bone adhesion.