I’m triple vaccinated before anyone asks. I haven’t tested positive for Covid on rapid tests but a lot of people seem to be in the boat I’m in right now.
"Such a regime must only be followed under strict and qualified medical guidance to obviate any dangers, especially haemorrhagic bleeding, and of the therapy as a whole."
Also placebo are getting stronger https://drdavidhamilton.com/the-placebo-effect-is-getting-st... ;)
In the UK there is a large, ongoing clinical trial called 'RECOVER' to test different COVID treaments for hospitalised COVID patients. One of the trials included giving hospitalised patients aspirin. The trial was not looking at the treatment of long-covid symptoms (at least not directly in hospital patients).
"A total of 7351 patients were randomised to aspirin 150 mg once daily and compared with 7541 patients randomised to usual care alone. There was no evidence that aspirin treatment reduced mortality."
Link: RECOVERY trial finds aspirin does not improve survival for patients hospitalised with COVID-19: https://www.recoverytrial.net/news/recovery-trial-finds-aspi...
And, I'm aware of the research (and money) being poured into antivirals. Of course that's a thing. I'm sure there are billions if not trillions to be made off a pill you "simply take daily" to prevent the "severe and long covid." The headlines write themselves. But I seriously wonder what research is being done on "mild" covid cases using more cheap/traditional medicines. I know where I live, the doctors don't even talk to you unless your case gets severe - basically once you need oxygen supplementation. Prior to that, you're told to stay home and rest. I'm not even sure they create a record in their medical system.
This seems to be a problem with every account of "treatment X doesn't work". They wait until someone is half dead, use X, patient dies at same rate as without X, conclude X is worthless. "preventive" or "protective" are different words than "curative" and that seems to get overlooked in a lot of cases.
Doctor A: When I see someone with Covid Symptoms I give XYZ and they never end up in the hospital.
ER Doctor: We've tried X,Y, and Z in every combination with patients on ventilators and none of that saves them with any statistical significance.
They can both be correct.
Take for example the very recent approval of Molnupiravir:
https://www.bbc.co.uk/news/health-59163899
https://www.nejm.org/doi/full/10.1056/NEJMoa2116044
We conducted a phase 3, double-blind, randomized, placebo-controlled trial to evaluate the efficacy and safety of treatment with molnupiravir started within 5 days after the onset of signs or symptoms in nonhospitalized, unvaccinated adults with mild-to-moderate, laboratory-confirmed Covid-19 and at least one risk factor for severe Covid-19 illness.
Also, adverse-drug interactions is potentially a a major killer already in the US, sometimes from doctors making mistakes, and often from people using OTC drugs outside of their safe regime.
So then, we might wait until it is clear that intervention is necessary, but now the intervention also probably needs to be much more aggressive.
And besides, we do have a pretty good preventative/protective option already in vaccines. It is only when breakthrough cases lead to hospitalization that we then need to pull out the backup strategies, otherwise, we’ve seen that statistically our primed immune systems are usually pretty good at dealing with it on their own.
I’m not worried about mortality so much as getting over the strange long effects I’m feeling. I see this study as well.
https://www.webmd.com/lung/news/20210315/low-dose-aspirin-ma...
> But Magen's group found that people who'd already been taking low-dose aspirin to reduce their risk of heart disease had a 29% lower risk of contracting COVID-19 compared to those who didn't take aspirin, and that rates of aspirin use were much lower among COVID-19 patients than among those who didn't get infected.
>Among people who did get COVID-19, the time it took for SARS-CoV-2 PCR test results to go from positive to negative was significantly shorter among those who used aspirin, and the duration of their disease was two-three days shorter, depending upon preexisting health conditions.
How is survival defined? Do they mean "gets released from hospital vs. dies in hospital"? Because it seems a lot of things that can reduce severity of Covid (including vitamin D for example) don't change much at the last minute when you're at deaths door.
In this case, we're talking about long Covid symptoms so it would seem a reduction in 1-year mortality should be the deciding factor (since Severe Covid patients who "survive" still have significantly increase mortality over the next year).
Even the inactivated virus ones. They're just a very small viral load with an adjuvant to enhance immune response.
Do you actually have any evidence to back this up? Cells have a myriad of receptor sites, and single bindings without other resultant activity are highly unlikely to cause the cell significant damage.
The side effects of the vaccines have nothing to do with the vaccine particles themselves and everything to do with your body's immune response.
I think there's enough evidence out there that spike from vaccines circulate widely. I can dig it up if you want?
For a sample reference: https://journals.asm.org/doi/10.1128/JVI.00203-21
Just hang in there you’ll feel better soon.
https://www.nytimes.com/2021/10/12/health/aspirin-heart-atta...
Hmm, this is probably hardcore anecdata and off topic but a friend of mine who got Corona pretty bad (but not hospital bad) said that once he took Aspirin his symptoms weren't that bad anymore.
I couldn’t handle side effects, so I switched to Aspirin. It mostly works. But not as well. Side effects aren’t as bad. Doctors are pissed. But quality of life matters.
I would absolutely NOT do the same with ibuprofen or any other NSAID. All other NSAIDs but aspirin have been shown to reduce blood vessel elasticity after habitual use. Adopting any med for regular use is not something to take lightly.
"Ibuprofen, aspirin, and COX-2s all belong to the class of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). Most of them boost blood pressure and can counteract the effect of some blood-pressure drugs. They can also impair blood vessels' ability to relax and may stimulate the growth of smooth muscle cells inside arteries. All these changes can contribute to the artery-clogging process known as atherosclerosis."
https://www.health.harvard.edu/press_releases/nsaid-side-eff...
If aspirin did anything for covid you'd be seeing it on the news every single day for the past two years.
And yet there’s hardly any mention of them, let alone “everyday”.
https://www.covid19treatmentguidelines.nih.gov/tables/fluvox...
"No difference between arms in time to symptom resolution"
"Fluvoxamine did not impact time to symptom resolution"But I also found for remdesivir, which in the US and Israel is given like candy. My point being “hear about it everyday” is more related to politics and agenda than actual efficiency.