As I understand it asynchronous logic stopped being a common thing decades ago, so those sorts of glitches aren't possible (or less possible?) now. The hard stuff in simulation now is probably handling multiple clock domains.
This is all about reducing power consumption down in the nA range when the CPU is turned off but the RTC keeps ticking over.
Multiple clock domains definitely tricky though!
http://www.sunburst-design.com/papers/CummingsSNUG2008Boston...