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Comment by AcerbicZero | Hacker News Reader

I'm not surprised Adderall took the top spot; as far as "wonder drugs" go, it basically checks all the boxes. Energy, weight loss, motivation, the whole thing all in one nice little package. I think the trap is that over time it doesn't work exactly like it did before, and if you take it every single day you can get burned out. I like to skip a day or two over the weekend, to help start the week out a bit more fresh, but to each their own.

It's not comforting to know that my prefered answer to this (adult diagnosed) ADHD problem puts me right next to the meth addicts without teeth, but it's a risk that has paid off massively for me.

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In regards to the difference in effect between Adderall and illegal street meth, Scott thinks the biggest difference is the dosage size, effectively around 50x higher for street meth: https://astralcodexten.substack.com/p/drug-users-use-a-lot-o...

Dosis sola facit venenum.

And particularly the means--smoking it versus taking orally. A lot of these stims are terrible if snorted or injected, they used to warn patients never to do that or risk becoming addicted.

There is a methamphetamine that is prescribed to ADD's, not the same as the street version of course.

This may not actually be the case: https://www.theatlantic.com/magazine/archive/2021/11/the-new...

I've done a decent amount of drugs, and I've been around people who have done a hell of a lot more, but I recently had a friend develop a meth problem, and I have to say, there is something remarkably different about how issue compared to what I've seen in my life.

> I think the trap is that over time it doesn't work exactly like it did before, and if you take it every single day you can get burned out.

You may have a magnesium deficiency. Tolerance to Adderall definitely isn’t guaranteed.

NAC can also help in some people.

(both of these recommended by my psych not just /r/nootropics)

Adderall compared to smoking meth is like drinking green tea vs chewing up a handful of caffeine pills.

It has changed my life in a pretty beneficial way, but totally agree about having days off. I take 3 days off a week and refuse to let my doctor bump up the pill size.

> I think the trap is that over time it doesn't work exactly like it did before, and if you take it every single day you can get burned out.

After many years of 7d/wk use, it still works as expected for me. Diff bodies and all that.

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