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>wasm32-unknown-unknown has an ABI incompatibility which means you cannot interoperate between C compiled to Wasm and Rust compiled to Wasm.

Since I was surprised to learn this, and to save everyone else the search, it's https://github.com/rust-lang/rust/issues/71871

Further down that GitHub issue, it mentions the problem has been fixed:

Weirdly though, there's another issue (opened prior) that's ongoing and seems to indicate things aren't fixed after all:

>Further down that GitHub issue, it mentions the problem has been fixed:

No, if you look at the diff, it was only fixed for emscripten and wasi.

Note that this only affects structs that are passed by value, so it’s not always an issue and can be worked around.