This is just turning out to be the acid craze of our generation. We need a PSA. If you take a heroic dose of a powerful hallucinogen with little prior experience or preparation you stand a chance of breaking your brain. Doing ayahuasca with some unknown "shaman" in a jungle "wellness retreat" is not the same as going to a spa and getting acupuncture. It's more like going skydiving with an "instructor" that just hands you a parachute and says Jump!