This plays out precisely as the blog post details with the split between WASI and Web Platform. Say you want to compile a Rust + C codebase to Wasm and run in the browser. You have three targets: wasm32-unknown-emscripten, wasm32-unknown-unknown, and wasm32-wasi. Emscripten is relatively old and not maintained. It'll work but you get some old JS that doesn't play well with newer stuff. wasm32-unknown-unknown has an ABI incompatibility which means you cannot interoperate between C compiled to Wasm and Rust compiled to Wasm. wasm32-wasi works, but now you have to have a WASI implementation in the browser and that's still very immature. Tools like wasm-bindgen or wasm-pack don't work with wasm32-wasi either.
Basically you have the Web Platform backend (wasm32-unknown-unknown) that plays well with the browser part, but does not play well with the interoperability across languages part. And you have the WASI backend (wasm32-wasi) that plays well with the interoperability across languages part but does not play well with browser part.