Doing some quick searching around.
I know there is Crossover, Wine technically works on Mac from what I can tell also. So not sure if there is a technical reason Proton couldn't work on Mac other than just not building it.
Apple does talk a lot about gaming now on the iPhone and iPad, I would love to see them talk about it more on Mac (especially with how powerful these are) and maybe work with Proton like Steam is for the Steam Deck.